A case of paraneoplastic inflammatory neuropathy of the gastrointestinal tract related to an underlying neuroblastoma: Successful management with immunosuppressive therapy

Journal of Pediatric Gastroenterology and Nutrition

Volumn 46, Issue 4, 2008, Pages 457-460

  Martin, Alessandra ^a   Messineo, Antonio ^a   Lionetti, Paolo ^a   Volta, Umberto ^b   Stanghellini, Vincenzo ^b   Barbara, Giovanni ^b   Cogliandro, Rosanna ^b   Corinaldesi, Roberto ^b   De Giorgio, Roberto ^b  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CORTICOSTEROID DERIVATIVE; METHYLPREDNISOLONE;

ABDOMINAL RADIOGRAPHY; ADOLESCENT; ADRENAL TUMOR; ARTICLE; ASPIRATION BIOPSY; BARIUM ENEMA; BONE MARROW BIOPSY; CASE REPORT; COLORECTAL ANASTOMOSIS; COMPUTER ASSISTED TOMOGRAPHY; CONSTIPATION; GASTROINTESTINAL DISEASE; GASTROINTESTINAL TRACT PARANEOPLASTIC INFLAMMATORY NEUROPATHY; HEMICOLECTOMY; HISTOPATHOLOGY; HOSPITAL ADMISSION; HOSPITAL DISCHARGE; HUMAN; ILEOSTOMY; IMMUNOSUPPRESSIVE TREATMENT; INTESTINE DISTENSION; INTESTINE OBSTRUCTION; LAPAROTOMY; MALE; MULTIPLE CYCLE TREATMENT; NEUROBLASTOMA; POSTOPERATIVE CARE; PRIORITY JOURNAL; RETROPERITONEAL TUMOR; SCOLIOSIS; SIGMOIDECTOMY; SPINE RADIOGRAPHY; THORAX RADIOGRAPHY;

ADOLESCENT; DIAGNOSIS, DIFFERENTIAL; GASTROINTESTINAL TRANSIT; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTESTINAL PSEUDO-OBSTRUCTION; MALE; NEUROBLASTOMA; PARANEOPLASTIC POLYNEUROPATHY; TREATMENT OUTCOME;

EID: 41449096975     PISSN: 02772116     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPG.0b013e31815a98ff     Document Type: Article

References (21)

1. Tanowitz HB, Kirchhoff LV, Simon D, et al. Chagas' disease. Clin Microbiol Rev 1992;5:400-19.
2. Horoupian DS, Kim Y. Encephalomyeloneuropathy with ganglionitis of the myenteric plexus in the absence of cancer. Ann Neurol 1982;6:628-32.
3. Darnell RB, Posner JB. Paraneoplastic syndromes affecting the nervous system. Semin Oncol 2006;33:270-98.
4. Shuffler MD, Baird HW, Fleming CR, et al. Intestinal pseudo-obstruction as the presenting manifestation of small cell carcinoma of the lung: a paraneoplastic neuropathy of the gastrointestinal tract. Ann Intern Med 1983;98:129-34.
5. Lennon VA, Sas DF, Busk MF, et al. Enteric neuronal autoantibodies in pseudoobstruction with small-cell lung carcinoma. Gastroenterology 1991;100:137-42.
6. Gerl A, Storck M, Schalhorn A, et al. Paraneoplastic chronic intestinal pseudo-obstruction as a rare complication of bronchial carcinoid. Gut 1992;33:1000-3.
7. Kulling D, Reed CE, Verne GN, et al. Intestinal pseudoobstruction as a paraneoplastic manifestation of malignant thymoma. Am J Gastroenterol 1997;92:1564-6.
8. Wildhaber B, Niggli F, Bergstrasser E, et al. Paraneoplastic syndromes in ganglioneuroblastoma: contrasting symtoms of constipation and diarrhoea. Eur J Pediatr 2003;162:511-3.
9. Schobinger-Clement S, Gerber HA, Stallmach T. Auto-aggressive inflammation of the myenteric plexus resulting in intestinal pseudoobstruction. Am J Surg Pathol 1999;23:602-6.
10. Conte M, Parodi S, De Bernardi B, et al. Neuroblastoma in adolescents. Cancer 2006;106:1409-17.
11. De Giorgio R, Barbara G, Stanghellini V, et al. Clinical and morphofunctional features of idiopathic myenteric ganglionitis underlying severe intestinal motor dysfunction: a study of three cases. Am J Gastroenterol 2002;97:2454-9.
12. De Giorgio R, Guerrini S, Barbara G, et al. Inflammatory neuropathies of the enteric nervous system. Gastroenterology 2004;126:1872-83.
13. Darnell RB, Posner JB. Paraneoplastic syndrome of the nervous system. N Engl J Med 2003;349:1543-54.
14. Chang BH, Koch T, Hopkins K, et al. Neuroblastoma found in a 4-year-old after rituximab therapy for opsoclonus-myoclonus. Pediatr Neurol 2006;35:213-5.
15. Smith VV, Gregson N, Foggensteiner I, et al. Acquired intestinal aganglionosis and circulating anti-neuronal antibodies without neoplasia or other neural involvement. Gastroenterology 1997;112:1366-71.
16. De Giorgio R, Camilleri M. Human enteric neuropathies: morphology and molecular pathology. Neurogastroenterol Motil 2004;16:515-31.
17. Schappi MG, Smith VV, Milla PJ, et al. Eosinophilic myenteric ganglionitis is associated with functional intestinal obstruction. Gut 2003;52:752-5.
18. Nezelof C, Vivien E, Bigel P, et al. La myosite idiopathique de l'intestin grele. Arch Fr Pediatr 1985;42:823-8.
19. Ruuska TH, Karikoski R, Smith VV, et al. Acquired myopathic intestinal pseudoobstruction may be due to autoimmune enteric leiomyositis. Gastroenterology 2002;122:1133-9.
20. Oton E, Moreira V, Redondo C, et al. Chronic intestinal pseudo-obstruction due to lymphocytic leiomyositis: is there a place for immunomodulatory therapy? Gut 2005;54:1343-4.
21. Haas S, Bindl L, Fischer HP. Autoimmune enteric leiomyositis: a rare cause of chronic intestinal pseudo-obstruction with specific morphological features. Hum Pathol 2005;36:576-80.