Changes of histology and expression of MMP-2 and nm23-H1 in primary and metastatic gastric cancer

World Journal of Gastroenterology

Volumn 14, Issue 10, 2008, Pages 1612-1616

  Wang, Lin Bo ^a   Jiang, Zhi Nong ^a   Fan, Miao Ying ^a   Xu, Chao Yang ^a   Chen, Wen Jun ^a   Shen, Jian Guo ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Gastric cancer; Heterogeneity; Histological change; MMP 2; Nm23 H1

Indexed keywords

GELATINASE A; NUCLEOSIDE DIPHOSPHATE KINASE A;

ADULT; AGED; ARTICLE; CANCER CLASSIFICATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; METASTASIS POTENTIAL; PRIMARY TUMOR; STOMACH CANCER; TUMOR DIFFERENTIATION;

EID: 41549115888     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.14.1612     Document Type: Article

References (29)

1. Gentile A, Comoglio PM. Invasive growth: a genetic program. Int J Dev Biol 2004; 48: 451-456
2. Liotta LA, Kohn E. Cancer invasion and metastases. JAMA 1990; 263: 1123-1126
3. Schwartz GK. Invasion and metastases in gastric cancer: in vitro and in vivo models with clinical correlations. Semin Oncol 1996; 23: 316-324
4. Nelson AR, Fingleton B, Rothenberg ML, Matrisian LM. Matrix metalloproteinases: biologic activity and clinical implications. J Clin Oncol 2000; 18: 1135-1149
5. Passlick B, Sienel W, Seen-Hibler R, Wockel W, Thetter O, Mutschler W, Pantel K. Overexpression of matrix metalloproteinase 2 predicts unfavorable outcome in early-stage non-small cell lung cancer. Clin Cancer Res 2000; 6: 3944-3948
6. Tryggvason K, Hoyhtya M, Pyke C. Type IV collagenases in invasive tumors. Breast Cancer Res Treat 1993; 24: 209-218
7. Nomura H, Sato H, Seiki M, Mai M, Okada Y. Expression of membrane-type matrix metalloproteinase in human gastric carcinomas. Cancer Res 1995; 55: 3263-3266
8. Wu ZY, Li JH, Zhan WH, He YL. Lymph node micrometastasis and its correlation with MMP-2 expression in gastric carcinoma. World J Gastroenterol 2006; 12: 2941-2944
9. Steeg PS, Bevilacqua G, Kopper L, Thorgeirsson UP, Talmadge JE, Liotta LA, Sobel ME. Evidence for a novel gene associated with low tumor metastatic potential. J Natl Cancer Inst 1988; 80: 200-204
10. Barnes R, Masood S, Barker E, Rosengard AM, Coggin DL, Crowell T, King CR, Porter-Jordan K, Wargotz ES, Liotta LA. Low nm23 protein expression in infiltrating ductal breast carcinomas correlates with reduced patient survival. Am J Pathol 1991; 139: 245-250
11. Ayhan A, Yasui W, Yokozaki H, Kitadai Y, Tahara E. Reduced expression of mn23 protein is associated with advanced tumor stage and distant metastases in human colorectal carcinomas. Virchows Arch B Cell Pathol Incl Mol Pathol 1993; 63: 213-218
12. Charpin C, Garcia S, Bonnier P, Martini F, Andrac L, Horschowski N, Lavaut MN, Allasia C. Prognostic significance of Nm23/NDPK expression in breast carcinoma, assessed on 10-year follow-up by automated and quantitative immunocytochemical assays. J Pathol 1998; 184: 401-407
13. Lichy JH, Dalbegue F, Zavar M, Washington C, Tsai MM, Sheng ZM, Taubenberger JK. Genetic heterogeneity in ductal carcinoma of the breast. Lab Invest 2000; 80: 291-301
14. Yamasaki M, Takeshima Y, Fujii S, Matsuura M, Tagawa K, Inai K. Correlation between morphological heterogeneity and genetic alteration within one tumor in adenocarcinomas of the lung. Pathol Int 2000; 50: 891-896
15. Kuukasjarvi T, Karhu R, Tanner M, Kahkonen M, Schaffer A, Nupponen N, Pennanen S, Kallioniemi A, Kallioniemi OP, Isola J. Genetic heterogeneity and clonal evolution underlying development of asynchronous metastasis in human breast cancer. Cancer Res 1997; 57: 1597-1604
16. Ling V, Chambers AF, Harris JF, Hill RP. Dynamic heterogeneity and metastasis. J Cell Physiol Suppl 1984; 3: 99-103
17. Naito S, Walker SM, von Eschenbach AC, Fidler IJ. Evidence for metastatic heterogeneity of human renal cell carcinoma. Anticancer Res 1988; 8: 1163-1167
18. Kubben FJ, Sier CF, van Duijn W, Griffioen G, Hanemaaijer R, van de Velde CJ, van Krieken JH, Lamers CB, Verspaget HW. Matrix metalloproteinase-2 is a consistent prognostic factor in gastric cancer. Br J Cancer 2006; 94: 1035-1040
19. Schwartz GK, Wang H, Lampen N, Altorki N, Kelsen D, Albino AP. Defining the invasive phenotype of proximal gastric cancer cells. Cancer 1994; 73: 22-27
20. Ji F, Chen YL, Jin EY, Wang WL, Yang ZL, Li YM. Relationship between matrix metalloproteinase-2 mRNA expression and clinicopathological and urokinase-type plasminogen activator system parameters and prognosis in human gastric cancer. World J Gastroenterol 2005; 11: 3222-3226
21. Zhang H, Morisaki T, Matsunaga H, Sato N, Uchiyama A, Hashizume K, Nagumo F, Tadano J, Katano M. Protein-bound polysaccharide PSK inhibits tumor invasiveness by down-regulation of TGF-beta1 and MMPs. Clin Exp Metastasis 2000; 18: 343-352
22. Denkert C, Siegert A, Leclere A, Turzynski A, Hauptmann S. An inhibitor of stress-activated MAP-kinases reduces invasion and MMP-2 expression of malignant melanoma cells. Clin Exp Metastasis 2002; 19: 79-85
23. Gilles AM, Presecan E, Vonica A, Lascu I. Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme. J Biol Chem 1991; 266: 8784-8789
24. Seifert M, Welter C, Mehraein Y, Seitz G. Expression of the nm23 homologues nm23-H4, nm23-H6, and nm23-H7 in human gastric and colon cancer. J Pathol 2005; 205: 623-632
25. Charpin C, Garcia S, Bonnier P, Martini F, Andrac L, Horschowski N, Lavaut MN, Allasia C. Prognostic significance of Nm23/NDPK expression in breast carcinoma, assessed on 10-year follow-up by automated and quantitative immunocytochemical assays. J Pathol 1998; 184: 401-407
26. Nakayama H, Yasui W, Yokozaki H, Tahara E. Reduced expression of nm23 is associated with metastasis of human gastric carcinomas. Jpn J Cancer Res 1993; 84: 184-190
27. Hsu NY, Chow KC, Chen WJ, Lin CC, Chou FF, Chen CL. Expression of nm23 in the primary tumor and the metastatic regional lymph nodes of patients with gastric cardiac cancer. Clin Cancer Res 1999; 5: 1752-1757
28. Wang CS, Lin KH, Hsu YC, Hsueh S. Distant metastasis of gastric cancer is associated with elevated expression of the antimetastatic nm23 gene. Cancer Lett 1998; 128: 23-29
29. Yeung P, Lee CS, Marr P, Sarris M, Fenton-Lee D. Nm23 gene expression in gastric carcinoma: an immunohistochemical study. Aust N Z J Surg 1998; 68: 180-182