Senile systemic amyloidosis affects 25% of the very aged and associates with genetic variation in alpha2-macroglobulin and tau: A population-based autopsy study

Annals of Medicine

Volumn 40, Issue 3, 2008, Pages 232-239

  Tanskanen, Maarit ^a   Peuralinna, Terhi ^b   Polvikoski, Tuomo ^c   Notkola, Irma Leena ^d   Sulkava, Raimo ^e   Hardy, John ^f   Singleton, Andrew ^f   Kiuru Enari, Sari ^a,b   Paetau, Anders ^a   Tienari, Pentti J ^a,b   Myllykangas, Liisa ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b Neurosciences Programme   (Finland)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

^d Finnish Information Centre for Register Research   (Finland)

^e UNIVERSITY OF EASTERN FINLAND   (Finland)

^f NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

Age; Alpha2 macroglobulin; Autopsy; Gene; Myocardial infarction; Senile systemic amyloidosis; Tau; Transthyretin

Indexed keywords

CONGO RED; PREALBUMIN; VALINE;

AGED; ALPHA2 MACROGLOBULIN GENE; AMYLOIDOSIS; ARTICLE; AUTOPSY; DISEASE ASSOCIATION; EXON; FEMALE; FINLAND; GENE; GENE FREQUENCY; GENETIC RISK; GENETIC VARIABILITY; HAPLOTYPE; HEART INFARCTION; HEART MUSCLE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; POPULATION RESEARCH; PREVALENCE; PRIORITY JOURNAL; RISK FACTOR; SENILE AMYLOIDOSIS; TAU GENE;

AGE FACTORS; AGED, 80 AND OVER; ALPHA-MACROGLOBULINS; AMYLOIDOSIS; AUTOPSY; CONGO RED; EXONS; FEMALE; FINLAND; GENE FREQUENCY; HAPLOTYPES; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MYOCARDIAL INFARCTION; MYOCARDIUM; POLYMORPHISM, GENETIC; PREALBUMIN; PREVALENCE; RISK FACTORS; TAU PROTEINS;

EID: 41649088603     PISSN: 07853890     EISSN: 16512219     Source Type: Journal    
DOI: 10.1080/07853890701842988     Document Type: Article

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