Morphological features of basal-like subtype invasive carcinoma of breast

Chinese Journal of Pathology

Volumn 37, Issue 2, 2008, Pages 83-87

  Gao, Lan Xiang ^a   Yang, Guang Zhi ^a   Ding, Hua Ye ^a   Li, Lin ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Breast neoplasms; Carcinoma, basal cell; Diagnosis; Immunophenotyping

Indexed keywords

BIOLOGICAL MARKER; CALPONIN; COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; CYTOKERATIN 14; CYTOKERATIN 18; CYTOKERATIN 5; CYTOKERATIN 6; CYTOKERATIN 8; EPIDERMAL GROWTH FACTOR RECEPTOR 2; MONOCLONAL ANTIBODY; PROTEIN P63; EPIDERMAL GROWTH FACTOR RECEPTOR; ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR; TUMOR MARKER;

ARTICLE; BREAST CARCINOMA; CANCER DIAGNOSIS; CELL GROWTH; CELL HYPERPLASIA; CELL STRUCTURE; GENE OVEREXPRESSION; GIANT CELL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; INVASIVE CARCINOMA; LYMPHOCYTIC INFILTRATION; LYMPHOID TISSUE; MORPHOLOGY; MYOEPITHELIUM; NECROSIS; NUCLEUS ACCUMBENS; PROTEIN EXPRESSION; STATISTICAL SIGNIFICANCE; TISSUE SECTION; TUMOR VOLUME; WORLD HEALTH ORGANIZATION; BASAL CELL CARCINOMA; BREAST NEOPLASMS; DEVICES; ECHOGRAPHY; FEMALE; GENETICS; MALE; MAMMOGRAPHY; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; PROGNOSIS; PROTO ONCOGENE; TUMOR INVASION;

BREAST NEOPLASMS; CARCINOMA, BASAL CELL; FEMALE; GENES, ERBB-2; HUMANS; IMMUNOHISTOCHEMISTRY; KERATIN-5; MAGNETIC RESONANCE IMAGING; MALE; MAMMOGRAPHY; NEOPLASM INVASIVENESS; PROGNOSIS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; TUMOR MARKERS, BIOLOGICAL; ULTRASONOGRAPHY; BIOMARKERS, TUMOR;

EID: 41849099998     PISSN: 05295807     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Finak G, Sadekova S, Pepin F, et al. Gene expression signatures of morphologically normal breast tissue identify basal-like tumors. Breast Cancer Res, 2006, 8(5):R58.
2. Perou CM, Sørlie T, Eisen MB, et al. Molecular portraits of human breast tumours. Nature, 2000, 406(6797):747-752.
3. Sørlie T, Perou CM, Tibshirani R, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A, 2001, 98(19):10869-10874.
4. Sørlie T, Tibshirani R, Parker J, et al. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci U S A, 2003, 100(14):8418-8423.
5. Sotiriou C, Neo SY, McShane LM, et al. Breast cancer classification and prognosis based on gene expression profiles from a population-based study. Proc Natl Acad Sci U S A, 2003, 100(18):10393-10398.
6. Nielsen TO, Hsu FD, Jensen K, et al. Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma. Clin Cancer Res, 2004, 10(16):5367-5374.
7. Chinese source
8. Fulford LG, Easton DF, Reis-Filho JS, et al. Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast. Histopathology, 2006, 49(1):22-34.
9. Reis-Filho JS, Milanezi F, Steele D, et al. Metaplastic breast carcinomas are basal-like tumours. Histopathology, 2006, 49(1):10-21.
10. Dunne B, Lee AH, Pinder SE, et al. An immunohistochemical study of metaplastic spindle cell carcinoma, phyllodes tumor and fibromatosis of the breast. Hum Pathol, 2003, 34(10):1009-1015.
11. Rakha EA, Putti TC, Abd EI-Rehim DM, et al. Morphological and immunophenotypic analysis of breast carcinomas with basal and myoepithelial differentiation. J Pathol, 2006, 280(4):495-506.
12. Tavassoli FA, Devilee P. World Health Organization classification of tumours. Pathology and genetics of tumours of the breast and female genital organs. Lyon: IAPC Press, 2003:13-59.
13. Allred DC, Harvey JM, Berardo M, et al. Prognostic and predictive factors in breast cancer by immunohistochemical analysis. Mod Pathol, 1998, 11(2):155-168.
14. Chinese source
15. Hicks DG, Short SM, Prescott NL, et al. Breast cancers with brain metastases are more likely to be estrogen receptor negative, express the basal cytokeratin CK5/6, and overexpress HER2 or EGFR. Am J Surg Pathol, 2006, 30(9):1079-1104.
16. Fulford LG, Reis-Filho JS, Ryder K, et al. Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival. Breast Cancer Res, 2007, 9(1):R4.
17. Tsuda H, Takarabe T, Hasegawa T, et al. Myoepithelial differentiation in high-grade invasive ductal carcinomas with large central acellular zones. Hum Pathol, 1999, 30(10):1134-1139.
18. Laakso M, Loman N, Borg A, et al. Cytokeratin 5/14-positive breast cancer: true basal phenotype confined to BRCA1 tumors. Mod Pathol, 2005, 18(10):1321-1328.
19. Matos I, Dufloth R, Alvarenga M, et al. p63, cytokeratin 5, and P-cadherin: three molecular markers to distinguish basal phenotype in breast carcinomas. Virchows Arch, 2005, 447(4):688-694.