Cytochrome b5 inhibits electron transfer from NADPH-cytochrome P450 reductase to ferric cytochrome P450 2B4

Journal of Biological Chemistry

Volumn 283, Issue 9, 2008, Pages 5217-5225

  Zhang, Haoming ^a   Hamdane, Djemel ^a   Im, Sang Choul ^a   Waskell, Lucy ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BINDING SITES; ELECTRON TRANSITIONS; ENZYME ACTIVITY; EXPERIMENTS; MANGANESE COMPOUNDS;

CYTOCHROME B; CYTOCHROME P450; ELECTRON TRANSFERS; EXPERIMENTAL CONDITIONS; HIGHER CONCENTRATIONS; MOLAR RATIOS; MUTAGENESIS STUDIES; OXIDATION STATE CHANGES; PRE-REQUISITES; RATE OF REDUCTIONS;

MANGANESE;

CYTOCHROME B5; CYTOCHROME P450; FERRIC CYTOCHROME P450 2B4; MANGANESE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE; UNCLASSIFIED DRUG; CYTOCHROME P 450 CYP2B4 (RABBIT); CYTOCHROME P-450 CYP2B4 (RABBIT); RECOMBINANT PROTEIN; UNSPECIFIC MONOOXYGENASE;

ARTICLE; BINDING SITE; CONCENTRATION RESPONSE; ELECTRON TRANSPORT; ENZYME INHIBITION; ESCHERICHIA COLI; NONHUMAN; OXIDATION KINETICS; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STEADY STATE; ANIMAL; CATALYSIS; CHEMISTRY; GENETICS; METABOLISM; PHYSIOLOGY; PROTEIN BINDING;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BINDING SITES; CATALYSIS; CYTOCHROMES B5; ELECTRON TRANSPORT; MANGANESE; MUTAGENESIS, SITE-DIRECTED; NADPH-FERRIHEMOPROTEIN REDUCTASE; PROTEIN BINDING; RECOMBINANT PROTEINS;

EID: 41949131364     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M709094200     Document Type: Article

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