Diagnosing the diagnosis: Why we must standardize the defining features of polycystic ovary syndrome

Annals of Clinical Biochemistry

Volumn 45, Issue 1, 2008, Pages 3-5

  Azziz, Ricardo ^a,b  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTENEDIONE; TESTOSTERONE;

CLINICAL FEATURE; CLINICAL PRACTICE; DISEASE ASSOCIATION; EDITORIAL; HUMAN; HYPERANDROGENISM; MASS SPECTROMETRY; MEDICAL RESEARCH; MENSTRUAL CYCLE; MORPHOLOGY; OLIGOMENORRHEA; OVARY INSUFFICIENCY; OVARY POLYCYSTIC DISEASE; OVULATION; PATIENT CARE; PHENOTYPE; PREVALENCE; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RISK FACTOR; SYMPTOM; VAGINA BLEEDING; CLASSIFICATION; FEMALE; NOTE;

FEMALE; HUMANS; POLYCYSTIC OVARY SYNDROME;

EID: 41649098712     PISSN: 00045632     EISSN: 00045632     Source Type: Journal    
DOI: 10.1258/acb.2007.007198     Document Type: Editorial

References (22)

1. Barth JH, Yasmin E, Balen AH. The diagnosis of polycystic ovary syndrome: the criteria are insufficiently robust for clinical research. Clin Endocrinol 2007;67:811-15
2. Azziz R, Marin C, Hoq L, Badamgarav E, Song P. Health care-related economic burden of the polycystic ovary syndrome during the reproductive life span. J Clin Endocrinol Metab 2005;90:4650-8
3. Zawasdski JK, Dunaif A. Diagnostic criteria for polycystic ovary syndrome: towards a rational approach. In: Dunaif A, Givens JR, Haseltine FP, et al. eds. Polycystic Ovary Syndrome. Boston: Blackwell Scientific Publications, 1992:377-84
4. The Rotterdam ESHRE/ASRM-Sponsored PCOS consensus workshop group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod 2004;19:41-7
5. Broekmans FJ, Knauff EA, Valkenburg O, Laven JS, Eijkemans MJ, Fauser BC. PCOS according to the Rotterdam consensus criteria: change in prevalence among WHO-II anovulation and association with metabolic factors. BJOG 2006;113:1210-17
6. Chang WY, Knochenhauer ES, Bartolucci AA, Azziz R. Phenotypic spectrum of polycystic ovary syndrome: clinical and biochemical characterization of the three major clinical subgroups. Fertil Steril 2005;83:1717-23
7. Rosner W, Auchus RJ, Azziz R, Sluss PM, Raff H. Position statement: utility, limitations, and pitfalls in measuring testosterone: an Endocrine Society position statement. J Clin Endocrinol Metab 2007;92:405-13
8. Salameh WA, Goldman M, Caulfield MP, Clarke MJ, Azziz R, Reitz R. Optimal cutoffs for diagnosis of hyperandrogenemia in patients with the polycystic ovary syndrome (PCOS) by liquid chromatography tandem mass spectrometry (LC/MSMS) vs. extraction/chromatography radioimmunoassay (RIA). 5th Annual Meeting of the Androgen Excess Society, Toronto, Canada, 1 June 2007. Los Angeles: Androgen Excess Society
9. Kumar A, Woods KS, Bartolucci AA, Azziz R. Prevalence of adrenal androgen excess in patients with the polycystic ovary syndrome (PCOS). Clin Endocrinol 2005;62:644-9
10. Spencer J, Kumar A, Azziz R. The age-associated decline of androgens in reproductive age and menopausal black and white women. J Clin Endocrinol Metab 2007;92:4730-3
11. Azziz R, Sanchez LA, Knochenhauer ES, et al. Androgen excess in women: experience with over 1000 consecutive patients. J Clin Endocrinol Metab 2004;89:453-62
12. Carmina E, Rosato F, Janni A, Rizzo M, Longo RA. Extensive clinical experience: relative prevalence of different androgen excess disorders in 950 women referred because of clinical hyperandrogenism. J Clin Endocrinol Metab 2006;91:2-6
13. Vexiau P, Husson C, Chivot M, et al. Androgen excess in women with acne alone compared with women with acne and/or hirsutism. J Invest Dermatol 1990;94:279-83
14. Timpatanapong P, Rojanasakul A. Hormonal profiles and prevalence of polycystic ovary syndrome in women with acne. J Dermatol 1997;24:223-9
15. Borgia F, Cannavo S, Guarneri F, Cannavo SP, Vaccaro M, Guarneri B. Correlation between endocrinological parameters and acne severity in adult women. Acta Derm Venereol 2004;84:201-4
16. Futterweit W, Dunaif A, Yeh HC, Kingsley P. The prevalence of hyperandrogenism in 109 consecutive female patients with diffuse alopecia. J Am Acad Dermatol 1988;19:831-6
17. Cela E, Robertson C, Rush K, et al. Prevalence of polycystic ovaries in women with androgenic alopecia. Eur J Endocrinol 2003;149:439-42
18. Treloar AE, Boynton RE, Behn BG, Brown BW. Variation of the human menstrual cycle through reproductive life. Int J Fertil 1967;12:77-126
19. Legro RS, Myers ER, Barnhart HX, et al. The Pregnancy in Polycystic Ovary Syndrome Study: baseline characteristics of the randomized cohort including racial effects. Fertil Steril 2006;86:914-33
20. Adams J, Franks S, Polson DW, et al. Multifollicular ovaries: clinical and endocrine features and response to pulsatile gonadotropin releasing hormone. Lancet 1985;2:1375-9
21. Balen AH, Laven JS, Tan SL, Dewailly D. Ultrasound assessment of the polycystic ovary: international consensus definitions. Hum Reprod Update 2003;9:505-14
22. Jonard S, Robert Y, Dewailly D. Revisiting the ovarian volume as a diagnostic criterion for polycystic ovaries. Hum Reprod 2005;20:2893-8