Novel splice isoforms of STRADα differentially affect LKB1 activity, complex assembly and subcellular localization

Cancer Biology and Therapy

Volumn 6, Issue 10, 2007, Pages 1627-1631

  Marignani, P A ^a   Scott, K D ^a   Bagnulo, R ^b   Cannone, D ^b   Ferrari, E ^b,c   Stella, A ^b   Guanti, G ^b   Simone, C ^b,d   Resta, N ^b  

^a DALHOUSIE UNIVERSITY   (Canada)

^b UNIVERSITY OF BARI   (Italy)

^c UNIVERSITY OF SIENA   (Italy)

^d Temple University   (United States)

Author keywords

Colorectal cancer; LKB1; MO25; Peutz Jeghers syndrome; STRAD

Indexed keywords

ADENYLATE KINASE; COMPLEMENTARY DNA; CYCLIN D1; ISOPROTEIN; PROTEIN KINASE; PROTEIN KINASE LKB1; PROTEIN KINASE STRADALPHA; PROTEIN MO25; PROTEIN SERINE THREONINE KINASE; SCAFFOLD PROTEIN; STK11 PROTEIN, HUMAN; STRAD PROTEIN, HUMAN; UNCLASSIFIED DRUG; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ARTICLE; CELL DIFFERENTIATION; CELL METABOLISM; CELL POLARITY; CELL PROLIFERATION; CHEEK MUCOSA; COLORECTAL CANCER; COMPLEX FORMATION; DRUG DESIGN; DRUG TARGETING; GENE MUTATION; GENETIC PREDISPOSITION; HAMARTOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERPIGMENTATION; INTESTINE CELL; INTESTINE EPITHELIUM CELL; NUCLEOTIDE SEQUENCE; PEUTZ JEGHERS SYNDROME; PROMOTER REGION; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE; ALTERNATIVE RNA SPLICING; COLORECTAL TUMOR; CYTOLOGY; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; TUMOR CELL LINE;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ALTERNATIVE SPLICING; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL POLARITY; COLORECTAL NEOPLASMS; ENTEROCYTES; HUMANS; PROTEIN ISOFORMS; PROTEIN-SERINE-THREONINE KINASES; TRANSCRIPTION, GENETIC;

EID: 41649089845     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.6.10.4787     Document Type: Article

References (27)