A class of novel nitronyl nitroxide labeling basic and acidic amino acids: Synthesis, application for preparing ESR optionally labeling peptides, and bioactivity investigations

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 7, 2008, Pages 4019-4028

  Zhang, Jianwei ^a   Zhao, Ming ^a   Cui, Guohui ^a   Peng, Shiqi ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Basic and acidic amino acids; Incorporating; Label; Nitronyl nitroxide; Peptide

Indexed keywords

2 (4' HYDROXYL)PHENYL 4,4,5,5 TETRAMETHYLIMIDAZOLINE 3 OXIDE 1 OXYL; ACETYLSALICYLIC ACID; AMINO ACID DERIVATIVE; ARGINYLGLYCYLASPARTYLSERINE; ARGINYLGLYCYLASPARTYLVALINE; ASPARAGINYLSERINE; CARBOXYL GROUP; GLUTAMYLCYSTEINYLGLYCINE; GUANIDINE DERIVATIVE; IMIDAZOLINE DERIVATIVE; NITRIC OXIDE; NITRONYL NITROXIDE; NITROXIDE DERIVATIVE; OMEGA AMINO ACID; PROLYLARGINYLLYSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOASSAY; BLOOD CLOT LYSIS; CHEMICAL ANALYSIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG SCREENING; DRUG SYNTHESIS; ELECTRON SPIN RESONANCE; FIBRINOLYSIS; LABELING INDEX; MALE; NONHUMAN; PEPTIDE SYNTHESIS; RAT; STRUCTURE ACTIVITY RELATION; THROMBOCYTE AGGREGATION; THROMBOSIS;

AMINO ACIDS, ACIDIC; AMINO ACIDS, BASIC; ANIMALS; CYTOPROTECTION; ELECTRON SPIN RESONANCE SPECTROSCOPY; FIBRINOLYTIC AGENTS; FREE RADICALS; MOLECULAR STRUCTURE; NITROGEN OXIDES; PC12 CELLS; PEPTIDES; PLATELET AGGREGATION; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; VASODILATION;

RICE GALL DWARF VIRUS;

EID: 41649119547     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.01.022     Document Type: Article

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