Oral lesions and immune reconstitution syndrome in HIV+/AIDS patients receiving highly active antiretroviral therapy. Epidemiological evidence

Medicina Oral, Patologia Oral y Cirugia Bucal

Volumn 13, Issue 2, 2008, Pages 85-93

  Gaitan Cepeda, Luis A ^a   Ceballos Salobreña, Alejandro ^b,e   López Ortega, Karem ^c   Arzate Mora, Nancy ^a   Jiménez Soriano, Yolanda ^d  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b UNIVERSITY OF GRANADA   (Spain)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d Doctor of Stomatology   (Spain)

^e NONE   (Spain)

Author keywords

AIDS; HIV; Immune reconstitution inflammatory syndrome; Oral lesions

Indexed keywords

PROTEINASE INHIBITOR; RNA DIRECTED DNA POLYMERASE INHIBITOR;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; AGE; ARTICLE; CANDIDIASIS; CD4 LYMPHOCYTE COUNT; CHEILITIS; DRUG ABUSE; FEMALE; GENDER; HETEROSEXUALITY; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME; KAPOSI SARCOMA; LEUKOPLAKIA; LIP HERPES; MAJOR CLINICAL STUDY; MALE; MALE HOMOSEXUAL; MOUTH LESION; MYCOSIS; PREVALENCE; SPAIN; TREATMENT DURATION; VIRUS LOAD; MICROBIOLOGY; MIDDLE AGED; MOUTH DISEASE; OPPORTUNISTIC INFECTION;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ADULT; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; FEMALE; HIV SEROPOSITIVITY; HUMANS; IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME; MALE; MIDDLE AGED; MOUTH DISEASES; OPPORTUNISTIC INFECTIONS; PREVALENCE;

EID: 41449118758     PISSN: 16984447     EISSN: 16986946     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Mittler JE, Levin BR, Antia R. T-cell homeostasis, competition, and drift: AIDS as HIV-accelerated senescence of the immune repertoire. J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Jul;12(3):233-48.
2. Levin BR, Bull JJ, Stewart FM. Epidemiology, evolution, and future of the HIV/AIDS pandemic. Emerg Infect Dis. 2001;7(3 Suppl):505-11
3. Antia R, Halloran ME. Recent developments in theories of pathogenesis of AIDS. Trends Microbiol. 1996 Jul;4(7):282-5
4. Lawn SD, Wilkinson RJ. Immune reconstitution disease associated with parasitic infections following antiretroviral treatment. Parasite Immunol. 2006 Nov;28(11):625-33
5. Murdoch DM, Venter WDF, Van Rie A, Feldam C. Immune reconstitution inflammatory syndrome (IRIS): a review of common infectious manifestations and treatment options. AIDS Research Ther 2007 May 8;4:9 Available at: http://www.aidsrestherapy.eom/content/4/1/9.
6. Cheng VCC, Yuen K, Chan W, Wong SYS, Ma ESK, Chan RMT. Immunorestitution disease involving the innate and adaptive response. Clin Infect Dis. 2000;30:882-92.
7. Feller L, Wood NH, Lemmer J. Herpes zoster infection as an immune reconstitution inflammatory syndrome in HIV-seropositive subjects: A review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Jun 27. Available at: http:/ 10.1016/j.tripleo.2007.02.001.
8. Ramírez-Amador V, Ponce-De-León S, Sierra-Madero J, Soto-Ramírez L, Esquivel-Pedraza L, Anaya-Saavedra G. Synchronous kinetics of CD4+ lymphocytes and viral load before the onset of oral candidosis and hairy leukoplakia in a cohort of Mexican HIV-infected patients. AIDS Res Hum Retroviruses. 2005 Dec;21(12):981-90
9. Fernández-Feijoo J, Diz-Dios P, Otero-Cepeda XL, Limeres-Posse J, de la Fuente-Aguado J, Ocampo-Hermida A. Predictive value of oral candidiasis as a marker of progression to AIDS.Med Oral Patol Oral Cir Bucal. 2005 Jan-Feb;10(1):36-40; 32-6.
10. Gaitán-Cepeda LA, Martínez-González M, Ceballos-Salobreña A. Oral candidosis as a clinical marker of immune failure in patients with HIV/AIDS on HAART. AIDS Patient Care STDS. 2005 Feb;19(2):70-7
11. Aguirre JM, Echebarria MA, Ocina E, Ribacoba L, Montejo M. Reduction of HIV-associated oral lesions after highly active antiretroviral therapy. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999 Aug;88(2):114-5.
12. Kroidl A, Schaeben A, Oette M, Wettstein M, Herfordt A, Häussinger D. Prevalence of oral lesions and periodontal diseases in HIV-infected patients on antiretroviral therapy. Eur J Med Res. 2005 Oct 18;10(10):448-53.
13. Cauda R, Tacconelli E, Tumbarello M, Morace G, De Bernardis F, Torosantucci A, et al. Role of protease inhibitors in preventing recurrent oral candidosis in patients with HIV infection: a prospective case-control study. J Acquir Immune Defic Syndr. 1999 May 1;21(1):20-5.
14. Ceballos-Salobreña A, Gaitán-Cepeda LA, Ceballos-Garcia L, Lezama-Del Valle D. Oral lesions in HIV/AIDS patients undergoing highly active antiretroviral treatment including protease inhibitors: a new face of oral AIDS? AIDS Patient Care STDS. 2000 Dec;14(12):627-35.
15. Nicolatou-Galitis O, Velegraki A, Paikos S, Economopoulou P, Stefaniotis T, Papanikolaou IS, et al. Effect of PI-HAART on the prevalence of oral lesions in HIV-1 infected patients. A Greek study. Oral Dis. 2004 May;10(3):145-50.
16. Umadevi KMR, Ranganathan K, Pavithra S, Hemalatha R, Saraswathi TR, Kumarasamy N, et al. Oral lesions among persons with HIV disease with and without highly active antiretroviral therapy in southern India. J Oral Pathology & Med. 2007; 36(3):136-141.
17. Schmidt-Westhausen AM, Priepke F, Bergmann FJ, Reichart PA. Decline in the rate of oral opportunistic infections following introduction of highly active antiretroviral therapy. J Oral Pathol Med. 2000 Aug;29(7):336-41.
18. Emery S, Lane HC. Immune reconstitution in HIV infection. Curr Opin Immunol. 1997 Aug;9(4):568-72.
19. Shelburne SA, Visnegarwala F, Darcourt J, Graviss EA, Giordano TP, White AC Jr, et al. Incidence and risk factors for immune reconstitution inflammatory syndrome during highly active antiretroviral therapy. AIDS. 2005 Mar 4;19(4):399-406.
20. Lehloenya R, Meintjes G: Dermatologic manifestations of the immune reconstitution inflammatory syndrome. Dermatol Clin. 2006 Oct;24(4):549-70.
21. Pereira B, Fernandes C, Nachiambo E, Catarino MC, Rodrigues A, Cardoso J. Exuberant molluscum contagiosum as a manifestation of the immune reconstitution inflammatory syndrome. Dermatol Online J. 2007 May 1;13(2):6.
22. Bower M, Nelson M, Young AM, Thirlwell C, Newsom-Davis T, Mandalia S, et al. Immune reconstitution inflammatory syndrome associated with Kaposi's sarcoma. J Clin Oncol. 2005 Aug 1;23(22):5224-8.
23. Flint SR, Tappuni A, Leigh J, Schmidt-Westhausen AM, MacPhail L. Markers of immunodeficiency and mechanisms of HAART therapy on oral lesions. Adv Dent Res. 2006 Apr 1;19(1):146-51.
24. Miziara ID, Weber R. Oral candidosis and oral hairy leukoplakia as predictors of HAART failure in Brazilian HIV-infected patients. Oral Dis. 2006 Jul;12(4):402-7.
25. Patton LL. Sensitivity, specificity, and positive predictive value of oral opportunistic infections in adults with HIV/AIDS as markers of immune suppression and viral burden. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000 Aug;90(2):182-8.
26. Miller CS, Berger JR, Mootoor Y, Avdiushko SA, Zhu H, Kryscio RJ. High prevalence of multiple human herpesviruses in saliva from human immunodeficiency virus-infected persons in the era of highly active antiretroviral therapy. J Clin Microbiol. 2006 Jul;44(7):2409-15.
27. Leigh JE, Shetty K, Fidel PL Jr.: Oral opportunistic infections in HIV-positive individuals: review and role of mucosal immunity. AIDS Patient Care STDS. 2004 Aug;18(8):443-56.
28. Surjushe AU, Jindal SR, Kamath RR, Saple DG. Immune reconstitution inflammatory syndrome. Indian J Dermatol Venereol Leprol. 2006 Nov-Dec;72(6):410-4.
29. Cassone A, De Bernardis F, Torosantucci A, Tacconelli E, Tumbarello M, Cauda R. In vitro and in vivo anticandidal activity of human immunodeficiency virus protease inhibitors. J Infect Dis. 1999 Aug;180(2):448-53.
30. Sroussi HY, Villines D, Epstein J, Alves MC, Alves ME: Oral lesions in HIV-positive dental patients-one more argument for tobacco smoking cessation. Oral Dis. 2007 May;13(3):324-8.
31. Hamza OJ, Matee MI, Simon EN, Kikwilu E, Moshi MJ, Mugusi F. Oral manifestations of HIV infection in children and adults receiving highly active anti-retroviral therapy [HAART] in Dar es Salaam, Tanzania. BMC Oral Health. 2006 Aug 18;6:12.