Methodologies for Identifying the Neural Correlates of Consciousness

The Blackwell Companion to Consciousness

Volumn , Issue , 2007, Pages 551-566

  Rees, Geraint ^a   Frith, Chris D ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Ambiguous stimuli; Behavioral correlates; Conscious processing; Elicits activity; Visual stimuli

Indexed keywords

EID: 41949117613     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470751466.ch44     Document Type: Chapter

References (86)

1. Koch, C. (2004) The Quest for Consciousness: A Neurobiological Approach. Englewood, CO: Roberts.
2. Beck, D. M., Muggleton, N., Walsh, V., and Lavie, N. (2006) Right parietal cortex plays a critical role in change blindnes Cerebral Cortex May 16: 5, 712-17.
3. Beck, D. M., Rees, G., Frith, C. D., and Lavie, N. (2001) Neural correlates of change detection and change blindnes Nature Neuroscience 4: 6, 645-50.
4. Blake, R. and Logothetis, N. K. (2002) Visual competitio Nature Review: Neuroscience 3: 1, 13-21.
5. Blakemore, S. J., Oakley, D. A., and Frith, C. D. (2003) Delusions of alien control in the normal brai Neuropsychologia 41: 8, 1058-67.
6. Blakemore, S. J., Rees, G., and Frith, C. D. (1998) How do we predict the consequences of our actions? A functional imaging stud Neuropsychologia 36: 6, 521-29.
7. Cowey, A. and Walsh, V. (2000) Magnetically induced phosphenes in sighted, blind and blindsighted observer NeuroReport 11: 14, 3269-73.
8. Danckert, J., Ferber, S., Doherty, T., Steinmetz, H., Nicolle, D., and Goodale, M. A. (2002) Selective, nonlateralized impairment of motor imagery following right parietal damag Neurocase 8: 3, 194-204.
9. Dehaene, S., Naccache, L., Cohen, L., Bihan, D. L., Mangin, J. F., Poline, J. B. et al. (2001) Cerebral mechanisms of word masking and unconscious repetition primin Nature Neuroscience 4: 7, 752-8.
10. Dierks, T., Linden, D. E., Jandl, M., Formisano, E., Goebel, R., Lanfermann, H. et al. (1999) Activation of Heschl's gyrus during auditory hallucination Neuron 22: 3, 615-21.
11. Driver, J., Vuilleumier, P., Eimer, M., and Rees, G. (2001) Functional magnetic resonance imaging and evoked potential correlates of conscious and unconscious vision in parietal extinction patients. Neuroimage 14, S68-75.
12. Ehrsson, H. H., Spence, C., and Passingham, R. E. (2004) Th at's my hand! Activity in premotor cortex reflects feeling of ownership of a lim Science 305: 5685, 875-7.
13. Eriksson, J., Larsson, A., Riklund Ahlstrom, K., and Nyberg, L. (2004) Visual consciousness: dissociating the neural correlates of perceptual transitions from sustained perception with fMR Consciousness and Cognition 13: 1, 61-72.
14. Ffytche, D. H., Howard, R. J., Brammer, M. J., David, A., Woodruff, P., and Williams, S. (1998) The anatomy of conscious vision: an fMRI study of visual hallucination Nature Neuroscience 1: 8, 738-42.
15. Fourneret, P. and Jeannerod, M. (1998) Limited conscious monitoring of motor performance in normal subject Neuropsychologia 36: 11, 1133-40.
16. Goebel, R., Muckli, L., Zanella, F. E., Singer, W., and Stoerig, P. (2001) Sustained extrastriate cortical activation without visual awareness revealed by fMRI studies of hemianopic patients. Vision Research 41: 10-11, 1459-74.
17. Grill-Spector, K., Kushnir, T., Hendler, T., and Malach, R. (2000) The dynamics of object-selective activation correlate with recognition performance in human Nature Neuroscience 3: 8, 837-43.
18. Hannula, D. E., Simons, D. J., and Cohen, N. J. (2005) Imaging implicit perception: promise and pitfall Nature Review: Neuroscience 6: 3, 247-55.
19. Haynes, J. D. and Rees, G. (2005) Predicting the orientation of invisible stimuli from activity in human primary visual corte Nature Neuroscience 8: 5, 686-91.
20. Haynes, J. D., Deichmann, R., and Rees, G. (2005) Eye-specific suppression in human LGN reflects perceptual dominance during binocular rivalry Nature 438, 496-9.
21. Haynes, J. D., Driver, J., and Rees, G. (2005) Visibility reflects dynamic changes of effective connectivity between V1 and fusiform corte Neuron 46: 5, 811-21.
22. He, S., Cavanagh, P., and Intriligator, J. (1996) Attentional resolution and the locus of visual awarenes Nature 383: 6598, 334-7.
23. Hirsch, J., DeLaPaz, R. L., Relkin, N. R., Victor, J., Kim, K., Li, T. et al. (1995) Illusory contours activate specific regions in human visual cortex: evidence from functional magnetic resonance imagin Proceedings of the National Academy of Sciences 92: 14, 6469-73.
24. Holender, D. (1986) Semantic activation without conscious identification in dichotic listening, parafoveal vision, and visual masking: a survey and appraisal Behavioral and Brain Sciences 9, 1-66.
25. Jeannerod, M. (2003) The mechanism of self-recognition in humans. Behavioural Brain Research 142: 1-2, 1-15.
26. Joliot, M., Ribary, U., and Llinas, R. (1994) Human oscillatory brain activity near 40 Hz coexists with cognitive temporal binding. Proceedings of the National Academy of Sciences 91: 24, 11,748-51.
27. Kaernbach, C., Schroger, E., Jacobsen, T., and Roeber, U. (1999) Effects of consciousness on human brain waves following binocular rivalr NeuroReport 10: 4, 713-16.
28. Kjaer, T. W., Nowak, M., Kjaer, K. W., Lou, A. R., and Lou, H. C. (2001) Precuneus-prefrontal activity during awareness of visual verbal stimul Consciousness and Cognition 10: 3, 356-65.
29. Kleinschmidt, A., Buchel, C., Zeki, S., and Frackowiak, R. S. (1998) Human brain activity during spontaneously reversing perception of ambiguous figure Proceedings of the Royal Society B: Biological Sciences 265: 1413, 2427-33.
30. Kleiser, R., Wittsack, J., Niedeggen, M., Goebel, R., and Stoerig, P. (2001) Is V1 necessary for conscious vision in areas of relative cortical blindness? Neuroimage 13: 4, 654-61.
31. Kreiman, G., Fried, I., and Koch, C. (2002) Single-neuron correlates of subjective vision in the human medial temporal lob Proceedings of the National Academy of Sciences 99: 12, 8378-83.
32. Kreiman, G., Koch, C., and Fried, I. (2000a) Category-specific visual responses of single neurons in the human medial temporal lobe. Nature Neuroscience 3: 9, 946-53.
33. Kreiman, G., Koch, C., and Fried, I. (2000b) Imagery neurons in the human brain. Nature 408: 6810, 357-61.
34. Lau, H. C., Rogers, R. D., Haggard, P., and Passingham, R. E. (2004) Attention to intentio Science 303: 5661, 1208-10.
35. Laureys, S., Faymonville, M. E., Luxen, A., Lamy, M., Franck, G., and Maquet, P. (2000) Restoration of thalamocortical connectivity aft er recovery from persistent vegetative stat Lancet 355: 9217, 1790-1.
36. Laureys, S., Faymonville, M. E., Peigneux, P., Damas, P., Lambermont, B., Del Fiore, G. et al. (2002) Cortical processing of noxious somatosensory stimuli in the persistent vegetative stat Neuroimage 17: 2, 732-41.
37. Lee, H. W., Hong, S. B., Seo, D. W., Tae, W. S., and Hong, S. C. (2000) Mapping of functional organization in human visual cortex: electrical cortical stimulatio Neurology 54: 4, 849-54.
38. Lee, S. H., Blake, R., and Heeger, D. J. (2005) Traveling waves of activity in primary visual cortex during binocular rivalr Nature Neuroscience 8: 1, 22-3.
39. Lou, H. C., Kjaer, T. W., Friberg, L., Wildschiodtz, G., Holm, S., and Nowak, M. (1999) A 15O-H2O PET study of meditation and the resting state of normal consciousnes Human Brain Mapping 7: 2, 98-105.
40. Luck, S. J., Vogel, E. K., and Shapiro, K. L. (1996) Word meanings can be accessed but not reported during the attentional blin Nature 383: 6601, 616-18.
41. Lumer, E. D., Friston, K. J., and Rees, G. (1998) Neural correlates of perceptual rivalry in the human brai Science 280: 5371, 1930-4.
42. Luu, P., Flaisch, T., and Tucker, D. M. (2000) Medial frontal cortex in action monitorin Journal of Neuroscience 20: 1, 464-69.
43. McGonigle, D. J., Hanninen, R., Salenius, S., Hari, R., Frackowiak, R. S., and Frith, C. D. (2002) Whose arm is it anyway? An fMRI case study of supernumerary phantom limb. Brain, 125 (Pt 6), 1265-74.
44. Marcel, A. J. (1983) Conscious and unconscious perception: experiments on visual masking and word recognitio Cognitive Psychology 15: 2, 197-237.
45. Marois, R., Chun, M. M., and Gore, J. C. (2000) Neural correlates of the attentional blink Neuron 28: 1 299-308.
46. Marois, R., Yi, D. J., and Chun, M. M. (2004) The neural fate of consciously perceived and missed events in the attentional blink Neuron 41: 3 465-72.
47. Morris, J. S., Ohman, A., and Dolan, R. J. (1999) A subcortical pathway to the right amygdala mediating "unseen" fear Proceedings of the National Academy of Sciences 96: 4 1680-5.
48. Moutoussis, K. and Zeki, S. (2002) The relationship between cortical activation and perception investigated with invisible stimuli Proceedings of the National Academy of Sciences 99: 14 9527-32.
49. Naccache, L. and Dehaene, S. (2001) The priming method: imaging unconscious repetition priming reveals an abstract representation of number in the parietal lobes Cerebral Cortex 11: 10 966-74.
50. Naccache, L., Gaillard, R., Adam, C., Hasboun, D., Clemenceau, S., Baulac, M. et al. (2005) A direct intracranial record of emotions evoked by subliminal words Proceedings of the National Academy of Sciences 102: 21 7713-17.
51. Niedeggen, M., Wichmann, P., and Stoerig, P. (2001) Change blindness and time to consciousness European Journal of Neuroscience 14: 10 1719-26.
52. O'Craven, K. M. and Kanwisher, N. (2000) Mental imagery of faces and places activates corresponding stimulus-specific brain regions Journal of Cognitive Neuroscience 12: 6 1013-23.
53. Ojanen, V., Revonsuo, A., and Sams, M. (2003) Visual awareness of low-contrast stimuli is reflected in event-related brain potentials Psychophysiology 40: 2 192-7.
54. Pascual-Leone, A. and Walsh, V. (2001) Fast backprojections from the motion to the primary visual area necessary for visual awareness Science 292: 5516 510-12.
55. Pasley, B. N., Mayes, L. C., and Schultz, R. T. (2004) Subcortical discrimination of unperceived objects during binocular rivalry Neuron 42: 1 163-72.
56. Pessoa, L. and Ungerleider, L. G. (2004) Neural correlates of change detection and change blindness in a working memory task Cerebral Cortex 14: 5 511-20.
57. Pins, D. and Ffytche, D. (2003) The neural correlates of conscious vision Cerebral Cortex 13: 5 461-74.
58. Pisella, L., Grea, H., Tilikete, C., Vighetto, A., Desmurget, M., Rode, G. et al. (2000) An "automatic pilot" for the hand in human posterior parietal cortex: toward reinterpreting optic ataxia Nature Neuroscience 3: 7 729-36.
59. Polonsky, A., Blake, R., Braun, J., and Heeger, D. J. (2000) Neuronal activity in human primary visual cortex correlates with perception during binocular rivalry Nature Neuroscience 3: 11 1153-9.
60. Portas, C. M., Krakow, K., Allen, P., Josephs, O., Armony, J. L., and Frith, C. D. (2000) Auditory processing across the sleep-wake cycle: simultaneous EEG and fMRI monitoring in humans Neuron 28: 3 991-9.
61. Portas, C. M., Strange, B. A., Friston, K. J., Dolan, R. J., and Frith, C. D. (2000) How does the brain sustain a visual percept? Proceedings of the Royal Society B: Biological Sciences 267: 1446, 845-50.
62. Rees, G., Frith, C. D., and Lavie, N. (1997) Modulating irrelevant motion perception by varying attentional load in an unrelated task Science 278: 5343 1616-19.
63. Rees, G., Russell, C., Frith, C. D., and Driver, J. (1999) Inattentional blindness versus inattentional amnesia for fixated but ignored words Science 286: 5449 2504-7.
64. Ress, D., and Heeger, D. J. (2003) Neuronal correlates of perception in early visual cortex Nature Neuro science 6: 4 414-20.
65. Ro, T., Breitmeyer, B., Burton, P., Singhal, N. S., and Lane, D. (2003) Feedback contributions to visual awareness in human occipital cortex Current Biology 13: 12 1038-41.
66. Rodriguez, E., George, N., Lachaux, J. P., Martinerie, J., Renault, B., and Varela, F. J. (1999) Perception's shadow: long-distance synchronization of human brain activity Nature 397: 6718 430-3.
67. Ruby, P. and Decety, J. (2001) Effect of subjective perspective taking during simulation of action: a PET investigation of agency Nature Neuroscience 4: 5 546-50.
68. Sakai, K., Watanabe, E., Onodera, Y., Uchida, I., Kato, H., Yamamoto, E. et al. (1995) Functional mapping of the human colour centre with echo-planar magnetic resonance imaging Proceedings of the Royal Society B: Biological Sciences 261: 1360 89-98.
69. Shafer, W. P. and Marcus, M. M. (1973) Self-stimulation alters human sensory brain responses Science 181, 175-7.
70. Silbersweig, D. A., Stern, E., Frith, C., Cahill, C., Holmes, A., Grootoonk, S. et al. (1995) A functional neuroanatomy of hallucinations in schizophrenia Nature 378: 6553 176-9.
71. Sirigu, A., Duhamel, J. R., Cohen, L., Pillon, B., Dubois, B., and Agid, Y. (1996) The mental representation of hand movements aft er parietal cortex damage Science 273: 5281 1564-8.
72. Sirigu, A., Daprati, E., Pradat-Diehl, P., Franck, N., and Jeannerod, M. (1999) Perception of selfgenerated movement following left parietal lesion. Brain 122 (Pt 10), 1867-74.
73. Sirigu, A., Daprati, E., Ciancia, S., Giraux, P., Nighoghossian, N., Posada, A. et al. (2004) Altered awareness of voluntary action aft er damage to the parietal cortex Nature Neuroscience 7: 1 80-4.
74. Slachevsky, A., Pillon, B., Fourneret, P., Pradat-Diehl, P., Jeannerod, M., and Dubois, B. (2001) Preserved adjustment but impaired awareness in a sensory-motor conflict following prefrontal lesions Journal of Cognitive Neuroscience 13: 3 332-40.
75. Summerfield, C., Jack, A. I., and Burgess, A. P. (2002) Induced gamma activity is associated with conscious awareness of pattern masked nouns International Journal of Psychophysiology 44: 2 93-100.
76. Tong, F. and Engel, S. A. (2001) Interocular rivalry revealed in the human cortical blind-spot representation Nature 411: 6834 195-9.
77. Tong, F., Nakayama, K., Vaughan, J. T., and Kanwisher, N. (1998) Binocular rivalry and visual awareness in human extrastriate cortex Neuron 21: 4 753-9.
78. Tononi, G., Srinivasan, R., Russell, D. P., and Edelman, G. M. (1998) Investigating neural correlates of conscious perception by frequency-tagged neuromagnetic responses Proceedings of the National Academy of Sciences 95: 6 3198-203.
79. Tootell, R. B., Reppas, J. B., Dale, A. M., Look, R. B., Sereno, M. I., Malach, R. et al. (1995) Visual motion aft ereffect in human cortical area MT revealed by functional magnetic resonance imaging Nature 375: 6527 139-41.
80. Valenza, N., Seghier, M. L., Schwartz, S., Lazeyras, F., and Vuilleumier, P. (2004) Tactile awareness and limb position in neglect: functional magnetic resonance imaging Annals of Neurology 55: 1 139-43.
81. Vanni, S., Revonsuo, A., and Hari, R. (1997) Modulation of the parieto-occipital alpha rhythm during object detection Journal of Neuroscience 17: 18 7141-7.
82. Vanni, S., Revonsuo, A., Saarinen, J., and Hari, R. (1996) Visual awareness of objects correlates with activity of right occipital cortex NeuroReport 8: 1 183-6.
83. Vuilleumier, P., Armony, J. L., Clarke, K., Husain, M., Driver, J., and Dolan, R. J. (2002) Neural response to emotional faces with and without awareness: event-related fMRI in a parietal patient with visual extinction and spatial neglect Neuropsychologia 40: 12 2156-66.
84. Weiller, C., Juptner, M., Fellows, S., Rijntjes, M., Leonhardt, G., Kiebel, S. et al. (1996) Brain representation of active and passive movements Neuroimage 4: 2 105-10.
85. Zeki, S. and Bartels, A. (1999) Toward a theory of visual consciousness Consciousness and Cognition 8: 2 225-59.
86. Zeki, S., Watson, J. D., and Frackowiak, R. S. (1993) Going beyond the information given: the relation of illusory visual motion to brain activity Proceedings of the Royal Society B: Biological Sciences 252: 1335 215-22.