Potent anti-prostate cancer agents derived from a novel androgen receptor down-regulating agent

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 7, 2008, Pages 3519-3529

  Purushottamachar, Puranik ^a   Khandelwal, Aakanksha ^a   Vasaitis, Tadas S ^a   Bruno, Robert D ^a   Gediya, Lalji K ^a   Njar, Vincent C O ^a,b  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

Author keywords

Anti prostate cancer agents; Antiproliferative; Structure activity relationship (SAR); Sulfonamides

Indexed keywords

(2 NITROPHENYL)(PHENYLSULFONYL)AMINE; (4 METHYL 2 NITROPHENYL)(PHENYLSULFONYL)AMINE; (4 METHYLPHENY)[(4 METHYLPHENYL)SULFONYL]AMINE; (4 METHYLPHENYL)(PHENYLSULFONYL)AMINE; (4 METHYLPHENYL)[(METHYLPHENYL)METHYL]AMINE; 1 AZA 1,2 BIS(4 METHYLPHENYL)ETHANE; 2 (1H 1,2,3,4 TETRAZOLE 5 YL) 5 METHYLPHENYL)[(4 FLUOROPHENYL)SULFONYL]AMINE; 2 [[(4 FLUOROPHENYL)SULFONYL]AMINO] 4 METHYLBENZENECARBONITRILE; 5 METHYL 2 [(PHENYLSULFONYL)AMINO]BENZOIC ACID; [(4 FLUROPHENYL)SULFONYL](4 METHYL 2 NITROPHENYL)AMINE; [(4 METHYLPHENYL)SULFONYL](2 NITROPHENYL)AMINE; [(4 METHYLPHENYLSULFONYL]PHENYLAMINE; [[(4 FLUOROPHENYL)SULFONYL]AMINO] 5 METHYLBENZOIC ACID; ALPHA TOCOPHEROL SUCCINATE; ANTINEOPLASTIC AGENT; CURCUMIN; EPICATECHIN; FLUFENAMIC ACID; METHYL(4 METHYLPHENYL)[(4 METHYLPHENYL)SULFONYL]AMINE; PHENYL(PHENYLSULFONYL)AMINE; QUERCETIN; SELECTIVE ANDROGEN RECEPTOR MODULATOR; SULFONAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CELL GROWTH; CELL VIABILITY; DOWN REGULATION; DRUG ACTIVITY; DRUG POTENCY; HORMONE SENSITIVITY; HUMAN; HUMAN CELL; PROSTATE CANCER; PROTEIN EXPRESSION; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

AMINES; ANDROGENS; ANTINEOPLASTIC AGENTS, HORMONAL; CELL LINE, TUMOR; CELL SURVIVAL; DOWN-REGULATION; HUMANS; IMINES; MALE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROSTATIC NEOPLASMS; RECEPTORS, ANDROGEN; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION, GENETIC;

EID: 41649093949     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.02.031     Document Type: Article

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