Effect of aminoguanidine on post-ischemic damage in rodent model of stroke

Pakistan Journal of Pharmaceutical Sciences

Volumn 21, Issue 1, 2008, Pages 24-28

  Vakili, Abedin ^a   Zahedi Khorasani, Mahdi ^a  

^a SEMNAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Acute phase; Aminoguanidine; Neurological dysfunction; Transient focal cerebral ischemic

Indexed keywords

AMINOGUANIDINE; SODIUM CHLORIDE; GUANIDINE DERIVATIVE; NEUROPROTECTIVE AGENT; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION SIZE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOTOR DYSFUNCTION; NONHUMAN; RAT; REPERFUSION INJURY; STROKE; TRANSIENT ISCHEMIC ATTACK; ANALYSIS OF VARIANCE; ANIMAL; CEREBRAL ARTERY DISEASE; DISEASE MODEL; DRUG ADMINISTRATION; DRUG ANTAGONISM; METABOLISM; MOTOR ACTIVITY; PATHOLOGY; PATHOPHYSIOLOGY; WISTAR RAT;

ANALYSIS OF VARIANCE; ANIMALS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; GUANIDINES; INFARCTION, MIDDLE CEREBRAL ARTERY; ISCHEMIC ATTACK, TRANSIENT; MALE; MOTOR ACTIVITY; NEUROPROTECTIVE AGENTS; NITRIC OXIDE SYNTHASE; RATS; RATS, WISTAR; REPERFUSION INJURY; STROKE;

EID: 41649086833     PISSN: 1011601X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Barone FC, Arvin B, White RF, Miller A, Webb CL, Willette RN and Lysko PG (1997). Feuerstein GZ. Tumor necrosis factor-alpha a mediator of focal ischemic brain injury. Stroke, 28: 1233-1244. (Pubitemid 27248902)
2. Brownlee M, Vlassara H, Kooney A, Ulrich P and Cerami A (1986). Aminoguanidine prevents diabetes-induced arterial wall protein cross-linking. Science, 232: 1629-1632. (Pubitemid 16095602)
3. Cash D, Beech JS, Rayne RC, Bath PM, Meldrum BS and Williams SC (2001). Neuroprotective effect of aminoguanidine on transient focal ischaemia in the rat brain. Brain Res., 29: 91-103. (Pubitemid 32553842)
4. Chan PH (1994). Oxygen radical in focal cerebral ischemia. Brain Pathol., 4: 59-65. (Pubitemid 24077892)
5. Cockroft KM, Meistrell M, Zimmerman GA, Risucci D, Bloom O, Cerami A, Tracey KJ (1996). Cerebro-protective effects of aminoguanidine in a rodent model of stroke. Stroke, 27: 1393-1398. (Pubitemid 26286174)
6. Danielisova V, Nemethova M and Burda J (2004). The protective effect of aminoguanidine on cerebral ischemic damage in the rat brain. Physiol Res., 53: 533-540 (Pubitemid 39486711)
7. Giardino I., Fard AK, Hatchell DL and Brownlee M (1998). Aminoguanidine inhibits reactive oxygen species formation, lipid peroxidation,and oxidant-induced apoptosis. Diabetes, 47: 1114-1120. (Pubitemid 28294555)
8. Huang Z, Huang PL, Ma J, Meng W, Ayata C, Fishman MC and Moskowitz MA (1996). Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine. J. Cereb. Blood Flow Metab., 16: 981-987. (Pubitemid 26292066)
9. Iadecola C, Zhang F, Xu X, Casey R and Ross ME (1995b). Inducible nitric oxide synthase gene expression in brain following focal cerebral ischemia. J. Cereb. Blood Flow Metab., 15: 378-384.
10. Iadecola C, Zhang F and Xu X (1995a). Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage. Am. J. Physiol., 268: R286-R292.
11. Kondo T, Reaume AG, Huang TT, Carlson E, Murakami K, Chen SF, Hoffman EK, Scott RW, Epstein CJ and Chan PH (1997). Reduction of CuZn-superoxide dismutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia. J. Neurosci., 17: 4180-4189 (Pubitemid 27220609)
12. Laszlo F, Evans SM and Whittle BJR (1995). Amino-guanidine inhibits both constitutive and inducible nitric oxide synthase isoforms in rat intestinal micro-vasculature in vivo. Eur. J. Pharmacol., 272: 169-175.
13. Nagayama M, Zhang F and Iadecola C (1998). Delayed treatment with aminoguanidine decreases focal cerebral ischemic damage and enhances neurologic recovery in rats. J. Cerebral Blood Flow Metab., 18: 1107-1113. (Pubitemid 28465358)
14. Nelson CW, Wei EP, Povlishock JT, Kontos HA and Moskowitz MA (1992). Oxygen radicals in cerebral ischemia. Am. J. Physiol., 263: H1356-H13562.
15. Plesnila N, Zhu C, Culmsee C, Groger M, Moskowitz MA and Blomgren K (2004). Nuclear translocation of apoptosisinducing factor after focal cerebral ischemia. J. Cereb. Blood Flow Metab., 24: 458-466. (Pubitemid 38452237)
16. Sugimoto K and Iadecola C (2002). Effects of aminoguanidine on cerebral ischemia in mice: comparison between mice with and without inducible nitric oxide synthase gene. Neurosci. Lett., 331: 25-28.
17. Swanson RA, Morton MT, Tsao-Wu G, Savalos RA, Davidson C, Sharp FR (1990). Semiautomated method for measuring brain infarct volume. J. Cerebral Blood Flow Metab., 10: 290-293. (Pubitemid 20096202)
18. Takizawa S, Fukuyama N, Hirabayashi H, Nakazawa H, Shinohara Y (1999). Dynamics of nitrotyrosine formation and decay in rat brain during focal ischemiareperfusion. J. Cereb Blood Flow Metab., 19: 667-672. (Pubitemid 30161219)
19. Vakili A, Kataoka H, Plesnila N (2005). Role of arginine vasopressin V1 and V2 receptors for brain damage after transient focal cerebral ischemia. J. Cerebral Blood Flow Metab., 25: 1012-1019. (Pubitemid 41061716)
20. Vakili A, Nekoeian AA, Dehghani GA (2006). Aminoguanidine reduces infarct volume and improve neurological dysfunction in rat model focal cerebral ischemia. DARU, 14: 31-36. (Pubitemid 43971931)
21. Vakili A and Zahedi Khorasani M (2007). Post-ischemic treatment of pentoxifyline reduces cortical not striatal infarct volume in transient model of focal cerebral ischemia in rat. Brain Res., 1144: 186-191. (Pubitemid 46440843)
22. Yildiz G, Demiryurek AT, Sahin-Erdemli I., Kanzik I (1998). Comparison of antioxidant activities of aminoguanidine, methylguanidine and guanidine by luminol-enhanced chemiluminescence. Br. J. Pharmacol., 124: 905-910 (Pubitemid 28312824)
23. Zhang F and Iadecola C (1998). Temporal characteristics of the protective effect of aminoguanidine on cerebral ischemic damage. Brain Res., 802: 104-110. (Pubitemid 28392161)
24. Zhang F, Robyn M, Casey BS, Ross ME and Iadecola C (1996). Aminoguanidine ameliorates and L-arginine worsens brain damage from intraluminal middle cerebral artery occlusion. Stroke, 27: 317-323. (Pubitemid 26044507)
25. Zhang XM and Ellis EF (1990). Superoxide dismutase reduces permeability and edema induced by hypertension in rats. Am. J. Physiol., 259, H497-H503.
26. Zimmerman GA, Meistrell MI, Bloom O, Cockroft KM, Bianchi M, Risucci D, Broome J, Farmer P, Cerami A, Vlassara H and Tracey KJ (1995). Neurotoxicity of advanced glycation endproducts during focal stroke and neuroprotective effects of aminoguanidine. Proc. Natl. Acad. Sci., USA. 92: 3744-13374