Age-related decline in rate of torque development is accompanied by lower maximal motor unit discharge frequency during fast contractions

Journal of Applied Physiology

Volumn 104, Issue 3, 2008, Pages 739-746

  Klass, Malgorzata ^a   Baudry, Stéphane ^a   Duchateau, Jacques ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

Doublet discharge; Electromyogram; Muscle twitch; Skeletal muscle

Indexed keywords

ADULT; AGED; AGING; ANKLE; ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; ELECTROMYOGRAPHY; ELECTROSTIMULATION; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; MOTOR UNIT; MUSCLE CONTRACTION; MUSCLE ISOMETRIC CONTRACTION; MUSCLE TWITCH; NORMAL HUMAN; PRIORITY JOURNAL; RECORDING; SKELETAL MUSCLE; TIBIALIS ANTERIOR MUSCLE; TORQUE; VOLUNTARY MOVEMENT;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; AGING; ANKLE; ELECTROMYOGRAPHY; EXERCISE; FEMALE; HUMANS; ISOMETRIC CONTRACTION; MALE; MOTOR NEURONS; MUSCLE, SKELETAL; TIME FACTORS; TORQUE;

EID: 41549136871     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00550.2007     Document Type: Article

References (44)

1. Andersen LL, Aagaard P. Influence of maximal muscle strength and intrinsic muscle contractile properties on contractile rate of force development. Eur J Appl Physiol 96: 46-52, 2006.
2. Baldissera F, Campadelli P, Piccinelli L. The dynamic response of cat gastrocnemius motor units investigated by ramp-current injection into their motoneurones. J Physiol 387: 317-330, 1987.
3. Barry BK, Pascoe MA, Jesunathadas M, Enoka RM. Rate coding is compressed but variability is unaltered for motor units in a hand muscle of old adults. J Neurophysiol 97: 3206-3218, 2007.
4. Barry BK, Warman GE, Carson RG. Age-related differences in rapid muscle activation after rate of force development training of the elbow flexors. Exp Brain Res 162: 122-132, 2005.
5. Baudry S, Klass M, Duchateau J. Postactivation potentiation influences differently the nonlinear summation of contractions in young and elderly adults. J Appl Physiol 98: 1243-1250, 2005.
6. Bawa P, Calancie B. Repetitive doublets in human flexor carpi radialis muscle. J Physiol 339: 123-132, 1983.
7. Bigland-Ritchie BR, Dawson NJ, Johansson RS, Lippold OC. Reflex origin for the slowing of motoneurone firing rates in fatigue of human voluntary contractions. J Physiol 379: 451-459, 1986.
8. Binder MD, Heckman CJ, Powers RK. The physiological control of motoneuron activity. In: Handbook of Physiology. Exercise: Regulation and Integration of Multiple Systems. Bethesda, MD: Am. Physiol. Soc., 1996, sect. 12, vol. I, chapt. 1, p. 3-53.
9. Calvin WH, Schwindt PC. Steps in production of motoneuron spikes during rhythmic firing. J Neurophysiol 35: 297-310, 1972.
10. Chalmers GR, Knutzen KM. Recurrent inhibition in the soleus motor pool of elderly and young adults. Electromyogr Clin Neurophysiol 44: 413-421, 2004.
11. Christie A, Kamen G. Doublet discharges in motoneurons of young and older adults. J Neurophysiol 95: 2787-2795, 2006.
12. Connelly DM, Rice CL, Roos MR, Vandervoort AA. Motor unit firing rate and contractile properties in tibialis anterior of young and old men. J Appl Physiol 87: 843-852, 1999.
13. D'Antona G, Pellegrino MA, Adami R, Rossi R, Carlizzi CN, Canepari M, Saltin B, Bottinelli R. The effect of ageing and immobilization on structure and function of human skeletal muscle fibres. J Physiol 552: 499-511, 2003.
14. Desmedt JE, Godaux E. Ballistic contractions in man: characteristic recruitment pattern of single motor units of the tibialis anterior muscle. J Physiol 264: 673-693, 1977.
15. Desmedt JE, Godaux E. Ballistic contractions in fast and slow human muscles: discharge patterns of single motor units. J Physiol 285: 185-196, 1978.
16. Eisen A, Siejka S, Schulzer M, Calne D. Age-dependent decline in motor evoked potential (MEP) amplitude: with a comment on changes in Parkinson's disease. Electroencephalogr Clin Neurophysiol 81: 209-215, 1991.
17. Englehardt JK, Morales FR, Yamuy J, Chase MH. Cable properties of spinal motoneurons in adults and aged cats. J Neurophysiol 61: 194-201, 1989.
18. Gardiner PF. Changes in -motoneuron properties with altered physical activity levels. Exerc Sport Sci Rev 34: 54-58, 2006.
19. Garland SJ, Griffin L. Motor unit double discharges: statistical anomaly or functional entity? Can J Appl Physiol 24: 113-130, 1999.
20. Granit R, Kernell D, Shortess GK. Quantitative aspects of repetitive firing of mammalian motoneurones, caused by injected currents. J Physiol 168: 911-931, 1963.
21. Izquierdo M, Aguado X, Gonzalez R, López JL, Häkkinen K. Maximal and explosive force production capacity and balance performance in men of different ages. Eur J Appl Physiol 9: 260-267, 1999.
22. Kamen G, Knight CA. Training-related adaptations in motor units discharge rate in young and older adults. J Gerontol A Biol Sci Med Sci 59: 1334-1338, 2004.
23. Kamen G, Sison SV, Du CC, Patten C. Motor unit discharge behavior in older adults during maximal-effort contractions. J Appl Physiol 79: 1908-1913, 1995.
24. Keenan KG, Farina D, Maluf KS, Merletti R, Enoka RM. Influence of amplitude cancellation on the simulated surface electromyogram. J Appl Physiol 98: 120-131, 2005.
25. Kent-Braun JA, Ng AV. Specific strength and voluntary muscle activation in young and elderly women and men. J Appl Physiol 87: 22-29, 1999.
26. Klass M, Baudry S, Duchateau J. Aging does not affect voluntary activation of the ankle dorsiflexors during isometric, concentric, and eccentric contractions. J Appl Physiol 99: 31-38, 2005.
27. Klein CS, Rice CL, Marsh GD. Normalized force, activation, and coactivation in the arm muscles of young and old men. J Appl Physiol 91: 1341-1349, 2001.
28. Lexell J. Ageing and human muscle: observations from Sweden. Can J Appl Physiol 18: 2-18, 1993.
29. Masakado Y, Noda Y, Nagata MA, Kimura A, Chino N, Akaboshi K. Macro-EMG and motor unit recruitment threshold: differences between the young and the aged. Neurosci Lett 179: 1-4, 1994.
30. McNeil CJ, Doherty TJ, Stashuk DW, Rice CL. Motor unit number estimates in the tibialis anterior muscle of young, old, and very old men. Muscle Nerve 31: 461-467, 2005.
31. Morales FR, Boxer PA, Fung SJ, Chase MH. Basic electrophysiological properties of spinal cord motoneurons during old age in the cat. J Neurophysiol 58: 180-194, 1987.
32. Moritz CT, Barry BK, Pascoe MA, Enoka RM. Discharge rate variability influences the variation in force fluctuations across the working range of a hand muscle. J Neurophysiol 93: 2449-2459, 2005.
33. Mottram CJ, Jakobi JM, Semmler JG, Enoka RM. Motor-unit activity differs with load type during a fatiguing contraction. J Neurophysiol 93: 1381-1392, 2005.
34. Narici MV, Maganaris CN. Adaptability of elderly human muscles and tendons to increased loading. J Anat 208: 433-443, 2006.
35. Ng AV, Kent-Braun JA. Slowed muscle contractile properties are not associated with a decreased EMG/force relationship in older humans. J Gerontol A Biol Sci Med Sci 54: B452-B458, 1999.
36. Piotrkiewicz M, Kudina L, Mierzejewska J, Jakubiec M, Hausmanowa-Petrusewicz I. Age-related change in duration of afterhyperpolarization of human motoneurones. J Physiol 585: 483-590, 2007.
37. Pitcher JB, Ogston KM, Miles TS. Age and sex differences in human motor cortex input-output characteristics. J Physiol 546: 605-613, 2003.
38. Roos MR, Rice CL, Connelly DM, Vandervoort AA. Quadriceps muscle strength, contractile properties, and motor units firing rates in young and old men. Muscle Nerve 22: 1094-1103, 1999.
39. Roos MR, Rice CL, Vandervoort AA. Age-related changes in motor unit function. Muscle Nerve 20: 679-690, 1997.
40. Sale MV, Semmler JG. Age-related differences in corticospinal control during functional isometric contractions in left and right hands. J Appl Physiol 99: 1483-1493, 2005.
41. Simoneau E, Martin A, Van Hoecke J. Muscular performances at the ankle joint in young and elderly men. J Gerontol A Biol Sci Med Sci 60: 439-447, 2005.
42. Smith L, Zhong T, Bawa P. Nonlinear behaviour of human motoneurons. Can J Physiol Pharmacol 73: 113-123, 1995.
43. Van Cutsem M, Duchateau J. Preceding muscle activity influences motor unit discharge and rate of torque development during ballistic contractions in humans. J Physiol 562: 635-644, 2005.
44. Van Cutsem M, Duchateau J, Hainaut K. Changes in single motor units behaviour contribute to the increase in contraction speed after dynamic training in humans. J Physiol 513: 295-305, 1998.