Topical anaesthesia and intravenous cannulation success in paediatric patients: A randomized double-blind trial

British Journal of Anaesthesia

Volumn 100, Issue 4, 2008, Pages 521-524

  Arendts, G ^a   Stevens, M ^a   Fry, M ^a  

^a ST GEORGE HOSPITAL   (Australia)

Author keywords

Anaesthetics local, EMLA; Anaesthetics local, tetracaine; Veins, cannulation

Indexed keywords

ANGEL; EMLA; TETRACAINE; ANESTHETIC AGENT; LIDOCAINE; LOCAL ANESTHETIC AGENT; PRILOCAINE;

ARTICLE; BLISTER; CANNULATION; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; ERYTHEMA; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PEDIATRIC ANESTHESIA; PRIORITY JOURNAL; PRURITUS; RANDOMIZED CONTROLLED TRIAL; TERTIARY HEALTH CARE; TOPICAL ANESTHESIA; UNSPECIFIED SIDE EFFECT; URTICARIA; CATHETERIZATION; INFANT; LOCAL ANESTHESIA; METHODOLOGY; PRESCHOOL CHILD;

ANESTHESIA, LOCAL; ANESTHETICS, COMBINED; ANESTHETICS, LOCAL; CATHETERIZATION, PERIPHERAL; CHILD; CHILD, PRESCHOOL; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INFANT; LIDOCAINE; MALE; PRILOCAINE; TETRACAINE;

EID: 41949110168     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aen003     Document Type: Article

References (17)

1. Hallen B, Olsson GL, Uppfeldt A. Pain-free venepuncture. Effect of timing of application of local anaesthetic cream. Anaesthesia 1984; 39: 969-72
2. Hopkins CS, Buckley CJ, Bush GH. Pain-free injection in infants. Use of a lignocaine-prilocaine cream to prevent pain at intravenous induction of general anaesthesia in 1-5-year-old children. Anaesthesia 1988; 43: 198-201
3. Cordoni A, Cordoni LE. Eutectic mixture of local anesthetics reduces pain during intravenous catheter insertion in the pediatric patient. Clin J Pain 2001; 17: 115-8
4. Taddio A, Gurguis M, Koren G. Lidocaine-prilocaine cream versus tetracaine gel for procedural pain in children. Ann Pharmacother 2002; 36: 687-92
5. Molodecka J, Stenhouse C, Jones JM, Tomlinson A. Comparison of percutaneous anaesthesia for venous cannulation after topical application of either amethocaine or EMLA cream. Br J Anaesth 1994; 72: 174-6
6. Woolfson AD, McCafferty DF, McClelland KH, Boston V. Concentration- response analysis of percutaneous local anaesthetic formulations. Br J Anaesth 1988; 61: 589-92
7. Woolfson AD, McCafferty DF, Boston V. Clinical experiences with a novel percutaneous amethocaine preparation: prevention of pain due to venepuncture in children. Br J Clin Pharmacol 1990; 30: 273-9
8. Maunuksela EL, Korpela R. Double-blind evaluation of a lignocaine-prilocaine cream (EMLA) in children: effect on the pain associated with venous cannulation. Br J Anaesth 1986; 58: 1242-5
9. McCafferty DF, Woolfson AD, Boston V. In vivo assessment of percutaneous local anaesthetic preparations. Br J Anaesth 1989; 62: 17-21
10. Doyle E, Freeman J, Irn NT, Morton NS. An evaluation of a new self-adhesive patch preparation of amethocaine for topical anaesthesia prior to venous cannulation in children. Anaesthesia 1993; 48: 1050-2
11. Choy L, Collier J, Watson AR. Comparison of lignocaine-prilocaine cream and amethocaine gel for local analgesia before venipuncture in children. Acta Paediatr 2004; 88: 961-4
12. Rogers TL, Ostrow CL. The use of EMLA cream to decrease venipuncture pain in children. J Pediatr Nurs 2004; 19: 33-9
13. Romsing J, Henneberg SW, Walther-Larsen S, Kjeldsen C. Tetracaine gel vs EMLA cream for percutaneous anaesthesia in children. Br J Anaesth 1999; 82: 637-8
14. Lander JA, Weltman BJ, So SS. EMLA and amethocaine for reduction of children's pain associated with needle insertion. Cochrane Database Syst Rev 2006; 3: CD004236
15. Browne J, Awad I, Plant R, McAdoo J, Shorten G. Topical amethocaine (Ametop) is superior to EMLA for intravenous cannulation. Can J Anaesth 1999; 46: 1014-8
16. Bjerring P, Andersen PH, Arendt-Nielsen L. Vascular response of human skin after analgesia with EMLA cream. Br J Anaesth 1989; 63: 655-60
17. Ashley EMC, Quick DGC, El-Behesey B, Bromley LM. A comparison of the vasodilatation produced by two topical anaesthetics. Anaesthesia 1999; 54: 466-9