Follicular fluid anti-Müllerian hormone and inhibin B concentrations: comparison between gonadotropin-releasing hormone (GnRH) agonist and GnRH antagonist cycles

Fertility and Sterility

Volumn 89, Issue 4, 2008, Pages 860-867

  Lee, Jung Ryeol ^a   Kim, Seok Hyun ^a   Kim, Sun Mie ^a   Jee, Byung Chul ^a   Ku, Seung Yup ^a   Suh, Chang Suk ^a   Choi, Young Min ^a   Kim, Jung Gu ^a   Moon, Shin Yong ^a  

^a Seoul National University   (South Korea)

Author keywords

Anti M llerian hormone; controlled ovarian hyperstimulation; follicular fluid; GnRH agonist; GnRH antagonist; inhibin B

Indexed keywords

CETRORELIX; CHORIONIC GONADOTROPIN; INHIBIN B; MUELLERIAN INHIBITING FACTOR; RECOMBINANT FOLLITROPIN; TRIPTORELIN;

ADULT; ARTICLE; CONTROLLED STUDY; DRUG DOSE REDUCTION; DRUG INHIBITION; FEMALE; HUMAN; IMPLANTATION; MAJOR CLINICAL STUDY; OOCYTE; OOCYTE RETRIEVAL; OUTCOME ASSESSMENT; OVARY FOLLICLE FLUID; OVARY HYPERSTIMULATION; PREGNANCY OUTCOME; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL;

ADULT; AGE FACTORS; ANTI-MULLERIAN HORMONE; BIOLOGICAL MARKERS; CHORIONIC GONADOTROPIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; EMBRYO IMPLANTATION; ESTRADIOL; FEMALE; FERTILITY AGENTS, FEMALE; FERTILIZATION IN VITRO; FOLLICULAR FLUID; GONADOTROPIN-RELEASING HORMONE; HORMONE ANTAGONISTS; HUMANS; INFERTILITY, FEMALE; INHIBINS; OOCYTE RETRIEVAL; OVULATION INDUCTION; PREGNANCY; PREGNANCY RATE; PROGESTERONE; PROSPECTIVE STUDIES; TREATMENT OUTCOME; TRIPTORELIN;

EID: 41849112724     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2007.04.010     Document Type: Article

References (47)

1. de Vet A., Laven J.S., de Jong F.H., Themmen A.P., and Fauser B.C. Antimullerian hormone serum levels: a putative marker for ovarian aging. Fertil Steril 77 (2002) 357-362
2. van Rooij I.A., Broekmans F.J., Scheffer G.J., Looman C.W., Habbema J.D., de Jong F.H., et al. Serum antimullerian hormone levels best reflect the reproductive decline with age in normal women with proven fertility: a longitudinal study. Fertil Steril 83 (2005) 979-987
3. van Rooij I.A., Broekmans F.J., te Velde E.R., Fauser B.C., Bancsi L.F., de Jong F.H., et al. Serum anti-Mullerian hormone levels: a novel measure of ovarian reserve. Hum Reprod 17 (2002) 3065-3071
4. Seifer D.B., MacLaughlin D.T., Christian B.P., Feng B., and Shelden R.M. Early follicular serum mullerian-inhibiting substance levels are associated with ovarian response during assisted reproductive technology cycles. Fertil Steril 77 (2002) 468-471
5. Fanchin R., Schonauer L.M., Righini C., Frydman N., Frydman R., and Taieb J. Serum anti-Mullerian hormone dynamics during controlled ovarian hyperstimulation. Hum Reprod 18 (2003) 328-332
6. Hazout A., Bouchard P., Seifer D.B., Aussage P., Junca A.M., and Cohen-Bacrie P. Serum antimullerian hormone/mullerian-inhibiting substance appears to be a more discriminatory marker of assisted reproductive technology outcome than follicle-stimulating hormone, inhibin B, or estradiol. Fertil Steril 82 (2004) 1323-1329
7. Eldar-Geva T., Ben-Chetrit A., Spitz I.M., Rabinowitz R., Markowitz E., Mimoni T., et al. Dynamic assays of inhibin B, anti-Mullerian hormone and estradiol following FSH stimulation and ovarian ultrasonography as predictors of IVF outcome. Hum Reprod 20 (2005) 3178-3183
8. Durlinger A.L., Gruijters M.J., Kramer P., Karels B., Ingraham H.A., Nachtigal M.W., et al. Anti-Mullerian hormone inhibits initiation of primordial follicle growth in the mouse ovary. Endocrinology 143 (2002) 1076-1084
9. Durlinger A.L., Gruijters M.J., Kramer P., Karels B., Kumar T.R., Matzuk M.M., et al. Anti-Mullerian hormone attenuates the effects of FSH on follicle development in the mouse ovary. Endocrinology 142 (2001) 4891-4899
10. Josso N., Racine C., di Clemente N., Rey R., and Xavier F. The role of anti-Mullerian hormone in gonadal development. Mol Cell Endocrinol 145 (1998) 3-7
11. Seifer D.B., MacLaughlin D.T., Penzias A.S., Behrman H.R., Asmundson L., Donahoe P.K., et al. Gonadotropin-releasing hormone agonist-induced differences in granulosa cell cycle kinetics are associated with alterations in follicular fluid mullerian-inhibiting substance and androgen content. J Clin Endocrinol Metab 76 (1993) 711-714
12. Laven J.S., and Fauser B.C. Inhibins and adult ovarian function. Mol Cell Endocrinol 225 (2004) 37-44
13. Welt C.K., McNicholl D.J., Taylor A.E., and Hall J.E. Female reproductive aging is marked by decreased secretion of dimeric inhibin. J Clin Endocrinol Metab 84 (1999) 105-111
14. Seifer D.B., Lambert-Messerlian G., Hogan J.W., Gardiner A.C., Blazar A.S., and Berk C.A. Day 3 serum inhibin-B is predictive of assisted reproductive technologies outcome. Fertil Steril 67 (1997) 110-114
15. Seifer D.B., Scott Jr. R.T., Bergh P.A., Abrogast L.K., Friedman C.I., Mack C.K., et al. Women with declining ovarian reserve may demonstrate a decrease in day 3 serum inhibin B before a rise in day 3 follicle-stimulating hormone. Fertil Steril 72 (1999) 63-65
16. Al-Inany H., and Aboulghar M. GnRH antagonist in assisted reproduction: a Cochrane review. Hum Reprod 17 (2002) 874-885
17. Al-Inany H., Abou-Setta A., and Aboulghar M. Gonadotrophin-releasing hormone antagonists for assisted conception. Cochrane Database Syst Rev 3 (2006) CD001750
18. Roulier R., Chabert-Orsini V., Sitri M.C., Barry B., and Terriou P. Depot GnRH agonist versus the single dose GnRH antagonist regimen (cetrorelix, 3 mg) in patients undergoing assisted reproduction treatment. Reprod Biomed Online 7 (2003) 185-189
19. Olivennes F., Belaisch-Allart J., Emperaire J.C., Dechaud H., Alvarez S., Moreau L., et al. Prospective, randomized, controlled study of in vitro fertilization-embryo transfer with a single dose of a luteinizing hormone-releasing hormone (LH-RH) antagonist (cetrorelix) or a depot formula of an LH-RH agonist (triptorelin). Fertil Steril 73 (2000) 314-320
20. Albano C., Felberbaum R.E., Smitz J., Riethmuller-Winzen H., Engel J., Diedrich K., et al. Ovarian stimulation with HMG: results of a prospective randomized phase III European study comparing the luteinizing hormone-releasing hormone (LHRH)-antagonist cetrorelix and the LHRH-agonist buserelin. European Cetrorelix Study Group. Hum Reprod 15 (2000) 526-531
21. Lin Y., Kahn J.A., and Hillensjo T. Is there a difference in the function of granulosa-luteal cells in patients undergoing in-vitro fertilization either with gonadotrophin-releasing hormone agonist or gonadotrophin-releasing hormone antagonist?. Hum Reprod 14 (1999) 885-888
22. Chang C.L., Wang T.H., Horng S.G., Wu H.M., Wang H.S., and Soong Y.K. The concentration of inhibin B in follicular fluid: relation to oocyte maturation and embryo development. Hum Reprod 17 (2002) 1724-1728
23. Ocal P., Aydin S., Cepni I., Idil S., Idil M., Uzun H., et al. Follicular fluid concentrations of vascular endothelial growth factor, inhibin A and inhibin B in IVF cycles: are they markers for ovarian response and pregnancy outcome?. Eur J Obstet Gynecol Reprod Biol 115 (2004) 194-199
24. Fanchin R., Louafi N., Mendez Lozano D.H., Frydman N., Frydman R., and Taieb J. Per-follicle measurements indicate that anti-mullerian hormone secretion is modulated by the extent of follicular development and luteinization and may reflect qualitatively the ovarian follicular status. Fertil Steril 84 (2005) 167-173
25. The Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod 19 (2004) 41-47
26. Kakar S.S., Musgrove L.C., Devor D.C., Sellers J.C., and Neill J.D. Cloning, sequencing, and expression of human gonadotropin releasing hormone (GnRH) receptor. Biochem Biophys Res Commun 189 (1992) 289-295
27. Emons G., Schroder B., Ortmann O., Westphalen S., Schulz K.D., and Schally A.V. High affinity binding and direct antiproliferative effects of luteinizing hormone-releasing hormone analogs in human endometrial cancer cell lines. J Clin Endocrinol Metab 77 (1993) 1458-1464
28. Chegini N., Rong H., Dou Q., Kipersztok S., and Williams R.S. Gonadotropin-releasing hormone (GnRH) and GnRH receptor gene expression in human myometrium and leiomyomata and the direct action of GnRH analogs on myometrial smooth muscle cells and interaction with ovarian steroids in vitro. J Clin Endocrinol Metab 81 (1996) 3215-3221
29. Ortmann O., and Diedrich K. Pituitary and extrapituitary actions of gonadotrophin-releasing hormone and its analogues. Hum Reprod 14 Suppl 1 (1999) 194-206
30. Casan E.M., Raga F., and Polan M.L. GnRH mRNA and protein expression in human preimplantation embryos. Mol Hum Reprod 5 (1999) 234-239
31. Brus L., Lambalk C.B., de Koning J., Helder M.N., Janssens R.M., and Schoemaker J. Specific gonadotrophin-releasing hormone analogue binding predominantly in human luteinized follicular aspirates and not in human pre-ovulatory follicles. Hum Reprod 12 (1997) 769-773
32. Minaretzis D., Jakubowski M., Mortola J.F., and Pavlou S.N. Gonadotropin-releasing hormone receptor gene expression in human ovary and granulosa-lutein cells. J Clin Endocrinol Metab 80 (1995) 430-434
33. Nathwani P.S., Kang S.K., Cheng K.W., Choi K.C., and Leung P.C. Regulation of gonadotropin-releasing hormone and its receptor gene expression by 17beta-estradiol in cultured human granulosa-luteal cells. Endocrinology 141 (2000) 1754-1763
34. Hernandez E.R. Embryo implantation and GnRH antagonists: embryo implantation: the Rubicon for GnRH antagonists. Hum Reprod 15 (2000) 1211-1216
35. Ortmann O., Weiss J.M., and Diedrich K. Embryo implantation and GnRH antagonists: ovarian actions of GnRH antagonists. Hum Reprod 16 (2001) 608-611
36. Weiss J.M., Oltmanns K., Gurke E.M., Polack S., Eick F., Felberbaum R., et al. Actions of gonadotropin-releasing hormone antagonists on steroidogenesis in human granulosa lutein cells. Eur J Endocrinol 144 (2001) 677-685
37. Weiss J.M., Krautmacher B., Polack S., Diedrich K., and Ortmann O. Actions of GnRH antagonists on IGF-II, IGF-binding protein-2 and pregnancy-associated plasma protein-A in human granulosa-lutein cells. Eur J Endocrinol 149 (2003) 31-37
38. Asimakopoulos B., Schopper B., Dawson A., Caglar G.S., Vakalopoulos I., Al-Hasani S., et al. IGF-I and epidermal growth factor levels in follicular fluid of women undergoing controlled ovarian hyperstimulation using the multidose GnRH-antagonist protocol or the long GnRH-agonist protocol. J Endocrinol Invest 29 (2006) RC5-RC8
39. Choi Y.S., Ku S.Y., Jee B.C., Suh C.S., Choi Y.M., Kim J.G., et al. Comparison of follicular fluid IGF-I, IGF-II, IGFBP-3, IGFBP-4 and PAPP-A concentrations and their ratios between GnRH agonist and GnRH antagonist protocols for controlled ovarian stimulation in IVF-embryo transfer patients. Hum Reprod 21 (2006) 2015-2021
40. Asimakopoulos B., Nikolettos N., Nehls B., Diedrich K., Al-Hasani S., and Metzen E. Gonadotropin-releasing hormone antagonists do not influence the secretion of steroid hormones but affect the secretion of vascular endothelial growth factor from human granulosa luteinized cell cultures. Fertil Steril 86 (2006) 636-641
41. Cunha-Filho J.S., Lemos N., Stein N., Laranjeira A., and Passos E.P. Vascular endothelial growth factor and inhibin A in follicular fluid of infertile patients who underwent in vitro fertilization with a gonadotropin-releasing hormone antagonist. Fertil Steril 83 (2005) 902-907
42. Asimakopoulos B., Koster F., Felberbaum R., Al-Hasani S., Diedrich K., and Nikolettos N. Cytokine and hormonal profile in blood serum and follicular fluids during ovarian stimulation with the multidose antagonist or the long agonist protocol. Hum Reprod 21 (2006) 3091-3095
43. Laven J.S., Mulders A.G., Visser J.A., Themmen A.P., De Jong F.H., and Fauser B.C. Anti-Mullerian hormone serum concentrations in normoovulatory and anovulatory women of reproductive age. J Clin Endocrinol Metab 89 (2004) 318-323
44. Silberstein T., MacLaughlin D.T., Shai I., Trimarchi J.R., Lambert-Messerlian G., Seifer D.B., et al. Mullerian inhibiting substance levels at the time of HCG administration in IVF cycles predict both ovarian reserve and embryo morphology. Hum Reprod 21 (2006) 159-163
45. Ebner T., Sommergruber M., Moser M., Shebl O., Schreier-Lechner E., and Tews G. Basal level of anti-Mullerian hormone is associated with oocyte quality in stimulated cycles. Hum Reprod 21 (2006) 2022-2026
46. Lau C.P., Ledger W.L., Groome N.P., Barlow D.H., and Muttukrishna S. Dimeric inhibins and activin A in human follicular fluid and oocyte-cumulus culture medium. Hum Reprod 14 (1999) 2525-2530
47. Akande A.V., Asselin J., Keay S.D., Cahill D.J., Muttukrishna S., Groome N.P., et al. Inhibin A, inhibin B and activin A in follicular fluid of infertile women with tubal damage, unexplained infertility and endometriosis. Am J Reprod Immunol 43 (2000) 61-69