Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD

EMBO Journal

Volumn 27, Issue 7, 2008, Pages 1172-1181

  Nowotny, Marcin ^a,c   Cerritelli, Susana M ^b   Ghirlando, Rodolfo ^a   Gaidamakov, Sergei A ^b   Crouch, Robert J ^b   Yang, Wei ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c INTERNATIONAL INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Poland)

Author keywords

dsRNA; Processivity; RNA DNA hybrid; RNase H; Specificity

Indexed keywords

DEOXYRIBOSE; NUCLEIC ACID; RIBONUCLEASE H;

ALPHA HELIX; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA BINDING; DNA RNA HYBRIDIZATION; ENZYME ACTIVITY; ENZYME ANALYSIS; GENE STRUCTURE; HUMAN; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; RNA BINDING;

AMINO ACID SEQUENCE; ANIMALS; BASE PAIRING; CRYSTALLOGRAPHY, X-RAY; DNA; HUMANS; MICE; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NUCLEIC ACID HETERODUPLEXES; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RIBONUCLEASE H; RNA; SUBSTRATE SPECIFICITY;

EID: 41949083183     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2008.44     Document Type: Article

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