HERG K+ channel blockade by the novel antiviral drug sophocarpine

Biological and Pharmaceutical Bulletin

Volumn 31, Issue 4, 2008, Pages 627-632

  Zhao, Xue Ling ^a   Qi, Zhi Ping ^a   Fang, Cheng ^a   Chen, Ming Hong ^a   Lv, Yan Jie ^a   Li, Bao Xin ^a   Yang, Bao Feng ^a,b  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b State Province Key Laboratory of Biopharmaceutical Engineering   (China)

Author keywords

Human embryonic kidney cell; Human ether go go related gene; Immunofluorescence; Patch clamp; Sophocarpine; Western blot

Indexed keywords

ANTIVIRUS AGENT; POTASSIUM CHANNEL HERG; POTASSIUM ION; SOPHOCARPINE; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEK293; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; HEART REPOLARIZATION; HUMAN; HUMAN CELL; IC 50; IMMUNOFLUORESCENCE; KINETICS; MUSCLE ACTION POTENTIAL; PATCH CLAMP; POTASSIUM CURRENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; QT PROLONGATION; WESTERN BLOTTING;

ALKALOIDS; ANTIVIRAL AGENTS; BLOTTING, WESTERN; CELL LINE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ELECTROPHYSIOLOGY; ETHER-A-GO-GO POTASSIUM CHANNELS; FLUORESCENT ANTIBODY TECHNIQUE; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; HUMANS; KINETICS; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS;

EID: 41849101073     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.31.627     Document Type: Article

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