메뉴 건너뛰기




Volumn 12, Issue 2, 2008, Pages 205-217

A semantic grid infrastructure enabling integrated access and analysis of multilevel biomedical data in support of postgenomic clinical trials on cancer

Author keywords

Biomedical grid; Biomedical Grid; Cancer; Metadata; Ontology; Post genomic clinical trials; Postgenomic clinical trials; Semantic integration of heterogeneous biomedical databases

Indexed keywords

COMPUTATIONAL METHODS; GRID COMPUTING; MEDICAL COMPUTING; METADATA; ONCOLOGY; SEMANTICS;

EID: 41549120240     PISSN: 10897771     EISSN: None     Source Type: Journal    
DOI: 10.1109/TITB.2007.903519     Document Type: Article
Times cited : (43)

References (43)
  • 1
    • 67549101818 scopus 로고    scopus 로고
    • Accelerating cancer research
    • Jun. 21, Online, Available
    • K. Yurkewicz. (2006, Jun. 21). Accelerating cancer research. Sci. Grid. [Online]. Available: http://www.interactions.org/sgtw/2006/ 0621/cabig_more.html
    • (2006) Sci. Grid
    • Yurkewicz, K.1
  • 2
    • 18244382546 scopus 로고    scopus 로고
    • Cyberinfrastructure: Empowering a "third way" in biomedical research
    • K. H. Buetow, "Cyberinfrastructure: Empowering a "third way" in biomedical research," Sci. Mag., vol. 308, no. 5723, pp. 821-824, 2005.
    • (2005) Sci. Mag , vol.308 , Issue.5723 , pp. 821-824
    • Buetow, K.H.1
  • 3
    • 33750935647 scopus 로고    scopus 로고
    • Developing European biomedical grid on cancer: The ACGT integrated project
    • Valencia, Spain, Stud Health Technol. Inf, Jun. 6-8
    • M. Tsiknakis, D. Kafetzopoulos, G. Potamias, C. Marias, A. Analyti, and A. Manganas, "Developing European biomedical grid on cancer: The ACGT integrated project," in Proc. HealthGrid 2006 Conf., Valencia, Spain, Stud Health Technol. Inf., vol. 120, pp. 247-58, Jun. 6-8.
    • Proc. HealthGrid 2006 Conf , vol.120 , pp. 247-258
    • Tsiknakis, M.1    Kafetzopoulos, D.2    Potamias, G.3    Marias, C.4    Analyti, A.5    Manganas, A.6
  • 4
    • 10444280524 scopus 로고    scopus 로고
    • Proteus, a grid based problem solving environment for bioinformatics: Architecture and experiments
    • Feb
    • M. Cannataro, C. Comito, F. L. Schiavo, and P. Veltri, "Proteus, a grid based problem solving environment for bioinformatics: Architecture and experiments," IEEE Comput. Intell. Bull., vol. 3, no. 1, pp. 7-18, Feb. 2004.
    • (2004) IEEE Comput. Intell. Bull , vol.3 , Issue.1 , pp. 7-18
    • Cannataro, M.1    Comito, C.2    Schiavo, F.L.3    Veltri, P.4
  • 5
    • 3242730382 scopus 로고    scopus 로고
    • Alternative pathways of galactose assimilation: Could inverse metabolic engineering provide an alternative to galactosemic patients?
    • K. Lai and M. Klapa, "Alternative pathways of galactose assimilation: Could inverse metabolic engineering provide an alternative to galactosemic patients?," Metab. Eng., vol. 6, pp. 239-244, 2004.
    • (2004) Metab. Eng , vol.6 , pp. 239-244
    • Lai, K.1    Klapa, M.2
  • 6
    • 0345871265 scopus 로고    scopus 로고
    • The quest of the mechanisms of life
    • M. Klapa and J. Quachenbush, "The quest of the mechanisms of life," Biotechnol. Bioeng., vol. 84, pp. 739-742, 2003.
    • (2003) Biotechnol. Bioeng , vol.84 , pp. 739-742
    • Klapa, M.1    Quachenbush, J.2
  • 9
    • 33646874546 scopus 로고    scopus 로고
    • Z. Hu, C. Fan, D. S. Oh, J. S. Marron, X. He, B. F. Qaqish, C. Livasy, L. A. Carey, E. Reynolds, L. Dressler, A. Nobel, J. Parker, M. G. Ewend, L. R. Sawyer, J. Wu, Y Liu, R. Nanda, M. Tretiakova, A. Ruiz Orrico, D. Dreher, J. P. Palazzo, L. Perreard, E. Nelson, M. Mone, H. Hansen, M. Mullins, J. F. Quackenbush, M. J. Ellis, O. I. Olopade, P. S. Bernard, and C. M. Perou, The molecular portraits of breast tumors are conserved across microarray platforms, BMC Genomics, 27, no. 7, p. 96, Apr. 2006.
    • Z. Hu, C. Fan, D. S. Oh, J. S. Marron, X. He, B. F. Qaqish, C. Livasy, L. A. Carey, E. Reynolds, L. Dressler, A. Nobel, J. Parker, M. G. Ewend, L. R. Sawyer, J. Wu, Y Liu, R. Nanda, M. Tretiakova, A. Ruiz Orrico, D. Dreher, J. P. Palazzo, L. Perreard, E. Nelson, M. Mone, H. Hansen, M. Mullins, J. F. Quackenbush, M. J. Ellis, O. I. Olopade, P. S. Bernard, and C. M. Perou, "The molecular portraits of breast tumors are conserved across microarray platforms," BMC Genomics, vol. 27, no. 7, p. 96, Apr. 2006.
  • 12
    • 13844310310 scopus 로고    scopus 로고
    • Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer
    • Feb
    • Y Wang, J. G. Klijn, Y Zhang, Y. Zhang, A. M. Sieuwerts, M. P. Look, F. Yang, D. Talantov, and J. A. Foekens, "Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer," Lancet, vol. 365, no. 9460, pp. 671-679, Feb. 2005.
    • (2005) Lancet , vol.365 , Issue.9460 , pp. 671-679
    • Wang, Y.1    Klijn, J.G.2    Zhang, Y.3    Zhang, Y.4    Sieuwerts, A.M.5    Look, M.P.6    Yang, F.7    Talantov, D.8    Foekens, J.A.9
  • 15
    • 33746887084 scopus 로고    scopus 로고
    • Molecular signatures predict outcome of breast cancer
    • J. A. O'Shaughnessy, "Molecular signatures predict outcome of breast cancer," N. Engl. J. Med., vol. 355, pp. 615-617, 2006.
    • (2006) N. Engl. J. Med , vol.355 , pp. 615-617
    • O'Shaughnessy, J.A.1
  • 18
    • 1542287820 scopus 로고    scopus 로고
    • In silico radiation oncology: Combining novel simulation algorithms with current visualization techniques
    • Nov
    • G. S. Stamatakos, D. D. Dionysiou, E. I. Zacharaki, N. A. Mouravliansky, K. Nikita, and N. Uzunoglu, "In silico radiation oncology: Combining novel simulation algorithms with current visualization techniques," Proc. IEEE, vol. 90, no. 11, pp. 1764-1777, Nov. 2002.
    • (2002) Proc. IEEE , vol.90 , Issue.11 , pp. 1764-1777
    • Stamatakos, G.S.1    Dionysiou, D.D.2    Zacharaki, E.I.3    Mouravliansky, N.A.4    Nikita, K.5    Uzunoglu, N.6
  • 20
    • 41549106111 scopus 로고    scopus 로고
    • W3C working draft. (2003, May 14). Web services architecture. [Online]. Available: http://www.w3.org/TR/2003/WD-ws-arch-20030514/
    • W3C working draft. (2003, May 14). Web services architecture. [Online]. Available: http://www.w3.org/TR/2003/WD-ws-arch-20030514/
  • 22
    • 0037337307 scopus 로고    scopus 로고
    • A systematic approach to modelling capturing and disseminating proteomics experimental data
    • C. F. Taylor, "A systematic approach to modelling capturing and disseminating proteomics experimental data," Nat. Biotechnol., vol. 21, pp. 247-254, 2003.
    • (2003) Nat. Biotechnol , vol.21 , pp. 247-254
    • Taylor, C.F.1
  • 23
    • 41549148513 scopus 로고    scopus 로고
    • Available:, Accessed Nov. 2007
    • Globus ToolkitH4.0: Security Available: http://www.globus.org/toolkit/ docs/4.0/security/. Accessed Nov. 2007.
    • Globus ToolkitH4.0: Security
  • 24
    • 18244404282 scopus 로고    scopus 로고
    • Service oriented science
    • May
    • I. Foster, "Service oriented science," Science, vol. 308, no. 5723, pp. 814-817, May 2005.
    • (2005) Science , vol.308 , Issue.5723 , pp. 814-817
    • Foster, I.1
  • 25
    • 85024279627 scopus 로고    scopus 로고
    • Describing the elephant: The different faces of it as service
    • I. Foster and S. Tuecke, "Describing the elephant: The different faces of it as service," ACM Queue, vol. 3, no. 6, pp. 26-29, 2005.
    • (2005) ACM Queue , vol.3 , Issue.6 , pp. 26-29
    • Foster, I.1    Tuecke, S.2
  • 26
    • 41549095244 scopus 로고    scopus 로고
    • Available:, Accessed Nov. 2007
    • The Gridge Toolkit. Available: http://www.gridge.org. Accessed Nov. 2007.
    • The Gridge Toolkit
  • 27
    • 41549106537 scopus 로고    scopus 로고
    • The OGSA-DAI project. Available:, Accessed Nov. 2007
    • The OGSA-DAI project. Available: http://www.ogsadai.org.uk/. Accessed Nov. 2007.
  • 28
    • 41549125274 scopus 로고    scopus 로고
    • OGSA-Webdb: An OGSA-based system for bringing web databases into the grid
    • Jun
    • M. P. Said and I. Kojima, "OGSA-Webdb: An OGSA-based system for bringing web databases into the grid," J. Digit. Inf. Manag., vol. 2, no. 2, pp. 48-53, Jun. 2004.
    • (2004) J. Digit. Inf. Manag , vol.2 , Issue.2 , pp. 48-53
    • Said, M.P.1    Kojima, I.2
  • 29
    • 0032026995 scopus 로고    scopus 로고
    • Knowledge engineering: Principles and methods
    • Mar
    • R. Studer, V. R. Benjamins, and D. Fensel, "Knowledge engineering: Principles and methods," IEEE Digit. Inf. Manag., vol. 25, no. 1/2, pp. 161-197, Mar. 1998.
    • (1998) IEEE Digit. Inf. Manag , vol.25 , Issue.1-2 , pp. 161-197
    • Studer, R.1    Benjamins, V.R.2    Fensel, D.3
  • 30
    • 0002433547 scopus 로고    scopus 로고
    • From data mining to knowledge discovery: An overview
    • U. Fayyad, G. Piatetsky-Shapiro, P. Smyth, and R. Uthurusamy, Eds. Menlo Park, CA: AAAI Press
    • U. Fayyad, G. Piatetsky-Shapiro, and P. Smyth, "From data mining to knowledge discovery: An overview," in Advances in Knowledge Discovery and Data Mining, U. Fayyad, G. Piatetsky-Shapiro, P. Smyth, and R. Uthurusamy, Eds. Menlo Park, CA: AAAI Press, 1996, pp. 1-30.
    • (1996) Advances in Knowledge Discovery and Data Mining , pp. 1-30
    • Fayyad, U.1    Piatetsky-Shapiro, G.2    Smyth, P.3
  • 32
    • 41549150587 scopus 로고    scopus 로고
    • Foundation Model of Auatomy FMA, Available:, Accessed Nov. 2007
    • Foundation Model of Auatomy (FMA). Available: http:// sig.biostr.washington.edu/projects/fm/AboutFM.html. Accessed Nov. 2007.
  • 33
    • 84888293115 scopus 로고    scopus 로고
    • Available:, Accessed Nov. 2007
    • The Gene Ontology (GO). Available: http://geneontology.org/. Accessed Nov. 2007.
    • The Gene Ontology (GO)
  • 35
    • 80255137862 scopus 로고    scopus 로고
    • An ontology for carcinoma classification for clinical bioinformatics
    • Geneva, Switzerland, pp
    • A. Kumar, Y. L. Yip, B. Smith, D. Marwede, and D. Novotny, "An ontology for carcinoma classification for clinical bioinformatics," in Proc. MIE 2005, Geneva, Switzerland, pp. 635-640.
    • Proc. MIE 2005 , pp. 635-640
    • Kumar, A.1    Yip, Y.L.2    Smith, B.3    Marwede, D.4    Novotny, D.5
  • 36
    • 18944374341 scopus 로고    scopus 로고
    • Biodynamic ontology: Applying BFO in the biomedical domain
    • D. M. Pisanelli, Ed. Amsterdam, The Netherlands: IOS Press
    • P. Grenon, B. Smith, and L. Goldberg, "Biodynamic ontology: Applying BFO in the biomedical domain," in Ontologies Med., D. M. Pisanelli, Ed. Amsterdam, The Netherlands: IOS Press, 2004, pp. 20-38.
    • (2004) Ontologies Med , pp. 20-38
    • Grenon, P.1    Smith, B.2    Goldberg, L.3
  • 37
    • 41549128744 scopus 로고    scopus 로고
    • N. Zhong and J. Liu, Eds, New York: Springer-Verlag
    • N. Zhong and J. Liu, Eds., Intelligent Technologies for Information Analysis. New York: Springer-Verlag, 2004, pp. 615-659.
    • (2004) Intelligent Technologies for Information Analysis , pp. 615-659
  • 38
    • 35148839490 scopus 로고
    • A translation approach to portable ontologies
    • T. R. Gruber, "A translation approach to portable ontologies," Knowl. Acquisition, vol. 5, no. 2, pp. 199-220, 1993.
    • (1993) Knowl. Acquisition , vol.5 , Issue.2 , pp. 199-220
    • Gruber, T.R.1
  • 39
    • 18844466577 scopus 로고    scopus 로고
    • Semeda: Ontology based semantic integration of biological databases
    • Dec
    • J. Kohler, S. Philippi, and M. Lange, "Semeda: Ontology based semantic integration of biological databases," Bioinformatics, vol. 19, no. 18, pp. 2420-2427, Dec. 2003.
    • (2003) Bioinformatics , vol.19 , Issue.18 , pp. 2420-2427
    • Kohler, J.1    Philippi, S.2    Lange, M.3
  • 40
    • 0141948505 scopus 로고    scopus 로고
    • The semantic grid: A future e-science infrastructure
    • F. Berman, A. J. G. Hey, and G. E Fox, Eds. Hoboken, NJ: Wiley
    • D. D. Roure, N. R. Jennings, and N. Shadbolt, "The semantic grid: A future e-science infrastructure," in Grid Computing: Making the Global Infrastructure a Reality, F. Berman, A. J. G. Hey, and G. E Fox, Eds. Hoboken, NJ: Wiley, 2003, pp. 437-470.
    • (2003) Grid Computing: Making the Global Infrastructure a Reality , pp. 437-470
    • Roure, D.D.1    Jennings, N.R.2    Shadbolt, N.3
  • 41
    • 4243061781 scopus 로고    scopus 로고
    • Knowledge grid - An architecture for distributed knowledge discovery
    • M. Cannataro and D. Talia, "Knowledge grid - An architecture for distributed knowledge discovery," Commun. ACM, vol. 46, no. 1, pp. 89-93, 2003.
    • (2003) Commun. ACM , vol.46 , Issue.1 , pp. 89-93
    • Cannataro, M.1    Talia, D.2
  • 42
    • 41549119274 scopus 로고    scopus 로고
    • Web Service Ontology. Available:, Accessed Nov. 2007
    • Web Service Ontology. Available: http://www.ai.sri.com/daml/services/ owl-s/. Accessed Nov. 2007.
  • 43
    • 0037410107 scopus 로고    scopus 로고
    • A suite of DAML+OIL ontologies to describe bioinformatics web services and data
    • C. Wroe, R. Stevens, C. Goble, A. Roberts, and M. Greenwood, "A suite of DAML+OIL ontologies to describe bioinformatics web services and data," Int. J. Coop. Inf. Syst., vol. 12, no. 2, pp. 197-224, 2003.
    • (2003) Int. J. Coop. Inf. Syst , vol.12 , Issue.2 , pp. 197-224
    • Wroe, C.1    Stevens, R.2    Goble, C.3    Roberts, A.4    Greenwood, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.