High glucose levels upregulate upstream stimulatory factor 2 gene transcription in mesangial cells

Journal of Cellular Biochemistry

Volumn 103, Issue 6, 2008, Pages 1952-1961

  Shi, Lihua ^a   Liu, Shu ^a   Nikolic, Dejan ^a   Wang, Shuxia ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Gene transcription; Glucose; Mesangial cells; USF2

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; GLUCOSE; MESSENGER RNA; SMALL INTERFERING RNA; UPSTREAM STIMULATORY FACTOR 2;

ANIMAL CELL; ARTICLE; CELL ASSAY; CELL STIMULATION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GLOMERULUS BASEMENT MEMBRANE; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN STABILITY; PROTEIN SYNTHESIS INHIBITION; RAT; SITE DIRECTED MUTAGENESIS; TRANSACTIVATION; TRANSCRIPTION INITIATION SITE; UPREGULATION;

ANIMALS; CELLS, CULTURED; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; GLUCOSE; MESANGIAL CELLS; PROMOTER REGIONS (GENETICS); RATS; TRANS-ACTIVATION (GENETICS); UP-REGULATION; UPSTREAM STIMULATORY FACTORS;

RATTUS;

EID: 41849108069     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21585     Document Type: Article

References (25)

1. Ahn S, Olive M, Aggarwal S, Krylov D, Ginty DD, Vinson C. 1998. A dominant-negative inhibitor of CREB reveals that it is a general mediator of stimulus-dependent transcription of c-fos. Mol Cell Biol 18:967-977.
2. Bidder M, Shao JS, Charlton-Kachigian N, Loewy AP, Semenkovich CF, Towler DA. 2002. Osteopontin transcription in aortic vascular smooth muscle cells is controlled by glucose-regulated upstream stimulatory factor and activator protein-1 activities. J Biol Chem 277:44485-44496.
3. Bloomgarden ZT. 2005. Diabetic nephropathy. Diabetes Care 28:745-751.
4. Chen L, Shen YH, Wang X, Wang J, Gan Y, Chen N, Wang J, LeMaire SA, Coselli JS, Wang XL. 2006. Human prolyl-4-hydroxylase alpha(I) transcription is mediated by upstream stimulatory factors. J Biol Chem 281:10849-10855.
5. Corre S, Galibert MD. 2005. Upstream stimulating factors: Highly versatile stress-responsive transcription factors. Pigment Cell Res 18:337-348.
6. Ishimura E, Sterzel RB, Morii H, Kashgarian M. 1992. Extracellular matrix protein: Gene expression and synthesis in cultured rat mesangial cells. Nippon Jinzo Gakkai Shi 34:9-17.
7. Kingsley-Kallesen ML, Kelly D, Rizzino A. 1999. Transcriptional regulation of the transforming growth factor-beta2 promoter by cAMP-responsive element-binding protein (CREB) and activating transcription factor-1 (ATF-1) is modulated by protein kinases and the coactivators p300 and CREB-binding protein. J Biol Chem 274:34020-34028.
8. Kingsley-Kallesen M, Luster TA, Rizzino A. 2001. Transcriptional regulation of the transforming growth factor-beta2 gene in glioblastoma cells. In Vitro Cell Dev Biol Anim 37:684-690.
9. Nicolas G, Bennoun M, Devaux I, Beaumont C, Grandchamp B, Kahn A, Vaulont S. 2001. Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Proc Natl Acad Sci USA 98:8780-8785.
10. Poczatek MH, Hugo C, Darley-Usmar V, Murphy-Ullrich JE. 2000. Glucose stimulation of transforming growth factor-beta bioactivity in mesangial cells is mediated by thrombospondin-1. Am J Pathol 157:1353-1363.
11. Qian J, Kaytor EN, Towle HC, Olson LK. 1999. Upstream stimulatory factor regulates Pdx-1 gene expression in differentiated pancreatic beta-cells. Biochem J 341(Pt 2):315-322.
12. Rippe RA, Umezawa A, Kimball JP, Breindl M, Brenner DA. 1997. Binding of upstream stimulatory factor to an E-box in the 3-flanking region stimulates alpha1(I) collagen gene transcription. J Biol Chem 272:1753-1760.
13. Sawadogo M, Roeder RG. 1985. Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region. Cell 43:165-175.
14. Scholtz B, Kingsley-Kallesen M, Rizzino A. 1996. Transcription of the transforming growth factor-beta2 gene is dependent on an E-box located between an essential cAMP response element/activating transcription factor motif and the TATA box of the gene. J Biol Chem 271:32375-32380.
15. Sirito M, Lin Q, Maity T, Sawadogo M. 1994. Ubiquitous expression of the 43- and 44-kDa forms of transcription factor USF in mammalian cells. Nucleic Acids Res 22:427-433.
16. Skyler JS. 1996. Diabetic complications. The importance of glucose control. Endocrinol Metab Clin North Am 25:243-254.
17. Susztak K, Sharma K, Schiffer M, McCue P, Ciccone E, Bottinger EP. 2003. Genomic strategies for diabetic nephropathy. J Am Soc Nephrol 14:S271-S278.
18. Vallet VS, Henrion AA, Bucchini D, Casado M, Raymondjean M, Kahn A, Vaulont S. 1997. Glucose-dependent liver gene expression in upstream stimulatory factor 2-/- mice. J Biol Chem 272:21944-21949.
19. Vallet VS, Casado M, Henrion AA, Bucchini D, Raymondjean M, Kahn A, Vaulont S. 1998. Differential roles of upstream stimulatory factors 1 and 2 in the transcriptional response of liver genes to glucose. J Biol Chem 273:20175-20179.
20. Wang S, Shiva S, Poczatek MH, Darley-Usmar V, Murphy-Ullrich JE. 2002. Nitric oxide and cGMP-dependent protein kinase regulation of glucose-mediated thrombospondin 1-dependent transforming growth factor-beta activation in mesangial cells. J Biol Chem 277:9880-9888.
21. Wang S, Skorczewski J, Feng X, Mei L, Murphy-Ullrich JE. 2004. Glucose upregulates thrombospondin 1 gene transcription and transforming growth factor-beta activity through antagonism of cGMP-dependent protein kinase repression via upstream stimulatory factor 2. J Biol Chem 279:34311-34322 [Epub 2004 June 7].
22. Watson PA, Vinson C, Nesterova A, Reusch JE. 2002. Content and activity of cAMP response element-binding protein regulate platelet-derived growth factor receptor-alpha content in vascular smooth muscles. Endocrinology 143:2922-2929.
23. Weigert C, Brodbeck K, Sawadogo M, Haring HU, Schleicher ED. 2004a. Upstream stimulatory factor (USF) proteins induce human TGF-beta1 gene activation via the glucose-response element-1013/-1002 in mesangial cells: Upregulation of USF activity by the hexosamine biosynthetic pathway. J Biol Chem 279:15908-15915.
24. Weigert C, Brodbeck K, Sawadogo M, Haring HU, Schleicher ED. 2004b. USF proteins induce human TGF-beta1 gene activation via the glucose response element -1013/-1002 in mesangial cells - Upregulation of USF activity by the hexosamine biosynthetic pathway. J Biol Chem 2:2.
25. Zhu Y, Casado M, Vaulont S, Sharma K. 2005. Role of upstream stimulatory factors in regulation of renal transforming growth factor-beta1. Diabetes 54:1976-1984.