"Intention to analyze" in pharmacogenomics studies

Cancer Epidemiology Biomarkers and Prevention

Volumn 17, Issue 3, 2008, Pages 740-

  Gwinn, Marta ^a   Guessous, Idris ^b   Khoury, Muin J ^a  

^a NATIONAL CENTER ON BIRTH DEFECTS AND DEVELOPMENTAL DISABILITIES   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOL METHYLTRANSFERASE; NICOTINE PATCH;

DNA POLYMORPHISM; GENOTYPE; LETTER; MEDICAL RESEARCH; PHARMACOGENOMICS; PRIORITY JOURNAL; SMOKING CESSATION;

EID: 41549125997     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-07-2929     Document Type: Letter

References (11)

1. 108/158Met genotype with smoking cessation in a nicotine replacement therapy randomized trial. Cancer Epidemiol Biomarkers Prev 2007;16:1065-9.
2. Imperial Cancer Research Fund. Effectiveness of a nicotine patch in helping people stop smoking: results of a randomized trial in general practice. Br Med J 1993;306:1304-8.
3. Johnstone EC, Yudkin PL, Hey K, et al. Genetic variation in dopaminergic pathways and short-term effectiveness of the nicotine patch. Pharmacogenetics 2004;14:83-90.
4. Munafo MR, Johnstone EC, Wileyto EP, Shields PG, Elliot KM, Lerman C. Lack of association of 5-HTTLPR genotype with smoking cessation in a nicotine replacement therapy randomized trial. Cancer Epidemiol Biomarkers Prev 2006;15:398-400.
5. David SP, Munafo MR, Murphy MF, Proctor M, Walton RT, Johnstone EC. Genetic variation in the dopamine D4 receptor (DRD4) gene and smoking cessation: follow-up of a randomised clinical trial of transdermal nicotine patch. Pharmacogenomics J 2007;27:1-7.
6. David SP, Munafo MR, Murphy MF, Walton RT, Johnstone EC. The serotonin transporter 5-HTTLPR polymorphism and treatment response to nicotine patch: follow-up of a randomized controlled trial. Nicotine Tob Res 2007;9:225-31.
7. Munafo MR, Elliot KM, Murphy MF, Walton RT, Johnstone EC. Association of the μ-opioid receptor gene with smoking cessation. Pharmacogenomics J 2007;16:1-9.
8. Hollis S, Campbell F. What is meant by intention to treat analysis? Survey of published randomised controlled trials. BMJ 1999;319:670-4.
9. Khoury MJ, Little J, Gwinn M, Ioannidis JP. On the synthesis and interpretation of consistent but weak gene-disease associations in the era of genome-wide association studies. Int J Epidemiol 2007;36:439-45.
10. NCI-NHGRI Working Group on Replication in Association Studies; Chanock SJ, Manolio T, et al. Replicating genotype-phenotype associations. Nature 2007;447:655-60.
11. Ioannidis JP, Gwinn M, Little J, et al. A road map for efficient and reliable human genome epidemiology. Nat Genet 2006;38:3-5.