Staphylococcus aureus pathogenicity island DNA is packaged in particles composed of phage proteins

Journal of Bacteriology

Volumn 190, Issue 7, 2008, Pages 2434-2440

  Tormo, María Ángeles ^a,b   Ferrer, María Desamparados ^a,b   Maiques, Elisa ^a,b   Úbeda, Carles ^c   Selva, Laura ^a,b   Lasa, Íñigo ^d   Calvete, Juan J ^e   Novick, Richard P ^c   Penadés, José R ^a,b,f  

^a INSTITUTO VALENCIANO DE INVESTIGACIONES AGRARIAS IVIA   (Spain)

^b UNIVERSIDAD CEU CARDENAL HERRERA   (Spain)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d CSIC   (Spain)

^e INSTITUTO DE BIOMEDICINA DE VALENCIA   (Spain)

^f Centro de Investigación Y Tecnología Animal   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIOPHAGE DNA; CAPSID PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BACTERIAL GROWTH; BACTERIOPHAGE; MASS SPECTROMETRY; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENICITY ISLAND; PRIORITY JOURNAL; PROTEIN ANALYSIS; STAPHYLOCOCCUS AUREUS;

DNA, BACTERIAL; GENETIC COMPLEMENTATION TEST; GENOMIC ISLANDS; MICROSCOPY, ELECTRON; MUTATION; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS PHAGES; TANDEM MASS SPECTROMETRY; VIRAL PROTEINS;

MIRIDAE; STAPHYLOCOCCUS AUREUS;

EID: 41549143962     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.01349-07     Document Type: Article

References (22)

1. Agarwal, M., M. Arthur, R. D. Arbeit, and R. Goldstein. 1990. Regulation of icosahedral virion capsid size by the in vivo activity of a cloned gene product. Proc. Natl. Acad. Sci. USA 87:2428-2432.
2. Arnaud, M., A. Chastanet, and M. Debarbouille. 2004. New vector for efficient allelic replacement in naturally nontransformable, low-GC-content, gram-positive bacteria. Appl. Environ. Microbiol. 70:6887-6891.
3. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl. 1990. Current protocols in molecular biology. John Wiley & Sons, New York, NY.
4. Charpentier, E., A. I. Anton, P. Barry, B. Alfonso, Y. Fang, and R. P. Novick. 2004. Novel cassette-based shuttle vector system for gram-positive bacteria. Appl. Environ. Microbiol. 70:6076-6085.
5. Heller, K. J. 1984. Identification of the phage gene for host receptor specificity by analyzing hybrid phages of T5 and BF23. Virology 139:11-21.
6. Kreiswirth, B. N., S. Lofdahl, M. J. Betley, M. O'Reilly, P. M. Schlievert, M. S. Bergdoll, and R. P. Novick. 1983. The toxic shock syndrome exotoxin structural gene is not detectably transmitted by a prophage. Nature 305:709-712.
7. Kwan, T., J. Liu, M. Dubow, P. Gros, and J. Pelletier. 2005. The complete genomes and proteomes of 27 Staphylococcus aureus bacteriophages. Proc. Natl. Acad. Sci. USA 102:5174-5179.
8. Lindsay, J. A., A. Ruzin, H. F. Ross, N. Kurepina, and R. P. Novick. 1998. The gene for toxic shock toxin is carried by a family of mobile pathogenicity islands in Staphylococcus aureus. Mol. Microbiol. 29:527-543.
9. Maiques, E., C. Ubeda, S. Campoy, N. Salvador, I. Lasa, R. P. Novick, J. Barbe, and J. R. Penades. 2006. β-Lactam antibiotics induce the SOS response and horizontal transfer of virulence factors in Staphylococcus aureus. J. Bacteriol. 188:2726-2729.
10. Maiques, E., C. Ubeda, M. A. Tormo, M. D. Ferrer, I. Lasa, R. P. Novick, and J. R. Penades. 2007. Role of staphylococcal phage and SaPI integrase in intra- and interspecies SaPI transfer. J. Bacteriol. 189:5608-5616.
11. Novick, R. 1967. Properties of a cryptic high-frequency transducing phage in Staphylococcus aureus. Virology 33:155-166.
12. Novick, R. P. 1991. Genetic systems in staphylococci. Methods Enzymol. 204:587-636.
13. Novick, R. P., and A. Subedi. 2007. The SaPIs: mobile pathogenicity islands of Staphylococcus. Chem. Immunol. Allergy 93:42-57.
14. Ruzin, A., J. Lindsay, and R. P. Novick. 2001. Molecular genetics of SaPI1 - a mobile pathogenicity island in Staphylococcus aureus. Mol. Microbiol. 41:365-377.
15. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
16. Tallent, S. M., T. B. Langston, R. G. Moran, and G. E. Christie. 2007. Transducing particles of Staphylococcus aureus pathogenicity island SaPI1 are comprised of helper phage-encoded proteins. J. Bacteriol. 189:7520-7524.
17. Ubeda, C., P. Barry, J. R. Penades, and R. P. Novick. 2007. A pathogenicity island replicon in Staphylococcus aureus replicates as an unstable plasmid. Proc. Natl. Acad. Sci. USA 104:14182-14188.
18. Ubeda, C., E. Maiques, P. Barry, A. Matthews, M. A. Tormo, I. Lasa, R. P. Novick, and J. R. Penades. 2008. SaPI mutations affecting replication and transfer and enabling autonomous replication in the absence of helper phage. Mol. Microbiol. 67:493-503.
19. Ubeda, C., E. Maiques, E. Knecht, I. Lasa, R. P. Novick, and J. R. Penades. 2005. Antibiotic-induced SOS response promotes horizontal dissemination of pathogenicity island-encoded virulence factors in staphylococci. Mol. Microbiol. 56:836-844.
20. Ubeda, C., E. Maiques, M. A. Tormo, S. Campoy, I. Lasa, J. Barbe, R. P. Novick, and J. R. Penades. 2007. SaPI operon I is required for SaPI packaging and is controlled by LexA. Mol. Microbiol. 65:41-50.
21. Ubeda, C., M. A. Tormo, C. Cucarella, P. Trotonda, T. J. Foster, I. Lasa, and J. R. Penades. 2003. Sip, an integrase protein with excision, circularization and integration activities, defines a new family of mobile Staphylococcus aureus pathogenicity islands. Mol. Microbiol. 49:193-210.
22. Wang, J., M. Hofnung, and A. Charbit. 2000. The C-terminal portion of the tail fiber protein of bacteriophage lambda is responsible for binding to LamB, its receptor at the surface of Escherichia coli K-12. J. Bacteriol. 182:508-512.