Leber's hereditary optic neuropathy associated with multiple sclerosis: Harding's syndrome

Practical Neurology

Volumn 8, Issue 2, 2008, Pages 118-121

  Parry Jones, Adrian R ^a   Mitchell, J D ^a   Gunarwardena, W J ^a   Shaunak, S ^a  

^a ROYAL PRESTON HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL DNA;

ADULT; ARTICLE; BRAIN; CASE REPORT; FEMALE; GENETICS; HUMAN; LEBER HEREDITARY OPTIC NEUROPATHY; MULTIPLE SCLEROSIS; MUTATION; PATHOLOGY; PATHOPHYSIOLOGY; SPINAL CORD; SYNDROME;

ADULT; BRAIN; DNA, MITOCHONDRIAL; FEMALE; HUMANS; MULTIPLE SCLEROSIS; MUTATION; OPTIC ATROPHY, HEREDITARY, LEBER; SPINAL CORD; SYNDROME;

EID: 41449096788     PISSN: 14747758     EISSN: None     Source Type: Journal    
DOI: 10.1136/jnnp.2007.139360     Document Type: Article

References (4)

1. Hardirg AE, Sweerey MG, Miller DH, et a. Occurrence of a multiple sclerosis-like illness in women who have a Leber's hereditary optic neuropathy mitochondrial DNA mutation. Brain 1992; 115:979-89.
2. Man PYW. Turnbull DM, Chinnery PF. Leber hereditary optic reuropathy. J Med Genet 2002;39:162-9.
3. Vanopdenbosch L, Dubois B, D'Hooghe MB, et al. Mitochondrial mutations of Leber's hereditary optic neuropathy: a risk factor for multiple sclerosis. J Neurol 2000;247:535-43.
4. Kovacs GG, Hoftberger R. Majtenyi K, et al. Neuropathology of white matter disease in Leber's hereditary optic neuropathy. Brain 2005;128:35-41.