Cervical cytology specimen adequacy: Patient management guidelines and optimizing specimen collection

Journal of Lower Genital Tract Disease

Volumn 12, Issue 2, 2008, Pages 71-81

  Davey, Diane Davis ^a,i   Cox, J Thomas ^b   Austin, R Marshall ^c   Birdsong, George ^d   Colgan, Terence J ^e   Howell, Lydia P ^f   Husain, Mujtaba ^g   Darragh, Teresa M ^h  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e MOUNT SINAI HOSPITAL   (Canada)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h UNIVERSITY OF CALIFORNIA   (United States)

ⁱ UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Bethesda terminology; Cervical cytology screening; Guidelines; Management; Pap test; Specimen adequacy; Unsatisfactory

Indexed keywords

ARTICLE; CANCER SCREENING; CONTROLLED STUDY; FEMALE; FOLLOW UP; HUMAN; PAPANICOLAOU TEST; PATIENT CARE; PATIENT SATISFACTION; UTERINE CERVIX CANCER; UTERINE CERVIX CYTOLOGY; WART VIRUS;

FEMALE; HUMANS; MASS SCREENING; PRACTICE GUIDELINES AS TOPIC; QUALITY INDICATORS, HEALTH CARE; SPECIMEN HANDLING; UTERINE CERVICAL NEOPLASMS; VAGINAL SMEARS;

EID: 41449109559     PISSN: 10892591     EISSN: None     Source Type: Journal    
DOI: 10.1097/LGT.0b013e3181585b9b     Document Type: Article

References (63)

1. Davey DD, Austin RM, Birdsong G, Buck HW, Cox JT, Darragh TM, et al. ASCCP patient management guidelines: Pap test specimen adequacy and quality indicators. J Low Genit Tract Dis 2002;6:195-9.
2. Birdsong GG, Davey DD, Darragh TM, Elgert PA, Henry M. Specimen adequacy. In: Solomon D, Nayar R, eds. The Bethesda System for Reporting Cervical Cytology. Springer-Verlag: New York; 2004:1-20.
3. Wright TC, Cox JT, Massad LS, Twiggs LB, Wilkinson EJ. 2001 ASCCP-Sponsored Consensus Conference. 2001 Consensus guidelines for the management of women with cervical cytological abnormalities. JAMA 2002;287:2120-9.
4. ACOG Practice Bulletin No. 45. Clinical management guidelines for obstetrician-gynecologists: cervical cytology screening. Obstet Gynecol 2003;102:417-27.
5. Fetters MD, Lieberman RW, Abrahamse PH, Sanghvi RV, Sonnad SS. Cost-effectiveness of Pap smear screening for vaginal cancer after total hysterectomy for benign disease. J Low Genit Tract Dis 2003;7:194-202.
6. Pearce KF, Haefner HK, Sarwar SF, Nolan TE. Cytopathological findings on vaginal Papanicolaou smears after hysterectomy for benign gynecologic disease. N Engl J Med 1996;335:1559-62.
7. Saslow D, Runowicz CD, Solomon D, Moscicki AB, Smith RA, Eyre HJ, et al. American Cancer Society guideline for the early detection of cervical neoplasia and cancer. CA Cancer J Clin 2002;52:342-62.
8. Hock YL, Ramaiah S, Wall ES, Harris AM, Marston L, Marshall J, et al. Outcome of women with inadequate cervical smears followed up for five years. J Clin Pathol 2003;56:592-5.
9. Ransdell JS, Davey DD, Zaleski S. Clinicopathologic correlation of the unsatisfactory Papanicolaou smear. Cancer (Cancer Cytopathol) 1997;81:139-43.
10. Cooper AL, Dornfeld-Finke JM, Banks HW, Davey DD, Modesitt SC. Is cytologic screening an effective surveillance method for detection of vaginal recurrence of uterine cancer? Obstet Gynecol 2006;107:71-6.
11. Sawaya GF, Grady D, Kerlikowske K, La Valleur J, Barnabei VM, Bass K, et al. The positive predictive value of cervical smears in previously screened postmenopausal women: the Heart and Estrogen/Progestin Replacement Study (HERS). Ann Intern Med 2000;133:942-50.
12. Adams AL, Gidley J, Roberson J, Wang W, Eltoum I, Chhieng DC. Clinical significance of unsatisfactory conventional smears owing to inadequate squamous cellularity defined by the Bethesda 2001 criterion. Am J Clin Pathol 2005;123:738-43.
13. McQueen F, Duvall E. Using a quality control approach to define an adequately cellular liquid-based cervical cytology specimen. Cytopathology 2006;17:168-74.
14. Martin-Hirsch P, Lilford R, Jarvis G, Kitchener H. Efficacy of cervical-smear collection devices: a systematic review and meta-analysis. Lancet 1999;354:1763-70.
15. Mitchell HS. Longitudinal analysis of histologic high-grade disease after negative cervical cytology according to endocervical status. Cancer (Cancer Cytopathol) 2001;93:237-40.
16. Baer A, Kiviat NB, Kulasingam S, Mao C, Kuypers J, Koutsky LA. Liquid-based Papanicolaou smears without a transformation zone component: should clinicians worry? Obstet Gynecol 2002;99:1053-9.
17. Smith HO, Tiffany MF, Qualls CR, Key CF. The rising incidence of adenocarcinoma relative to squamous cell carcinoma of the uterine cervix in the United States: a 24-year population-based study. Gynecol Oncol 2000;78:97-105.
18. Castle PE, Wacholder S, Sherman ME, Lorincz AT, Glass AG, Scott DR, et al. Absolute risk of a subsequent abnormal Pap among oncogenic human papillomavirus DNA-positive, cytologically negative women. Cancer 2002;95:2145-51.
19. Navina S, Savid K, Miller L, McKeon D, Wang X, Gulbahce E, et al. The effect of the presence of an adequate EC/TZ component on the detection of the high risk HPV (hr-HPV) DNA. A study of 7,990 cases classified by the 2001 Bethesda System. Cancer (Cancer Cytopathol) 2006;108:397.
20. Jastania R, Geddie WR, Chapman W, Boerner S. Characteristics of apparently false negative digene hybrid capture 2 high-risk HPV DNA testing. Am J Clin Pathol 2006;125:223-8.
21. Eltoum IA, Chhieng DC, Crowe DR, Roberson J, Jin G, Broker TR. Significance and possible causes of false-negative results of reflex human papillomavirus testing. Cancer (Cancer Cytopathol) 2007;111:154-9.
22. Depuydt CE, Benov IH, Bailleul EJ, Vandepitte J, Vereecken AJ, Bogers JJ. Improved endocervical sampling and HPV viral load detection by Cervex-Brush Combi. Cytopathology 2006;17:374-81.
23. Zuna RE, Wang SS, Rosenthal DL, Jeronimo J, Schiffman M, Solomon D, et al. Determinants of human papillomavirus-negative low-grad squamous intraepithelial lesions in the atypical squamous cells of undetermined significance/low-grade squamous intraepithelial lesions triage study (ALTS). Cancer (Cancer Cytopathol) 2005;105:253-62.
24. Sherman ME, Carreon JD, Schiffman M. Performance of cytology and human papillomavirus testing in relation to the menstrual cycle. Br J Cancer 2006;94:1160-6.
25. Anderson S, Larson B, Hjerpe A, Silfversward C, Sallstrom J, Wilander E, et al. Adenocarcinoma of the uterine cervix: the presence of human papillomavirus and the method detection. Acta Obstet Gynecol Scand 2003;82:960-5.
26. Bergstrom R, Sparen P, Adami H-O. Trends in cancer of the cervix uteri in Sweden following cytological screening. Br J Cancer 1999;81:159-66.
27. Bulk S, Visser O, Rozendaal L, Veerheijen RH, Meijer CJ. Incidence and survival rate of women with cervical cancer in the Greater Amsterdam area. Br J Cancer 2003;89:834-9.
28. Liu S, Semenciw R, Probert A, Mao Y. Cervical cancer in Canada: changing patterns in incidence and mortality. Int J Gynecol Cancer 2001;11:24-31.
29. Mitchell H, Medley G, Gordon J, Giles G. Cervical cytology reported as negative and risks of adenocarcinoma of the cervix: no strong evidence of benefit. Br J Cancer 1995;71:894-7.
30. Nieminen P, Kallio M, Anttila A, Hakama M. Organized vs. spontaneous Pap-smear screening for cervical cancer: a case-control study. Int J Cancer 1999;83:55-8.
31. Wang SS, Sherman ME, Hildesheim A, Lacey JV, Devesa S. Cervical adenocarcinoma and squamous cell carcinoma incidence trends among white women and black women in the United States for 1976-2000. Cancer 2004;100:1035-44.
32. Renshaw AA, Mody DR, Lozano RL, Volk EE, Walsh MK, Davey DD, et al. Detection of adenocarcinoma in situ of the cervix in Papanicolaou tests: comparison of diagnostic accuracy with other high-grade lesions. Arch Pathol Lab Med 2004;128:153-7.
33. Alfsen GC, Thoresen SO, Kristensen GB, Skovlund E, Abeler VM. Histopathologic subtyping of cervical adenocarcinoma reveals increasing incidence rates of endometrioid tumors in all age groups. Cancer 2000;89:1291-9.
34. Armstrong B, Holam D. Increasing mortality from cancer of the cervix in young Australian women. Med J Aust 1981;1:460-2.
35. Sasieni P, Adams J. Changing rates of adenocarcinoma and adenosquamous carcinoma of the cervix in England. Lancet 2001;357:1490-3.
36. Vizcaino AP, Moreno V, Bosch FX, Munoz N, Barros-Dios XM, Parkin DM. International trends in the incidence of cervical cancer. I. Adenocarcinoma and adenosquamous cell carcinomas. Int J Cancer 1998;75:536-45.
37. Zheng T, Holford TR, Ma Z, Chen Y, Liu W, Ward BA, et al. The continuing increase in adenocarcinoma of the uterine cervix: a birth cohort phenomenon. Int J Epidemiol 1996;25:252-8.
38. Howlett R, Marrett L, Innes M, Rosen B, McLachlin CM. Decreasing incidence of cervical adenocarcinoma in Ontario: is this related to improved endocervical Pap test sampling? Int J Cancer 2006;120:362-7.
39. Mitchell H, Hocking J, Saville M. Improvement in protection against adenocarcinoma of the cervix resulting from participation in cervical screening. Cancer (Cancer Cytopathol) 2003;99:336-41.
40. Romero AA, Key CR, Smith HO. Changing trends in adenocarcinoma and squamous cell carcinoma by age, race and stage: a 25-year population-based study. Gynecol Oncol 2001;80:295-6.
41. Hecht JL, Sheets EE, Lee KR. Atypical glandular cells of undetermined significance in conventional cervical/vaginal smears and thin-layer preparations. Cancer (Cancer Cytopathol) 2002;96:1-4.
42. Schorge JO, Saboorian MH, Hynan L, Ashfaq R. ThinPrep detection of cervical and endometrial adenocarcinoma. Cancer (Cancer Cytopathol) 2002;96:338-43.
43. Solomon D, Breen N, McNeel T. Cervical cancer screening rates in the United States and the potential impact of implementation of screening guidelines. CA Cancer J Clin 2007;57:105-11.
44. Stokes-Lampard H, Wilson S, Waddell C, Ryan A, Holder R, Kehoe S. Vaginal vault smears after hysterectomy for reasons other than malignancy: a systematic review of the literature. BJOG 2006;113:1354-65.
45. Srodon M, Stoler MH, Baber GB, Kurman RJ. The distribution of low and high-risk HPV types in vulvar and vaginal intraepithelial neoplasia (VIN and VaIN). Am J Surg Pathol 2006;30:1513-8.
46. Nielsen ML, Davey DD, Kline TS. Specimen adequacy evaluation in gynecologic cytopathology: current laboratory practice in the College of American Pathologists Interlaboratory Comparison Program and tentative guidelines for future practice. Diagn Cytopathol 1993;9:394-403.
47. Cox JT. ASCCP practice guideline: management issues related to quality of the smear. J Lower Gen Tract Dis 1997;2:100-6.
48. Arbyn M, Herbert A, Schenck U, Nieminen P, Jordan J, Mcgoogan E, et al. European guidelines for quality assurance in cervical cancer screening: recommendations for collecting samples for conventional and liquid-based cytology. Cytopathology 2007;18:133-9.
49. Germain M, Heaton R, Erickson D, Henry M, Nash J, O'Connor D. A comparison of the three most common Papanicolaou smear detection techniques. Obstet Gynecol 1994;84:168-73.
50. Lai-Goldman M, Nieberg RK, Mulcahy D, Wiesmeier E. The cytobrush for evaluating routine cervicovaginal-endocervical smears. J Reprod Med 1990;35:959-63.
51. Szarewski A, Cuzick J, Singer A. Cervical smears following laser treatment. Comparison of Cervex brush versus cytobrush-Ayre spatula sampling. Acta Cytol 1991;35:76-8.
52. Amies AM, Miller L, Lee SK, Koutsky L.The effect of vaginal speculum lubrication on the rate of unsatisfactory cervical cytology diagnosis. Obstet Gynecol 2002;100:889-92.
53. Griffith WF, Stuart GS, Gluck KL, Heartwell SF. Vaginal speculum lubrication and its effects on cervical cytology and microbiology. Contraception 2005;72:60-4.
54. Prey MU. Q and A column. CAP Today. May 2007:90-3.
55. Ghanem KG, Koumans EH, Johnson RE, Sawyer MK, Papp JR, Unger ER, et al. Effect of specimen order on Chlamydia trachomatis and Neisseria gonorrhoeae test performance and adequacy of Papanicolaou smear. J Pediatr Adolesc Gynecol 2006;19:23-30.
56. Hildesheim A, Bratti CM, Edwards RP, Schiffman M, Rodriguez AC, Herrero R, et al. Collection of cervical secretions does not adversely affect Pap smears taken immediately afterward. Clin Diagn Lab Immunol 1998;5:491-3.
57. Marchand L, Mundt M, Klein G, Agarwal SC. Optimal collection technique and devices for a quality Pap smear. WMJ 2005;104:51-5.
58. Al-Awadhi RM, Mansell E, Chong S, Chow C, Singer A, Coleman DV. Video monitoring of smear-taking at colposcopy: relationship to cytology. BJOG 2004;111:967-73.
59. Jeronimo J, Castle PE, Herrero R, Sherman ME, Bratti MC, Hildesheim A, et al. Right-sided ectocervical lesions may be associated with false-negative cytology among women with histologic cervical intraepithelial neoplasia 2 or 3. J Low Genit Tract Dis 2003;7:175-83.
60. Orr JW, Barrett JM, Orr PF, Holloway RW, Holiman JL. The efficacy and safety of the cytobrush during pregnancy. Gynecol Oncol 1992;44:260-2.
61. Paraiso MF, Brady K, Helmchen R, Roat TW. Evaluation of the endocervical cytobrush and Cervex-brush in pregnant women. Obstet Gynecol 1994;84:539-43.
62. Pinto MM, Waradzin M. One-slide Papanicolaou smears prepared using combined cytobrush-spatula sampling. Acta Cytol 1989;33:705.
63. Wilbanks GD, Ikomi E, Prado RB, Richart RM. An evaluation of a one-slide cervical cytology method for the detection of cervical intraepithelial neoplasia. Acta Cytol 1968;12;157-8.