Inhibition of MPEP on the development of morphine antinociceptive tolerance and the biosynthesis of neuronal nitric oxide synthase in rat spinal cord

Neuroscience Letters

Volumn 436, Issue 2, 2008, Pages 214-218

  Xu, Tao ^a   Jiang, Wei ^a   Du, Dongping ^a   Xu, Yongming ^a   Zhou, Quanhong ^a   Pan, Xiaorong ^b   Lou, Yejiang ^b   Xu, Liang ^c   Ma, Ke ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Intrathecal injection; Metabotropic glutamate receptor 5 (mGluR5); Morphine; Nitric oxide synthase (NOS); Tolerance

Indexed keywords

2 CHLORO 5 HYDROXYPHENYLGLYCINE; 2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; CALCIUM; METABOTROPIC RECEPTOR 5; MORPHINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEURONAL NITRIC OXIDE SYNTHASE; PROTEIN KINASE C;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; DRUG INHIBITION; DRUG POTENTIATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; GENE EXPRESSION REGULATION; GLYCINE; MALE; MORPHINE; NARCOTICS; NITRIC OXIDE SYNTHASE TYPE I; PAIN MEASUREMENT; PAIN THRESHOLD; PHENYLACETATES; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD; TIME FACTORS;

EID: 41949124475     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2008.03.028     Document Type: Article

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