Monitoring of fosinopril sodium impurities by liquid chromatography-mass spectrometry including the neural networks in method evaluation

Journal of Chromatography A

Volumn 1189, Issue 1-2, 2008, Pages 366-373

  Jancic B ^a   Medenica, M ^b   Ivanovic D ^a   Jankovic S ^c   Malenovic A ^a  

^a Institute of Pharmaceutical Chemistry and Drug Analysis   (Serbia)

^b Institute of General and Physical Chemistry   (Serbia)

^c INSTITUTE OF MEAT HYGIENE AND TECHNOLOGY   (Serbia)

Author keywords

Artificial neural networks; Forced degradation studies; Fosinopril sodium; Impurity profiling; MS detection

Indexed keywords

DRUG PRODUCTS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NEURAL NETWORKS; SODIUM COMPOUNDS;

FORCED DEGRADATION STUDIES; FOSINOPRIL SODIUM; IMPURITY PROFILING;

IMPURITIES;

ACETIC ACID; AMMONIUM ACETATE; BUFFER; FOSINOPRIL; FOSINOPRILAT; METHANOL;

ALGORITHM; ARTICLE; ARTIFICIAL NEURAL NETWORK; BACK PROPAGATION; CHEMICAL COMPOSITION; CONCENTRATION (PARAMETERS); DRUG DEGRADATION; DRUG IMPURITY; DRUG MONITORING; DRUG SCREENING; EVALUATION; EXPERIMENTAL DESIGN; FLOW RATE; HUMAN; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PARTICLE SIZE; PRIORITY JOURNAL; VALIDATION PROCESS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FOSINOPRIL; MOLECULAR STRUCTURE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 41949101118     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2007.11.076     Document Type: Article

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