Conformational rearrangement within the soluble domains of the CD4 receptor is ligand-specific

Journal of Biological Chemistry

Volumn 283, Issue 5, 2008, Pages 2761-2772

  Ashish, ^a   Juncadella, Ignacio J ^b   Garg, Renu ^a   Boone, Christopher D ^a   Anguita, Juan ^b   Krueger, Joanna K ^a  

^a UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE   (United States)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; FLOW INTERACTIONS; LIGANDS;

AB INITIO; CONFORMATIONAL CHANGES; CONFORMATIONAL REARRANGEMENTS; CYTOPLASMIC DOMAINS; DO-MAINS; ENVELOPE PROTEINS; EXTRACELLULAR LOOPS; GLYCOPROTEIN LIGANDS; IMMUNE SIGNALING; LIGAND BINDINGS; SHAPE CHANGES; SHARP CONTRASTS; SMALL ANGLE X-RAY SCATTERINGS; SOLUBLE DOMAINS; STRUCTURAL REARRANGEMENTS;

CONFORMATIONS;

CD4 ANTIGEN; GLYCOPROTEIN; GLYCOPROTEIN GP 120; LYMPHOCYTE ANTIGEN RECEPTOR; LYMPHOCYTE ENZYME; SALP 15; UNCLASSIFIED DRUG; GP120 PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; LIGAND; RECOMBINANT PROTEIN; SALIVA PROTEIN; SALP15 PROTEIN, IXODES SCAPULARIS;

AB INITIO CALCULATION; ANIMAL CELL; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOPLASM; DISSOCIATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; VIRUS ENTRY; X RAY CRYSTALLOGRAPHY; ANIMAL; BAGG ALBINO MOUSE; C3H MOUSE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; IMMUNOLOGY; IN VITRO STUDY; LYMPHOCYTE ACTIVATION; METABOLISM; MOUSE; PROTEIN TERTIARY STRUCTURE; SMALL ANGLE SCATTERING; SOLUBILITY; T LYMPHOCYTE; X RAY DIFFRACTION;

HUMAN IMMUNODEFICIENCY VIRUS 1; IXODIDA;

ANIMALS; ANTIGENS, CD4; HIV ENVELOPE PROTEIN GP120; HUMANS; LIGANDS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SALIVARY PROTEINS; SCATTERING, SMALL ANGLE; SOLUBILITY; T-LYMPHOCYTES; X-RAY DIFFRACTION;

EID: 41449119309     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M708325200     Document Type: Article

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