Geographic patterns of genome admixture in latin American mestizos

PLoS Genetics

Volumn 4, Issue 3, 2008, Pages

  Wang, Sijia ^a   Ray, Nicolas ^b   Rojas, Winston ^c   Parra, Maria V ^c   Bedoya, Gabriel ^c   Gallo, Carla ^d   Poletti, Giovanni ^d   Mazzotti, Guido ^d   Hill, Kim ^e   Hurtado, Ana M ^e   Camrena, Beatriz ^f   Nicolini, Humberto ^f   Klitz, William ^g,h   Barrantes, Ramiro ⁱ   Molina, Julio A ^j   Freimer, Nelson B ^j   Bortolini, Maria Cátira ^k   Salzano, Francisco M ^k   Petzl Erler, Maria L ^l   Tsuneto, Luiza T ^l   Dipierri, José E ^m   Alfaro, Emma L ^m   Bailliet, Graciela ⁿ   Bianchi, Nestor O ⁿ   Llop, Elena ^o   Rothhammer, Francisco ^o,p   Excoffier, Laurent ^b   Ruiz Linares, Andrés ^a   more..

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF BERN   (Switzerland)

^c UNIVERSIDAD DE ANTIOQUIA   (Colombia)

^d UNIVERSIDAD PERUANA CAYETANO HEREDIA   (Peru)

^e UNIVERSITY OF NEW MEXICO   (United States)

^f UNIVERSIDAD AUTÓNOMA DE LA CIUDAD DE MÉXICO   (Mexico)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h PUBLIC HEALTH INSTITUTE   (United States)

ⁱ UNIVERSIDAD DE COSTA RICA   (Costa Rica)

^j UNIVERSITY OF CALIFORNIA   (United States)

^k FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^l FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^m UNIVERSIDAD NACIONAL DE JUJUY   (Argentina)

ⁿ Instituto Multidisciplinario de Biologia Celular   (Argentina)

^o UNIVERSITY OF CHILE   (Chile)

^p UNIVERSIDAD DE TARAPACÁ   (Chile)

more..

Author keywords

[No Author keywords available]

Indexed keywords

MICROSATELLITE DNA;

AFRICAN AMERICAN; AMERICAN INDIAN; ARTICLE; AUTOSOMAL INHERITANCE; EUROPE; FEMALE; GENETIC ANALYSIS; GENETIC VARIABILITY; GENOME; GEOGRAPHIC AND GEOLOGICAL PHENOMENA; HUMAN; MALE; PLESIOMORPHY; RACE DIFFERENCE; SOUTH AND CENTRAL AMERICA; X CHROMOSOME; CAUCASIAN; GENETICS; HETEROZYGOTE; NEGRO; POPULATION GENETICS;

AFRICAN CONTINENTAL ANCESTRY GROUP; AMERICAN NATIVE CONTINENTAL ANCESTRY GROUP; CHROMOSOMES, HUMAN, X; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETICS, POPULATION; GENOME, HUMAN; HETEROZYGOTE; HUMANS; LATIN AMERICA; MALE; MICROSATELLITE REPEATS; VARIATION (GENETICS);

EID: 41949133594     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000037     Document Type: Article

References (47)

1. Zhu X, Cooper RS, Elston RC (2004) Linkage analysis of a complex disease through use of admixed populations. Am J Hum Genet 74: 1136-1153.
2. Smith MW, O'Brien SJ (2005) Mapping by admixture linkage disequilibrium: advances, limitations and guidelines. Nat Rev Genet 6: 623-632.
3. McKeigue PM (2005) Prospects for admixture mapping of complex traits. Am J Hum Genet 76: 1-7.
4. Tang H, Coram M, Wang P, Zhu X, Risch N (2006) Reconstructing genetic ancestry blocks in admixed individuals. Am J Hum Genet 79: 1-12.
5. Seldin MF (2007) Admixture mapping as a tool in gene discovery. Curr Opin Genet Dev 17: 177-181.
6. Zhu X, Luke A, Cooper RS, Quertermous T, Hanis C, et al. (2005) Admixture mapping for hypertension loci with genome-scan markers. Nat Genet 37: 177-181.
7. Smith MW, Patterson N, Lautenberger JA, Truelove AL, McDonald GJ, et al. (2004) A high-density admixture map for disease gene discovery in african americans. Am J Hum Genet 74: 1001-1013.
8. Tian C, Hinds DA, Shigeta R, Kittles R, Ballinger DG, et al. (2006) A genomewide single-nucleotide-polymorphism panel with high ancestry information for African American admixture mapping. Am J Hum Genet 79: 640-649.
9. Reich D, Patterson N, De Jager PL, McDonald GJ, Waliszewska A, et al. (2005) A whole-genome admixture scan finds a candidate locus for multiple sclerosis susceptibility. Nat Genet 37: 1113-1118.
10. Deo RC, Patterson N, Tandon A, McDonald GJ, Haiman CA, et al. (2007) A High-Density Admixture Scan in 1,670 African Americans with Hypertension. PLoS Genet 3: e196.
11. Reich D, Patterson N, Ramesh V, De Jager PL, McDonald GJ, et al. (2007) Admixture mapping of an allele affecting interleukin 6 soluble receptor and interleukin 6 levels. Am J Hum Genet 80: 716-726.
12. Gonzalez BE, Borrell LN, Choudhry S, Naqvi M, Tsai HJ, et al. (2005) Latino populations: a unique opportunity for the study of race, genetics, and social environment in epidemiological research. Am J Public Health 95: 2161-2168.
13. Mao X, Bigham AW, Mei R, Gutierrez G, Weiss KM, et al. (2007) A genomewide admixture mapping panel for hispanic/latino populations. Am J Hum Genet 80: 1171-1178.
14. Price AL, Patterson N, Yu F, Cox DR, Waliszewska A, et al. (2007) A genomewide admixture map for latino populations. Am J Hum Genet 80: 1024-1036.
15. Tian C, Hinds DA, Shigeta R, Adler SG, Lee A, et al. (2007) A genomewide single-nucleotide-polymorphism panel for Mexican American admixture mapping. Am J Hum Genet 80: 1014-1023.
16. Morner M (1967) Race Mixture in the History of Latin America. Little Brown & Company.
17. Sanchez-Albornoz N (1974) The population of Latin America: a history. Berkeley: University of California Press.
18. Burkholder MA, Johnson LL (2003) Colonial Latin America. Oxford University Press.
19. Collier S, Skidmore TE, Blakemore H (1992) Cambridge Encyclopedia of Latin America and the Caribbean. Cambridge: Cambridge University Press.
20. Sans M (2000) Admixture studies in Latin America: from the 20th to the 21st century. Hum Biol 72: 155-177.
21. Salzano FM, Bortolini MC (2002) The Evolution and Genetics of Latin American Populations. Cambridge University Press.
22. Cann HM, de Toma C, Cazes L, Legrand MF, Morel V, et al. (2002) A human genome diversity cell line panel. Science 296: 261-262.
23. Wang S, Lewis CM, Jakobsson M, Ramachandran S, Ray N, et al. (2007) Genetic Variation and Population Structure in Native Americans. PLoS Genet 3: e185.
24. Hoggart CJ, Shriver MD, Kittles RA, Clayton DG, McKeigue PM (2004) Design and analysis of admixture mapping studies. Am J Hum Genet 74: 965-978.
25. Falush D, Stephens M, Pritchard JK (2003) Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. Genetics 164: 1567-1587.
26. Freeman AR, Hoggart CJ, Hanotte O, Bradley DG (2006) Assessing the relative ages of admixture in the bovine hybrid zones of Africa and the Near East using X chromosome haplotype mosaicism. Genetics 173: 1503-1510.
27. Escamilla MA, Spesny M, Reus VI, Gallegos A, Meza L, et al. (1996) Use of linkage disequilibrium approaches to map genes for bipolar disorder in the Costa Rican population. Am J Med Genet 67: 244-253.
28. Service S, Deyoung J, Karayiorgou M, Roos JL, Pretorious H, et al. (2006) Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies. Nat Genet 38: 556-560.
29. Alfaro EL, Dipierri JE, Gutierrez NI, Vullo CM (2005) Genetic structure and admixture in urban populations of the Argentine North-West. Ann Hum Biol 32: 724-737.
30. Marrero AR, Bravi C, Stuart S, Long JC, Pereira das Neves LF, et al. (2007) Pre- and post-Columbian gene and cultural continuity: the case of the Gaucho from southern Brazil. Hum Hered 64: 160-171.
31. Bonilla C, Parra EJ, Pfaff CL, Dios S, Marshall JA, et al. (2004) Admixture in the Hispanics of the San Luis Valley, Colorado, and its implications for complex trait gene mapping. Ann Hum Genet 68: 139-153.
32. Seldin MF, Tian C, Shigeta R, Scherbarth HR, Silva G, et al. (2007) Argentine population genetic structure: large variance in Amerindian contribution. Am J Phys Anthropol 132: 455-462.
33. Carvajal-Carmona LG, Soto ID, Pineda N, Ortiz-Barrientos D, Duque C, et al. (2000) Strong Amerind/White Sex Bias and a Possible Sephardic Contribution among the Founders of a Population in Northwest Colombia. Am J Hum Genet 67: 1287-1295.
34. Green LD, Derr JN, Knight A (2000) mtDNA affinities of the peoples of North-Central Mexico. Am J Hum Genet 66: 989-998.
35. Carvajal-Carmona LG, Ophoff R, Service S, Hartiala J, Molina J, et al. (2003) Genetic demography of Antioquia (Colombia) and the Central Valley of Costa Rica. Hum Genet 112: 534-541.
36. Bedoya G, Montoya P, Garcia J, Soto I, Bourgeois S, et al. (2006) Admixture dynamics in Hispanics: a shift in the nuclear genetic ancestry of a South American population isolate. Proc Natl Acad Sci U S A 103: 7234-7239.
37. Dipierri JE, Alfaro E, Martinez-Marignac VL, Bailliet G, Bravi CM, et al. (1998) Paternal directional mating in two Amerindian subpopulations located at different altitudes in northwestern Argentina. Hum Biol 70: 1001-1010.
38. Sans M, Weimer TA, Franco MH, Salzano FM, Bentancor N, et al. (2002) Unequal contributions of male and female gene pools from parental populations in the African descendants of the city of Melo, Uruguay. Am J Phys Anthropol 118: 33-44.
39. Parra EJ, Marcini A, Akey J, Martinson J, Batzer MA, et al. (1998) Estimating African American admixture proportions by use of population- specific alleles. Am J Hum Genet 63: 1839-1851.
40. Ruhlen M (1991) A Guide to the World's Languages. Stanford, Calif.: Stanford University Press.
41. Villa M, Rodriguez J (1996) Demographic trends in Latin America's metropolises, 1950-1990. In: Gilbert A, ed. The Mega-city in Latin America. Tokyo: United Nations University Press. pp 25-52.
42. Patterson N, Hattangadi N, Lane B, Lohmueller KE, Hafler DA, et al. (2004) Methods for high-density admixture mapping of disease genes. Am J Hum Genet 74: 979-1000.
43. Henriquez H, Moraga M, Llop E, Rothhammer F (2004) [Molecular and genetic characterization of Changos descendants living in Paposo Cove]. Rev Med Chil 132: 663-672.
44. Campos-Sanchez R, Barrantes R, Silva S, Escamilla M, Ontiveros A, et al. (2006) Genetic structure analysis of three Hispanic populations from Costa Rica, Mexico, and the southwestern United States using Y-chromosome STR markers and mtDNA sequences. Hum Biol 78: 551-563.
45. Pritchard JK, Stephens M, Donnelly P (2000) Inference of population structure using multilocus genotype data. Genetics 155: 945-959.
46. Weir BS (1996) Genetic Data Analysis II. Sunderland, MA: Sinauer.
47. Ray N (2005) PATHMATRIX: a geographical information system tool to compute effective distances among samples. Molecular Ecology Notes 5: 177-180.