Nullomers: Really a matter of natural selection?

PLoS ONE

Volumn 2, Issue 10, 2007, Pages

  Acquisti, Claudia ^a,b   Poste, George ^b   Curtiss, David ^a   Kumar, Sudhir ^a,b  

^a ARIZONA STATE UNIVERSITY   (United States)

^b ARIZONA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; DNA;

ARTICLE; CHIMPANZEE; COW; DNA SEQUENCE; DOG; GENE FREQUENCY; GENE MUTATION; HUMAN; HUMAN GENOME; MOLECULAR EVOLUTION; MUTANT; NATURAL SELECTION; NONHUMAN; NULLOMER; POPULATION; ANIMAL; CATTLE; CPG ISLAND; GENETIC SELECTION; GENETICS; GENOME; MOLECULAR GENETICS; MOUSE; MUTATION; NUCLEOTIDE SEQUENCE; PAN TROGLODYTES; SPECIES DIFFERENCE;

CANIS FAMILIARIS; PAN;

ANIMALS; BASE SEQUENCE; CATTLE; CPG ISLANDS; DNA; DOGS; EVOLUTION, MOLECULAR; GENOME; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; PAN TROGLODYTES; SELECTION (GENETICS); SPECIES SPECIFICITY;

EID: 41749091362     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0001022     Document Type: Article

References (9)

1. Hampikian G, Andersen T (2007) Absent sequences: nullomers and primes. Pacific Sym. on Biocomputing 12: 355-366.
2. Fofanov Y, Luo Y, Katili C, Wang J, Belosludtsev Y, et al. (2004) How independent are the appearances of n-mers in different genomes? Bioinformatics 20: 2421-2428.
3. Haubold B, Pierstorff N, Möller F, Wiehe T (2005) Genome comparison without alignment using shortest unique substrings. BMC Bioinformatics 6: 123.
4. Kidwell MG (2002) Transposable elements and the evolution of genome size in eukaryotes. Genetica 115: 49-63.
5. Geddes L (2007) The DNA so dangerous it does not exist. New Scientist 2585: 12.
6. Gentles AJ, Karlin S (2001) Genome-scale compositional comparisons in eukaryotes. Genome Res. 11: 5440-546.
7. Josse J, Kaiser AD, Kornberg A (1961) Enzymatic Synthesis of Deoxyribonucleic Acid. VIII. Frequencies of nearest neighbor base sequences in deoxyribonucleic acid. J. Biol. Chem. 236: 864-875.
8. Sved J, Bird A (1990) Ile expected equilibrium of the CpG dinucleotide in vertebrate genomes under a mutation model. Proc Natl Acad Sci U S A 87: 4692-4696.
9. Subramanian S, Kumar S (2003) Neutral substitutions occur at a faster rate in exons than in noncoding DNA in primate genomes. Genome Res. 13: 838-844.