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Miguet L, Pacaud K, Felden C, Hugel B, Martinez MC, Freyssinet J-M, Herbrecht R, Potier N, van Dorsselaer A, Mauvieux L: Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization. Proteomics (2006) 6(1):153-171. • Many pathology-associated membrane proteins were identified in malignant lymphoid cells.
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Miguet L, Pacaud K, Felden C, Hugel B, Martinez MC, Freyssinet J-M, Herbrecht R, Potier N, van Dorsselaer A, Mauvieux L: Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization. Proteomics (2006) 6(1):153-171. • Many pathology-associated membrane proteins were identified in malignant lymphoid cells.
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40
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Malaria vaccines: Are we getting closer?
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Epstein JE, Giersing B, Mullen G, Moorthy V, Richie TL: Malaria vaccines: Are we getting closer? Curr Opin Mol Ther (2007) 9(1):12-24.
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41
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Invasion of red blood cells by malaria parasites
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The molecular mechanism of red cell invasion by malaria parasites is described. Out of 48 important parasite proteins, 24 are membrane or peripheral surface proteins, •
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Cowman AF, Crabb BS: Invasion of red blood cells by malaria parasites. Cell (2006) 124(4):755-766. • The molecular mechanism of red cell invasion by malaria parasites is described. Out of 48 important parasite proteins, 24 are membrane or peripheral surface proteins.
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Cell
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Johnson JR, Florens R, Carucci DJ, Yates JR 3rd: Proteomics in malaria. J Proteome Res (2004) 3(2):296-306.
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J Proteome Res
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Johnson, J.R.1
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43
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Gilson PR, Nebl T, Vukcevic D, Moritz RL, Sargaent T, Speed TP, Schofield L, Crabb BS: Identification and stoichiometry of glycosylphosphatidylinositol-anchored membrane proteins of human malaria parasite Plasmodium falciparum. Mol Cell Proteomics (2006) 5(7):1286-1299. • Proteomic analysis identified GPI-anchoring of surface proteins in the malaria parasite and computer software predicted additional GPI-anchored proteins
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Gilson PR, Nebl T, Vukcevic D, Moritz RL, Sargaent T, Speed TP, Schofield L, Crabb BS: Identification and stoichiometry of glycosylphosphatidylinositol-anchored membrane proteins of human malaria parasite Plasmodium falciparum. Mol Cell Proteomics (2006) 5(7):1286-1299. • Proteomic analysis identified GPI-anchoring of surface proteins in the malaria parasite and computer software predicted additional GPI-anchored proteins.
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44
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22144496081
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Immunogenic membrane-associated proteins of Mycobacterium tuberculosis revealed by proteomics
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Sinha S, Kosalai K, Arora S, Namane A, Sharma P, Gaikwad AN, Brodin P, Cole ST: Immunogenic membrane-associated proteins of Mycobacterium tuberculosis revealed by proteomics. Microbiology (2005) 151(7):2411-2419.
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Sinha, S.1
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Brodin, P.7
Cole, S.T.8
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45
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33646266241
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Proteomics unique to intraphagosomally grown Mycobacterium tuberculosis
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Mattow J, Siejak F, Hagens K, Becher D, Albrecht D, Krah A, Schmidt F, Jungblut PR, Kaufmann SHE, Schaible UE: Proteomics unique to intraphagosomally grown Mycobacterium tuberculosis. Proteomics (2006) 6(8):2485-2494.
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46
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34249701192
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Comprehensive analysis of exported proteins from Mycobacterium tuberculosis H37Rv
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A proteomic analysis of secreted Mycobacterium proteins was conducted and a significant portion of the identified proteins were integral or plasma membrane-associated proteins, •
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Målen H, Berven FS, Fladmark KE, Wiker HG: Comprehensive analysis of exported proteins from Mycobacterium tuberculosis H37Rv. Proteomics (2007) 7(10):1702-1718. • A proteomic analysis of secreted Mycobacterium proteins was conducted and a significant portion of the identified proteins were integral or plasma membrane-associated proteins.
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Proteomics
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Målen, H.1
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47
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Identifying the membrane proteome of HIV-1 latently infected cells
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Berro R, de la Fuente C, Klase Z, Kehn K, Parvin L, Pumfery A, Abgottah E, Vertes A, Nekhai S, Kashanchi F: Identifying the membrane proteome of HIV-1 latently infected cells. J Biol Chem (2007) 282(11):8207-8218.
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J Biol Chem
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Abgottah, E.7
Vertes, A.8
Nekhai, S.9
Kashanchi, F.10
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48
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33846817305
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Identification of HLA class I-associated amino acid polymorphisms in the HIV-1C proteome
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Proteomic methods were used to demonstrate the potential of HIV to escape cytotoxic lymphocyte attack, •
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Boutwell CL, Essex M: Identification of HLA class I-associated amino acid polymorphisms in the HIV-1C proteome. AIDS Res Hum Retroviruses (2007) 23(1):165-174. • Proteomic methods were used to demonstrate the potential of HIV to escape cytotoxic lymphocyte attack.
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AIDS Res Hum Retroviruses
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Boutwell, C.L.1
Essex, M.2
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49
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33748300901
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Comparative immunoproteomics of identification and chracterization of virulence factors from Helicobacter pylori related to gastric cancer
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Surface proteins of H pylori were probed in serum samples of patients with gastric cancer. Co-chaperonin GroES was identified as a novel virulence factor associated with gastric cancer, •
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Lin YF, Wu MS, Chang CC, Lin SW, Lin JT, Sun YJ, Chen DS, Chow LP: Comparative immunoproteomics of identification and chracterization of virulence factors from Helicobacter pylori related to gastric cancer. Mol Cell Proteomics (2006) 5(8):1484-1496. • Surface proteins of H pylori were probed in serum samples of patients with gastric cancer. Co-chaperonin GroES was identified as a novel virulence factor associated with gastric cancer.
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Mol Cell Proteomics
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Lin, Y.F.1
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Chow, L.P.8
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50
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Modification of host lipid raft proteome upon hepatitis C virus replication
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Mannová P, Fang R, Wang H, Deng B, McIntosh MW, Hanash SM, Beretta L: Modification of host lipid raft proteome upon hepatitis C virus replication. Mol Cell Proteomics (2006) 5(12):2319-2325.
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Mol Cell Proteomics
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Mannová, P.1
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51
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A five-gene signature and clinical outcome in non-small-cell lung cancer
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Chen HY, Yu SL, Chen CH, Chang GC, Chen CY, Yuan A, Cheng CL, Wang CH, Terng HJ, Kao SF, Chan WK et al: A five-gene signature and clinical outcome in non-small-cell lung cancer. N Engl J Med (2007) 356(1):11-20.
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N Engl J Med
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Cheng, C.L.7
Wang, C.H.8
Terng, H.J.9
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N Engl J Med
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Mesothelin variant 1 is released from tumor cells as a diagnostic marker
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Hellstrom I, Raycraft J, Kanan S, Sardesai NY, Verch T, Yang Y, Hellstrom KE: Mesothelin variant 1 is released from tumor cells as a diagnostic marker. Cancer Epidemiol Biomarkers Prev (2006) 15(5):1014- 1020.
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Cancer Epidemiol Biomarkers Prev
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Hellstrom, I.1
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54
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B7-H4 is a novel membrane-bound protein and a candidate serum and tissue biomarker for ovarian cancer
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A sensitive mAb sandwich ELISA was developed to analyze levels of B7-H4 in serum, ascites fluids and tissue lysates, •
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Simon I, Zhuo S, Corral L, Diamandis EP, Sarno MJ, Wolfert RL, Kim NW: B7-H4 is a novel membrane-bound protein and a candidate serum and tissue biomarker for ovarian cancer. Cancer Res (2006) 66(3):1570- 1575. • A sensitive mAb sandwich ELISA was developed to analyze levels of B7-H4 in serum, ascites fluids and tissue lysates.
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Cancer Res
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Simon, I.1
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Kim, N.W.7
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55
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A proteomic approach to investigate potential biomarkers directed against membrane-associated breast cancer proteins
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Canelle L, Bousquet J, Pionneau C, Hardouin J, Choquet-Kastylevsky G, Joubert-Caron R, Caron M: A proteomic approach to investigate potential biomarkers directed against membrane-associated breast cancer proteins. Electrophoresis (2006) 27(8):1609-1616.
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Electrophoresis
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Caron, M.7
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56
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Distribution of GPR30, a seven membranespanning estrogen receptor, in primary breast cancer and its association with clinicopathologic determinations of tumor progression
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Filardo EJ, Graeber CT, Quinn JA, Resnick MB, Giri D, DeLellis RA, Steinhoff MM, Sabo E: Distribution of GPR30, a seven membranespanning estrogen receptor, in primary breast cancer and its association with clinicopathologic determinations of tumor progression. Clin Cancer Res (2006) 12(21):6359-6366.
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Clin Cancer Res
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Steinhoff, M.M.7
Sabo, E.8
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57
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Is prostate-specific membrane antigen a multifunctional protein?
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The structure and possible function(s) of PSMA, and its role as a potential target for prostate cancer therapy were discussed, •
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Rajasekaran AK, Anilkumar G, Christiansen JJ: Is prostate-specific membrane antigen a multifunctional protein? Am J Physiol Cell Physiol (2005) 288(5):C975-C981. • The structure and possible function(s) of PSMA, and its role as a potential target for prostate cancer therapy were discussed.
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Am J Physiol Cell Physiol
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Successful in vivo tumor targeting of prostate-specific membrane antigen with a highly efficient J591/PEI/DNA molecular conjugate
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Moffatt S, Papasakelariou C, Wiehle S, Cristiano R: Successful in vivo tumor targeting of prostate-specific membrane antigen with a highly efficient J591/PEI/DNA molecular conjugate. Gene Ther (2006) 13(9):761-772.
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Aptamer: Toxin conjugates that specifically target prostate tumor cells
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Chu TC, Marks JW 3rd, Lavery LA, Faulkner S, Rosenblum MG, Ellington AD, Levy M: Aptamer: Toxin conjugates that specifically target prostate tumor cells. Cancer Res (2006) 66(12):5989-5992.
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Cancer Res
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60
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Vascular targeted therapy with anti-prostate-specific membrane antigen monoclonal antibody J591 in advanced solid tumors
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Preliminary data demonstrated that the anti-PSMA antibody can be used as a potential vascular targeting agent, •
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Milowsky MI, Nanus DM, Kostakoglu L, Sheehan CE, Vallabhajosula S, Goldsmith SJ, Ross JS, Bander NH: Vascular targeted therapy with anti-prostate-specific membrane antigen monoclonal antibody J591 in advanced solid tumors. J Clin Oncol (2007) 25(5):540-547. • Preliminary data demonstrated that the anti-PSMA antibody can be used as a potential vascular targeting agent.
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J Clin Oncol
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Neri D, Bicknell R: Tumour vascular targeting. Nat Rev Cancer (2005) 5(6):436-446. • Tumor endothelial markers as putative targets for cancer treatment were described.
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62
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NGEP, a prostate-specific plasma membrane protein that promotes the association of LNCaP cells
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Das S, Hahn Y, Nagata S, Willingham MC, Bera TK, Lee B, Pastan I: NGEP, a prostate-specific plasma membrane protein that promotes the association of LNCaP cells. Cancer Res (2007) 67(4):1594-1601.
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Cancer Res
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63
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Oh P, Borgström P, Witkiewicz H, Li Y, Borgström BJ, Chrastina A, Iwata KR, Zinn KR, Baldwin R, Testa JE, Schnitzer JE: Live dynamic imaging of caveolae pumping targeted antibody rapidly and specifically across endothelium in the lung. Nat Biotechnol (2007) 25(3):327-337. • Fluorescently labeled antibodies against APP, a plasma membrane protein specific for the lung endothelium, were injected to target the lung caveolae. The antibodies were pumped from the blood into lung tissue within seconds.
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Oh P, Borgström P, Witkiewicz H, Li Y, Borgström BJ, Chrastina A, Iwata KR, Zinn KR, Baldwin R, Testa JE, Schnitzer JE: Live dynamic imaging of caveolae pumping targeted antibody rapidly and specifically across endothelium in the lung. Nat Biotechnol (2007) 25(3):327-337. • Fluorescently labeled antibodies against APP, a plasma membrane protein specific for the lung endothelium, were injected to target the lung caveolae. The antibodies were pumped from the blood into lung tissue within seconds.
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64
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Multiplex detection of surface molecules on colorectal cancers
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A thorough analysis of the surface antigens from different single cell populations isolated from colorectal cancers was conducted, •
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Ellmark P, Belov L, Huang P, Lee CS, Solomon MJ, Morgan DK, Christopherson RI: Multiplex detection of surface molecules on colorectal cancers. Proteomics (2006) 6(6):1791-1802. • A thorough analysis of the surface antigens from different single cell populations isolated from colorectal cancers was conducted.
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Proteomics
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Ellmark, P.1
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Detection and identification of heat shock protein 10 as a biomarker in colorectal cancer by protein profiling
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Melle C, Bogumil R, Ernst G, Schimmel B, Bleul A, von Eggeling F: Detection and identification of heat shock protein 10 as a biomarker in colorectal cancer by protein profiling. Proteomics (2006) 6(8):2600-2608.
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Proteomics
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66
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Cholangiocyte marker-positive and -negative fetal liver cells differ significantly in their ability to regenerate the livers of adult rats exposed to retrosine
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Different phenotypically defined subpopulations of fetal liver epithelial cells were isolated by use of an mAb directed against cell-surface developmental epitopes, •
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Simper-Ronan R, Brilliant K, Flanagan D, Carreiro M, Callanan H, Sabo E, Hixson DC: Cholangiocyte marker-positive and -negative fetal liver cells differ significantly in their ability to regenerate the livers of adult rats exposed to retrosine. Development (2006) 133(21):4269-4279. • Different phenotypically defined subpopulations of fetal liver epithelial cells were isolated by use of an mAb directed against cell-surface developmental epitopes.
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Development
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Simper-Ronan, R.1
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67
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Carcinoembryonic antigen-related cell adhesion molecule 1a-4L suppression of rat hepatocellular carcinomas
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Laurie NA, Comegys MM, Carreiro MP, Brown JF, Flanagan DL, Brilliant KE, Hixson DC: Carcinoembryonic antigen-related cell adhesion molecule 1a-4L suppression of rat hepatocellular carcinomas. Cancer Res (2005) 65(23):11010-11017.
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Cancer Res
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Brilliant, K.E.6
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68
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N Engl J Med
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High dynamic range characterization of the trauma patient plasma proteome
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An extensive reference database resource to aid investigation of biomarkers for trauma is described, •
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Liu T, Qian WT, Gritsenko MA, Xiao W, Moldawer LL, Kaushal A, Monroe ME, Varnum SM, Moore RJ, Purvine SO, Maier RV et al: High dynamic range characterization of the trauma patient plasma proteome. Mol Cell Proteomics (2006) 5(10):1899-1913. • An extensive reference database resource to aid investigation of biomarkers for trauma is described.
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Mol Cell Proteomics
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Liu, T.1
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71
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Aqueous two-phase partitioning for proteomic monitoring of cell surface biomarkers in human peripheral blood mononuclear cells
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Everberg H, Peterson R, Rak S, Tjerneld F, Emanuelsson C: Aqueous two-phase partitioning for proteomic monitoring of cell surface biomarkers in human peripheral blood mononuclear cells. J Proteome Res (2006) 5(5):1168-1175.
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J Proteome Res
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Circulating human monocytes in the acute coronary syndrome express a characteristic proteomic profile
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Barderas MG, Tunon J, Darde VM, De la Cuesta F, Jimenez-Nacher JJ, Tarin N, Lopez-Bescos L, Egido J, Vivanco F: Circulating human monocytes in the acute coronary syndrome express a characteristic proteomic profile. J Proteome Res (2007) 6(2):876-886.
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J Proteome Res
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Proteomics-based development of biomarkers in cardiovascular disease: Mechanistic, clinical and therapeutic insights
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Mayr M, Zhang J, Greene AS, Gutterman D, Perloff J, Ping P: Proteomics-based development of biomarkers in cardiovascular disease: Mechanistic, clinical and therapeutic insights. Mol Cell Proteomics (2006) 5(10):1853-1864.
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Mol Cell Proteomics
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Proteomic analysis of membrane microdomains derived from both failing and non-failing human hearts
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Banfi C, Brioschi M, Wait R, Begum S, Gianazza E, Fratto P, Polvani G, Vitali E, Parolari A, Mussoni L, Tremoli E: Proteomic analysis of membrane microdomains derived from both failing and non-failing human hearts. Proteomics (2006) 6(6):1976-1988.
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Proteomics
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75
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