Comparison of weight gain in treatments for tourette syndrome: Tetrabenazine versus neuroleptic drugs

Journal of Child Neurology

Volumn 23, Issue 4, 2008, Pages 435-437

  Ondo, William G ^a   Jong, Daniel ^a   Davis, Anthony ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Neuroleptics; Tetrabenazine; Tics; Tourette syndrome; Weight

Indexed keywords

ARIPIPRAZOLE; FLUPHENAZINE; HALOPERIDOL; NEUROLEPTIC AGENT; RISPERIDONE; TETRABENAZINE;

ADOLESCENT; AGE; AKATHISIA; ANXIETY; ARTICLE; BODY WEIGHT; CHILD; COGNITION; CONTROLLED STUDY; DEPRESSION; DRUG EFFICACY; DRUG SUBSTITUTION; DRUG WITHDRAWAL; DYSTONIA; FATIGUE; FEMALE; GILLES DE LA TOURETTE SYNDROME; HUMAN; INSOMNIA; MAJOR CLINICAL STUDY; MALE; NAUSEA; PATIENT MONITORING; PRIORITY JOURNAL; SIDE EFFECT; SOMNOLENCE; TIC; WEIGHT GAIN; WEIGHT REDUCTION;

ADOLESCENT; ADRENERGIC UPTAKE INHIBITORS; ANTIPSYCHOTIC AGENTS; CHILD; FEMALE; HUMANS; MALE; TETRABENAZINE; TOURETTE SYNDROME; WEIGHT GAIN;

EID: 41549139651     PISSN: 08830738     EISSN: None     Source Type: Journal    
DOI: 10.1177/0883073807307108     Document Type: Article

References (11)

1. Definitions and classification of tic disorders. The Tourette Syndrome Classification Study Group. Arch Neurol. 1993;50:1013-1016.
2. Jankovic J. Tourettes syndrome. N Engl J Med. 2001;345:1184-1192.
3. Allison DB, Mentore JL, Heo M., Chandler LP, et al. Antipsychotic-induced weight gain: A comprehensive research synthesis. Am J Psychiatry. 1999;156:1686-1696.
4. Takimoto GS, Stittsworth JD Jr, Bianchi BR, Stephens JK Differential sensitivity of hypothalamic norepinephrine and striatal dopamine to catecholamine-depleting agents. J Pharmacol Exp Ther. 1983;226:432-439.
5. Scahill L., Leckman JF, Schultz RT, Katsovich L., Peterson BS A placebo-controlled trial of risperidone in Tourette syndrome. Neurology. 2003;60:1130-1135.
6. Matsui- Sakata A., Ohtani H., Sawada Y. Receptor occupancy-based analysis of the contributions of various receptors to antipsychotics-induced weight gain and diabetes mellitus. Drug Metab Pharmacokinet. 2005;20:368-378.
7. Kenney C., Jankovic J. Tetrabenazine in the treatment of hyperkinetic movement disorders. Expert Rev Neurother. 2006;6:7-17.
8. Paleacu D., Giladi N., Moore O., Stern A., Honigman S., Badarny S. Tetrabenazine treatment in movement disorders. Clin Neuropharmacol. 2004;27:230-233.
9. Hunter C., Jankovic J. Long-term tolerability of tetrabenazine in the treatment of hyperkinetic movement disorders. Mov Disord. 2007;22:193-197.
10. Huntington Study Group. Tetrabenazine as antichorea therapy in Huntington disease: A randomized controlled trial. Neurology. 2006;66:366-372.
11. Kenney C., Hunter C., Mejia, N., Jankovic J. Tetrabenazine in the treatment of Tourette syndrome. J Pediatr Neurol. 2007;5:11-16.