Crystal Structure of the Peptidoglycan Recognition Protein at 1.8 Å Resolution Reveals Dual Strategy to Combat Infection Through Two Independent Functional Homodimers

Journal of Molecular Biology

Volumn 378, Issue 4, 2008, Pages 923-932

  Sharma, Pradeep ^a   Singh, Nagendra ^a   Sinha, Mau ^a   Sharma, Sujata ^a   Perbandt, M ^b   Betzel, C ^b   Kaur, Punit ^a   Srinivasan, A ^a   Singh, Tej P ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^b UNIVERSITY OF HAMBURG   (Germany)

Author keywords

antimicrobial activity; crystal structure; innate immunity; pattern recognition protein; peptidoglycan recognition protein

Indexed keywords

HOMODIMER; PEPTIDOGLYCAN RECOGNITION PROTEIN; PEPTIDOGLYCAN RECOGNITION PROTEIN S; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMICROBIAL ACTIVITY; ARTICLE; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; GRAM NEGATIVE BACTERIUM; HYDROPHOBICITY; INNATE IMMUNITY; MASTITIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; X RAY CRYSTALLOGRAPHY;

CAMELIDAE; MAMMALIA;

EID: 41949128157     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2008.03.018     Document Type: Article

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