메뉴 건너뛰기




Volumn 3, Issue 3, 2008, Pages 375-379

T cell responses generated by HIV vaccines in clinical trials

Author keywords

ELISpot; HIV vaccine; Intracellular cytokine staining; T cell immunogenicity

Indexed keywords

ADENOVIRUS VECTOR; CANARYPOX VACCINE; DNA VACCINE; GAG PROTEIN; GAMMA INTERFERON; GLYCOPROTEIN GP 120; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; NEF PROTEIN; NEFTAT PROTEIN; NEUTRALIZING ANTIBODY; PEPTIDE; PLACEBO; POL PROTEIN; REAGENT; RECOMBINANT DNA; RECOMBINANT PROTEIN; RECOMBINANT VACCINE; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG; VACCINIA VACCINE; VIRUS ENVELOPE PROTEIN; VIRUS FUSION PROTEIN; VIRUS VACCINE;

EID: 42049083555     PISSN: 1746630X     EISSN: 17466318     Source Type: Journal    
DOI: 10.1097/COH.0b013e3282fbaaa7     Document Type: Review
Times cited : (10)

References (22)
  • 1
    • 34147176167 scopus 로고    scopus 로고
    • Defining blood processing parameters for optimal detection of cryopreserved antigen-specific responses for HIV vaccine trials
    • Bull M, Lee D, Stucky J, et al. Defining blood processing parameters for optimal detection of cryopreserved antigen-specific responses for HIV vaccine trials. J Immunol Methods 2007; 322:57-69.
    • (2007) J Immunol Methods , vol.322 , pp. 57-69
    • Bull, M.1    Lee, D.2    Stucky, J.3
  • 2
    • 33846813761 scopus 로고    scopus 로고
    • Enhanced rates and magnitude of immune responses detected against an HIV vaccine: Effect of using an optimized process for isolating PBMC
    • Kierstead LS, Dubey S, Meyer B, et al. Enhanced rates and magnitude of immune responses detected against an HIV vaccine: effect of using an optimized process for isolating PBMC. AIDS Res Hum Retroviruses 2007; 23:86-92.
    • (2007) AIDS Res Hum Retroviruses , vol.23 , pp. 86-92
    • Kierstead, L.S.1    Dubey, S.2    Meyer, B.3
  • 3
    • 34247635041 scopus 로고    scopus 로고
    • Detection of HIV vaccine-induced cell-mediated immunity in HIV-seronegative clinical trial participants using an optimized and validated enzyme-linked immunospot assay
    • Dubey S, Clair J, Fu TM, et al. Detection of HIV vaccine-induced cell-mediated immunity in HIV-seronegative clinical trial participants using an optimized and validated enzyme-linked immunospot assay. J Acquir Immune Defic Syndr 2007; 45:20-27.
    • (2007) J Acquir Immune Defic Syndr , vol.45 , pp. 20-27
    • Dubey, S.1    Clair, J.2    Fu, T.M.3
  • 4
    • 34248149301 scopus 로고    scopus 로고
    • Optimization and validation of an 8-color intracellular cytokine staining (ICS) assay to quantify antigen-specific T cells induced by vaccination
    • Horton H, Thomas EP, Stucky JA, et al. Optimization and validation of an 8-color intracellular cytokine staining (ICS) assay to quantify antigen-specific T cells induced by vaccination. J Immunol Methods 2007; 323:39-54.
    • (2007) J Immunol Methods , vol.323 , pp. 39-54
    • Horton, H.1    Thomas, E.P.2    Stucky, J.A.3
  • 5
    • 34248331317 scopus 로고    scopus 로고
    • Enhanced detection of human immunodeficiency virus type 1 (HIV-1) Nef-specific T cells recognizing multiple variants in early HIV-1 infection
    • Malhotra U, Li F, Nolin J, et al. Enhanced detection of human immunodeficiency virus type 1 (HIV-1) Nef-specific T cells recognizing multiple variants in early HIV-1 infection. J Virol 2007; 81:5225-5237.
    • (2007) J Virol , vol.81 , pp. 5225-5237
    • Malhotra, U.1    Li, F.2    Nolin, J.3
  • 6
    • 38449086859 scopus 로고    scopus 로고
    • Increased sequence diversity coverage improves detection of HIV-specific T cell responses
    • Frahm N, Kaufmann DE, Yusim K, et al. Increased sequence diversity coverage improves detection of HIV-specific T cell responses. J Immunol 2007; 179:6638-6650.
    • (2007) J Immunol , vol.179 , pp. 6638-6650
    • Frahm, N.1    Kaufmann, D.E.2    Yusim, K.3
  • 7
    • 34250303350 scopus 로고    scopus 로고
    • Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major
    • Darrah PA, Patel DT, De Luca PM, et al. Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major. Nat Med 2007; 13:843-850.
    • (2007) Nat Med , vol.13 , pp. 843-850
    • Darrah, P.A.1    Patel, D.T.2    De Luca, P.M.3
  • 8
    • 34250327922 scopus 로고    scopus 로고
    • Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses
    • Precopio ML, Betts MR, Parrino J, et al. Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses. J Exp Med 2007; 204:1405-1416.
    • (2007) J Exp Med , vol.204 , pp. 1405-1416
    • Precopio, M.L.1    Betts, M.R.2    Parrino, J.3
  • 9
    • 33847121696 scopus 로고    scopus 로고
    • Phase 2 study of an HIV-1 canarypox vaccine (vCP1452) alone and in combination with rgp120: Negative results fail to trigger a phase 3 correlates trial
    • Russell ND, Graham BS, Keefer MC, et al. Phase 2 study of an HIV-1 canarypox vaccine (vCP1452) alone and in combination with rgp120: negative results fail to trigger a phase 3 correlates trial. J Acquir Immune Defic Syndr 2007; 44:203-212.
    • (2007) J Acquir Immune Defic Syndr , vol.44 , pp. 203-212
    • Russell, N.D.1    Graham, B.S.2    Keefer, M.C.3
  • 10
    • 34748888347 scopus 로고    scopus 로고
    • Lessons from a multisite international trial in the Caribbean and South America of an HIV-1 Canarypox vaccine (ALVAC-HIV vCP1452) with or without boosting with MN rgp120
    • Cleghorn F, Pape JW, Schechter M, et al. Lessons from a multisite international trial in the Caribbean and South America of an HIV-1 Canarypox vaccine (ALVAC-HIV vCP1452) with or without boosting with MN rgp120. J Acquir Immune Defic Syndr 2007; 46:222-230.
    • (2007) J Acquir Immune Defic Syndr , vol.46 , pp. 222-230
    • Cleghorn, F.1    Pape, J.W.2    Schechter, M.3
  • 11
    • 34848908400 scopus 로고    scopus 로고
    • A phase 1/2 comparative vaccine trial of the safety and immunogenicity of a CRF01_AE (subtype E) candidate vaccine: ALVAC-HIV (vCP1521) prime with oligomeric gp160 (92TH023/LAI-DID) or bivalent gp120 (CM235/SF2) boost
    • Thongcharoen P, Suriyanon V, Paris RM, et al. A phase 1/2 comparative vaccine trial of the safety and immunogenicity of a CRF01_AE (subtype E) candidate vaccine: ALVAC-HIV (vCP1521) prime with oligomeric gp160 (92TH023/LAI-DID) or bivalent gp120 (CM235/SF2) boost. J Acquir Immune Defic Syndr 2007; 46:48-55.
    • (2007) J Acquir Immune Defic Syndr , vol.46 , pp. 48-55
    • Thongcharoen, P.1    Suriyanon, V.2    Paris, R.M.3
  • 12
    • 33845207796 scopus 로고    scopus 로고
    • Durable HIV-1 antibody and T-cell responses elicited by an adjuvanted multiprotein recombinant vaccine in uninfected human volunteers
    • Goepfert PA, Tomaras GD, Horton H, et al. Durable HIV-1 antibody and T-cell responses elicited by an adjuvanted multiprotein recombinant vaccine in uninfected human volunteers. Vaccine 2007; 25:510-518.
    • (2007) Vaccine , vol.25 , pp. 510-518
    • Goepfert, P.A.1    Tomaras, G.D.2    Horton, H.3
  • 13
    • 33845439080 scopus 로고    scopus 로고
    • Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 candidate vaccine delivered by a replication-defective recombinant adenovirus vector
    • Catanzaro AT, Koup RA, Roederer M, et al. Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 candidate vaccine delivered by a replication-defective recombinant adenovirus vector. J Infect Dis 2006; 194:1638-1649.
    • (2006) J Infect Dis , vol.194 , pp. 1638-1649
    • Catanzaro, A.T.1    Koup, R.A.2    Roederer, M.3
  • 14
    • 34247201441 scopus 로고    scopus 로고
    • Phase I clinical evaluation of a six-plasmid multiclade HIV-1 DNA candidate vaccine
    • Catanzaro AT, Roederer M, Koup RA, et al. Phase I clinical evaluation of a six-plasmid multiclade HIV-1 DNA candidate vaccine. Vaccine 2007; 25:4085-4092.
    • (2007) Vaccine , vol.25 , pp. 4085-4092
    • Catanzaro, A.T.1    Roederer, M.2    Koup, R.A.3
  • 15
    • 33845412550 scopus 로고    scopus 로고
    • Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 DNA candidate vaccine
    • Graham BS, Koup RA, Roederer M, et al. Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 DNA candidate vaccine. J Infect Dis 2006; 194:1650-1660.
    • (2006) J Infect Dis , vol.194 , pp. 1650-1660
    • Graham, B.S.1    Koup, R.A.2    Roederer, M.3
  • 16
    • 35148818748 scopus 로고    scopus 로고
    • AIDS research, Promising AIDS vaccine's failure leaves field reeling
    • Cohen J. AIDS research, Promising AIDS vaccine's failure leaves field reeling. Science 2007; 318:28-29.
    • (2007) Science , vol.318 , pp. 28-29
    • Cohen, J.1
  • 17
    • 36249005448 scopus 로고    scopus 로고
    • AIDS research, Did Merck's failed HIV vaccine cause harm?
    • Cohen J. AIDS research, Did Merck's failed HIV vaccine cause harm? Science 2007; 318:1048-1049.
    • (2007) Science , vol.318 , pp. 1048-1049
    • Cohen, J.1
  • 18
    • 37549071908 scopus 로고    scopus 로고
    • AIDS research, Trials of NIH's AIDS vaccine get a yellow light
    • Cohen J, Lester B. AIDS research, Trials of NIH's AIDS vaccine get a yellow light. Science 2007; 318:1852.
    • (2007) Science , vol.318 , pp. 1852
    • Cohen, J.1    Lester, B.2
  • 19
    • 38749096240 scopus 로고    scopus 로고
    • The failed HIV Merck vaccine study: A step back or a launching point for future vaccine development?
    • Sekaly RP. The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development? J Exp Med 2008; 205:7-12.
    • (2008) J Exp Med , vol.205 , pp. 7-12
    • Sekaly, R.P.1
  • 20
    • 29244455769 scopus 로고    scopus 로고
    • Attenuation of simian immunodeficiency virus SIVmac239 infection by prophylactic immunization with dna and recombinant adenoviral vaccine vectors expressing Gag
    • Casimiro DR, Wang F, Schleif WA, et al. Attenuation of simian immunodeficiency virus SIVmac239 infection by prophylactic immunization with dna and recombinant adenoviral vaccine vectors expressing Gag. J Virol 2005; 79:15547-15555.
    • (2005) J Virol , vol.79 , pp. 15547-15555
    • Casimiro, D.R.1    Wang, F.2    Schleif, W.A.3
  • 21
    • 4644225721 scopus 로고    scopus 로고
    • Heterologous human immunodeficiency virus type 1 priming-boosting immunization strategies involving replication-defective adenovirus and poxvirus vaccine vectors
    • Casimiro DR, Bett AJ, Fu TM, et al. Heterologous human immunodeficiency virus type 1 priming-boosting immunization strategies involving replication-defective adenovirus and poxvirus vaccine vectors. J Virol 2004; 78:11434-11438.
    • (2004) J Virol , vol.78 , pp. 11434-11438
    • Casimiro, D.R.1    Bett, A.J.2    Fu, T.M.3
  • 22
    • 0038664390 scopus 로고    scopus 로고
    • Comparative immunogenicity in rhesus monkeys of DNA plasmid, recombinant vaccinia virus, and replication-defective adenovirus vectors expressing a human immunodeficiency virus type 1 gag gene
    • Casimiro DR, Chen L, Fu TM, et al. Comparative immunogenicity in rhesus monkeys of DNA plasmid, recombinant vaccinia virus, and replication-defective adenovirus vectors expressing a human immunodeficiency virus type 1 gag gene. J Virol 2003; 77:6305-6313.
    • (2003) J Virol , vol.77 , pp. 6305-6313
    • Casimiro, D.R.1    Chen, L.2    Fu, T.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.