Irinotecan+5-fluorouracil with concomitant pre-operative radiotherapy in locally advanced non-resectable rectal cancer: A phase I/II study

British Journal of Cancer

Volumn 98, Issue 7, 2008, Pages 1210-1216

  Iles, S M ^a   Gollins, S W ^b   Susnerwala, S ^c   Haylock, B ^d   Myint, S ^d   Biswas, A ^c   Swindell, R ^a   Levine, E ^a  

^a CHRISTIE HOSPITAL   (United Kingdom)

^b GLAN CLWYD HOSPITAL   (United Kingdom)

^c ROYAL PRESTON HOSPITAL   (United Kingdom)

^d CLATTERBRIDGE CENTRE FOR ONCOLOGY   (United Kingdom)

Author keywords

Chemotherapy; Combined modality; Irinotecan; Locally advanced; Radiation; Rectal cancer

Indexed keywords

FLUOROURACIL; IRINOTECAN;

ABDOMINAL CRAMP; ADULT; AGED; ARTICLE; CANCER CHEMOTHERAPY; CANCER GRADING; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CLINICAL ARTICLE; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; CONSTIPATION; CONTINUOUS INFUSION; CONTROLLED STUDY; DIARRHEA; DISEASE FREE SURVIVAL; DISEASE SEVERITY; DOSE RESPONSE; DRUG DOSE ESCALATION; DRUG DOSE REDUCTION; DRUG TOLERABILITY; DRUG WITHDRAWAL; FEMALE; FEVER; FOLLOW UP; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INFECTION; LETHARGY; MALE; MULTIMODALITY CANCER THERAPY; NEUTROPENIA; NUCLEAR MAGNETIC RESONANCE IMAGING; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; RADIATION DOSE; RECTUM CANCER; SKIN DISEASE; SKIN SORE; THORAX PAIN;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CAMPTOTHECIN; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; FEMALE; FLUOROURACIL; HUMANS; MALE; MAXIMUM TOLERATED DOSE; MIDDLE AGED; NEOADJUVANT THERAPY; RADIOTHERAPY DOSAGE; RADIOTHERAPY, ADJUVANT; RECTAL NEOPLASMS; SURVIVAL RATE;

EID: 41649110840     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6604292     Document Type: Article

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