Serine protease inhibitors N-α-tosyl-L-lysinyl-chloromethylketone (TLCK) and N-tosyl-L-phenylalaninyl-chloromethylketone (TPCK) are potent inhibitors of activated caspase proteases

Journal of Cellular Biochemistry

Volumn 103, Issue 5, 2008, Pages 1646-1656

  Frydrych, Ivo ^a   Mlejnek, Petr ^a  

^a PALACKÝ UNIVERSITY   (Czech Republic)

Author keywords

Apoptosis; Cell death; Mature caspases; Mitochondrial transmembrane potential; Serine protease inhibitors

Indexed keywords

6 N (3,3 DIMETHYLALLYL)ADENOSINE; CASPASE; CASPASE 3; CASPASE 6; CASPASE 7; ENZYME INHIBITOR; ETOPOSIDE; SERINE PROTEINASE INHIBITOR; STAUROSPORINE; TOSYLLYSYL CHLOROMETHYL KETONE; TOSYLPHENYLALANYL CHLOROMETHYL KETONE;

ARTICLE; CELL DEATH; CELL STRAIN HL 60; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL;

APOPTOSIS; CASPASES; HL-60 CELLS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; RECOMBINANT PROTEINS; SERINE PROTEINASE INHIBITORS; TOSYLLYSINE CHLOROMETHYL KETONE; TOSYLPHENYLALANYL CHLOROMETHYL KETONE;

MAMMALIA;

EID: 41749095635     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21550     Document Type: Article

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