Synthesis and antitubercular evaluation of N′-[(R)-(hydroxy, methoxy and ethoxy-substituted-phenyl) methylidene]isonicotinohydrazide derivatives

Letters in Drug Design and Discovery

Volumn 5, Issue 2, 2008, Pages 137-140

  Ferreira, Marcelle De L ^a   Cardoso, Laura N De F ^a   Gonçalves, Raoni S B ^a   Da Silva, Emerson T ^a   Lourenço, Maria Cristina S ^b   Vicente, Felipe R ^b   De Souza, Marcus V N ^a  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b Funda??o Oswaldo Cruz   (Brazil)

Author keywords

Alamar blue assay; Antimycobacterial activity; Isoniazid; Isonicotinohydrazides; Multidrug resistance; Tuberculosis

Indexed keywords

HYDRAZIDE DERIVATIVE; ISONIAZID; N' [(2 HYDROXY 3 METHOXYPHENYL)METHYLIDENE]ISONICOTINOHYDRAZIDE; N' [(2,3 DIMETHOXYPHENYL)METHYLIDENE]ISONICOTINOHYDRAZIDE; N' [(2,5 DIMETHOXYPHENYL)METHYLIDENE]ISONICOTINOHYDRAZIDE; N' [(2,6 DIMETHOXYPHENYL)METHYLIDENE]ISONICOTINOHYDRAZIDE; N' [(3 HYDROXY 4 METHOXYPHENYL)METHYLIDENE]ISONICOTINOHYDRAZIDE; N' [(3,4 DIHYDROXYPHENYL)METHYLIDENE]ISONICOTINOHYDRAZIDE; N' [(3,4 DIMETHOXYPHENYL)METHYLIDENE]ISONICOTINOHYDRAZIDE; N' [(3,4,5 TRIMETHOXYPHENYL)METHYLIDENE]ISONICOTINOHYDRAZIDE; N' [(3,5 DIMETHOXYPHENYL)METHYLIDENE]ISONICOTINOHYDRAZIDE; N' [(4 HYDROXYPHENYL)METHYLIDENE]ISONICOTINOHYDRAZIDE; RIFAMPICIN; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL;

EID: 41649110421     PISSN: 15701808     EISSN: None     Source Type: Journal    
DOI: 10.2174/157018008783928472     Document Type: Article

References (8)

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