Alterations in the glutathione-redox balance induced by the bio-insecticide Spinosad in CHO-K1 and Vero cells

Ecotoxicology and Environmental Safety

Volumn 70, Issue 2, 2008, Pages 251-258

  Pérez Pertejo, Yolanda ^a   Reguera, Rosa M ^a   Ordóñez, David ^a   Balaña Fouce, Rafael ^a  

^a UNIVERSITY OF LEÓN   (Spain)

Author keywords

Antioxidants; Basal cytotoxicity; Glutathione redox cycle; Spinosad; Spinosad induced cell damage; Spinosyns

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BOVINE SERUM ALBUMIN; GLUTATHIONE; INSECTICIDE; MALONALDEHYDE; SERUM ALBUMIN; SPINOSAD; UNCLASSIFIED DRUG;

ALDEHYDE; ANTIOXIDANT; BIOASSAY; BIOPESTICIDE; DOSE-RESPONSE RELATIONSHIP; ENZYME ACTIVITY; MAMMAL; OXIDATION; PEPTIDE; PROTEIN; SERUM; TOXICITY; VITAMIN;

ANIMAL CELL; ARTICLE; CELL DAMAGE; CELL VIABILITY; CHO CELL; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME INDUCTION; FETAL CALF SERUM; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; VERO CELL;

ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; CHO CELLS; CRICETINAE; CRICETULUS; DRUG COMBINATIONS; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; INSECTICIDES; LIPID PEROXIDATION; MACROLIDES; MALONDIALDEHYDE; OXIDATION-REDUCTION; VERO CELLS; VITAMIN E;

BOVINAE; MAMMALIA;

EID: 42049083746     PISSN: 01476513     EISSN: 10902414     Source Type: Journal    
DOI: 10.1016/j.ecoenv.2007.06.009     Document Type: Article

References (29)

1. Akerboom T.P.M., and Sies H. Assay of glutathione, glutathione disulfide and glutathione mixed disulfides in biological samples. Methods Enzymol. 77 (1981) 373-382
2. Anderson M.E. Determination of glutathione and glutathione disulfide in biological samples. Methods Enzymol. 113 (1985) 548-555
3. Bayoumi A.E., Perez-Pertejo Y., Ordonez C., Reguera R.M., Cubria J.C., Balana-Fouce R., and Ordonez D. Alterations on polyamine content and glutathione metabolism induced by different concentrations of paraquat in CHO-K1 cells. Toxicol In Vitro 14 (2000) 211-217
4. Bond J.G., Marina C.F., and Williams T. The naturally derived insecticide Spinosad is highly toxic to Aedes and Anopheles mosquito larvae. Med. Vet. Entomol. 18 (2004) 50-56
5. Borenfreund E., and Puerner J.A. Toxicity determined in vitro by morphological alteration and neutral red absorption. Toxicol. Lett. 24 (1985) 119-124
6. Bradford M. A rapid sensitive method for quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
7. Carlberg I., and Mannervik B. Glutathione reductase. Methods Enzymol. 113 (1985) 484-490
8. Carr A., and Frei B. Does vitamin C act as a pro-oxidant under physiological conditions?. FASEB J. 13 (1999) 1007-1024
9. Cook R.J. Advances in plant health, management in the twentieth century. Annu. Rev. Phytopathol. 38 (2000) 95-116
10. Cutler R.G. Antioxidants and longevity of mammalian species. Basic Life Sci. 35 (1985) 15-73
11. Dent D. Insect Pest Management (2000), CABI Publishing, Wallingford, UK 410pp
12. 14C labelled XDE-105 (factor A) in Fischer 344 rats. Unpublished Report No. DECO-HET-DR-0323-1194-012, submitted for publication to WHO by Dow AgroSciences, Letcombe, United Kingdom.
13. Evans P., and Halliwell B. Micronutrients: oxidant/antioxidant status. Br. J. Nutr. 85 (2001) S67-S74
14. Garcia-Fernandez A.J., Bayoumi A.E., Perez-Pertejo Y., Motas M., Reguera R.M., Ordonez C., Balana-Fouce R., and Ordonez D. Alterations of the glutathione-redox balance induced by metals in CHO-K1 cells. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 132 (2002) 365-373
15. Grothe, D.W., Boss, S.M., Gries, C.L., 1992. A subchronic toxicity study in CD-1 mice administered XDE-105 in the diet for 3 months. Unpublished Report No. M01290, Toxicology Research Laboratories, Lilly Research Laboratories, USA, submitted for publication to WHO by Dow AgroSciences, Letcombe, United Kingdom.
16. Habig W.H., Pabst M.J., and Jakoby W.B. Glutathione S-transferase. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 249 (1974) 7130-7139
17. Hanley Jr. T.R., Breslin W.J., Quast J.F., and Carney E.W. Evaluation of Spinosad in a two-generation dietary reproduction study using Sprague-Dawley rats. Toxicol. Sci. 67 (2002) 144-152
18. Kirst H.A., Michel K.H., Mynderse J.S., Chao E.H., Yao R.C., Nakatsukasa W.M., Doeck L.D., Occlowitz J., Paschel J.W., Deeter J.B., and Thompson G.D. Discovery, isolation and structure elucidation of a family of structurally unique fermentation-derived tetracyclic macrolides. In: Fenyes J.G., and Steffens J.J. (Eds). Synthesis and Chemistry of Agrochemicals III (1992), American Chemical Society, Washington, DC 214-225
19. Lee T.C., and Ho I.C. Differential cytotoxic effects of arsenic on human and animal cells. Environ. Health Perspect. 102 (1994) 101-105
20. Ramasubramanian T., and Regupathy A. Laboratory and field evaluation of spinosad against pyrethroid resistant population of Helicoverpa armigera hub. J. Biol. Sci. 4 (2004) 142-145
21. Salgado V.L. Studies on the mode of action of Spinosad: insect symptoms and physiological correlates. Pestic. Biochem. Physiol. 60 (1998) 91-102
22. Salgado V.L., Sheets J.J., Watson G.B., and Schmidt A.L. Studies on the mode of action of Spinosad: the internal effective concentration and the concentration dependence of neural excitation. Pestic. Biochem. Physiol. 60 (1998) 103-110
23. Schoonover J.R., and Larson L.L. Laboratory activity of Spinosad on non-target beneficial arthropods, 1994. Arthropod Manage. Tests 20 (1995) 357-358
24. Smith L.L., Rose M.S., and Wyatt I. The pathology and biochemistry of paraquat. Oxygen Free-Radicals and Tissue Damage. CIBA Foundation Series vol. 65 (1979), CIBA Foundation, London 321-341
25. Stebbins K.E., Bond D.M., Novilla M.N., and Reasor M.J. Spinosad insecticide: subchronic and chronic toxicity and lack of carcinogenicity in CD-1 mice. Toxicol. Sci. 65 (2002) 276-287
26. Warner B., Papes R., Heile M., Spitz D., and Wispe J. Expression of human Mn SOD in Chinese hamster ovary cells confers protection from oxidant injury. Am. J. Physiol. 264 (1993) L598-L605
27. Wendel A. Glutathione peroxidase. Methods Enzymol. 77 (1981) 325-333
28. Wills E.D. Evaluation of lipid peroxidation in lipids and biological membranes. In: Snell K., and Mullok B. (Eds). Biochemical Toxicology: a Practical Approach (1987), IRL Press, Oxford 407-420
29. Yano B.L., Bond D.M., Novilla M.N., McFadden L.G., and Reasor M.J. Spinosad insecticide: subchronic and chronic toxicity and lack of carcinogenicity in Fischer 344 rats. Toxicol. Sci. 65 (2002) 288-298