Combined repeated dose and reproductive/developmental toxicity screening test of the nitrophenolic herbicide dinoseb, 2-sec-butyl-4,6-dinitrophenol, in rats

Environmental Toxicology

Volumn 23, Issue 2, 2008, Pages 169-183

  Matsumoto, Mariko ^a   Furuhashi, Tadakazu ^b   Poncipe, Carlo ^c   Ema, Makoto ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b Nihon Bioresearch Inc   (Japan)

^c SafePharm Laboratories Ltd   (United Kingdom)

Author keywords

2 sec butyl 4,6 dinitrophenol; Dinoseb; Nitrophenolic herbicide; Rat; Repeated dose toxicity; Reproductive and developmental toxicity; Screening test; Testis toxicity

Indexed keywords

ANIMALS; HERBICIDES; PHENOLS; RATS;

NITROPHENOLIC HERBICIDE; REPEATED DOSE TOXICITY; TESTIS TOXICITY; TOXICITY SCREENING TEST;

TOXICITY;

DINOSEB;

DOSE-RESPONSE RELATIONSHIP; HERBICIDE; MORTALITY; PHENOLIC COMPOUND; PHYSIOLOGY; PREGNANCY; RODENT; SPERM; TOXICITY TEST;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEATH; DEVELOPMENTAL STAGE; EXTRAMEDULLARY HEMATOPOIESIS; FEMALE; GESTATION PERIOD; HEMATOCRIT; HEMATOLOGICAL PARAMETERS; LACTATION; MALE; MATING; NONHUMAN; ORGAN WEIGHT; PRIORITY JOURNAL; RAT; REPRODUCTIVE TOXICITY; SCREENING TEST; SEMEN ANALYSIS; SPLEEN; THIRD TRIMESTER PREGNANCY; URINALYSIS; WEIGHT GAIN;

2,4-DINITROPHENOL; ADMINISTRATION, ORAL; ANIMALS; BODY WEIGHT; DRUG SYNERGISM; FEMALE; HEMATOPOIESIS, EXTRAMEDULLARY; HERBICIDES; LITTER SIZE; MALE; MATERNAL EXPOSURE; NO-OBSERVED-ADVERSE-EFFECT LEVEL; ORGAN SIZE; PATERNAL EXPOSURE; PREGNANCY; RATS; RATS, INBRED STRAINS; REPRODUCTION; SPERM MOTILITY; SPERMATOZOA; SPLEEN; TOXICITY TESTS;

ANIMALIA; RATTUS;

EID: 41449105914     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.20321     Document Type: Article

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