Increased expression of LIGHT/TNFSF14 and its receptors in experimental and clinical heart failure

European Journal of Heart Failure

Volumn 10, Issue 4, 2008, Pages 352-359

  Dahl, Christen Peder ^a   Gullestad, Lars ^a   Fevang, Børre ^a   Holm, Are M ^a   Landrø, Linn ^a   Vinge, Leif Erik ^b   Fiane, Arnt E ^a   Sandberg, Wiggo J ^a   Otterdal, Kari ^a   Frøland, Stig S ^a   Damås, Jan Kristian ^a   Halvorsen, Bente ^a   Aukrust, Pål ^a   Øie, Erik ^a,b   Yndestad, Arne ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

Cytokines; Heart failure; Inflammation; Leukocytes; Tumour necrosis factor superfamily

Indexed keywords

CYTOKINE; CYTOKINE RECEPTOR; HERPESVIRUS ENTRY MEDIATOR; HVEM AND LYMPHOTOXIN ALPHA RECEPTOR; INTERLEUKIN 6; LYMPHOTOXIN LIKE EXHIBITS INDUCIBLE EXPRESSION AND COMPETES WITH HSV GLYCOPROTEIN D FOR HVEM A RECEPTOR EXPRESSED BY T LYMPHOCYTES PROTEIN; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; ENDOTHELIUM CELL; FEMALE; GENE EXPRESSION; HEART FAILURE; HEART INFARCTION; HEART LEFT VENTRICLE; HEART MUSCLE CELL; HUMAN; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; T LYMPHOCYTE; UPREGULATION;

ADULT; AGED; ANIMALS; ANTIGENS, CD3; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; FEMALE; HEART FAILURE; HEART VENTRICLES; HUMANS; INTERLEUKIN-6; LYMPHOTOXIN BETA RECEPTOR; MALE; MIDDLE AGED; MONOCYTES; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; RATS; RATS, WISTAR; RECEPTORS, TUMOR NECROSIS FACTOR, MEMBER 14; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14; UP-REGULATION;

EID: 41449096186     PISSN: 13889842     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejheart.2008.02.010     Document Type: Article

References (22)

1. Jessup M., and Brozena S. Heart failure. N Engl J Med 348 (2003) 2007-2018
2. Aukrust P., Gullestad L., Ueland T., Damås J.K., and Yndestad A. Inflammatory and anti-inflammatory cytokines in chronic heart failure: potential therapeutic implications. Ann Med 37 (2005) 74-85
3. Mann D.L. Inflammatory mediators and the failing heart: past, present, and the foreseeable future. Circ Res 91 (2002) 988-998
4. Yndestad A., Damås J.K., Øie E., Ueland T., Gullestad L., and Aukrust P. Systemic inflammation in heart failure-the whys and wherefores. Heart Fail Rev 11 (2006) 83-92
5. Nishigaki K., Minatoguchi S., Seishima M., et al. Plasma Fas ligand, an inducer of apoptosis, and plasma soluble Fas, an inhibitor of apoptosis, in patients with chronic congestive heart failure. J Am Coll Cardiol 29 (1997) 1214-1220
6. Ueland T., Aukrust P., Yndestad A., et al. Soluble CD40 ligand in acute and chronic heart failure. Eur Heart J 26 (2005) 1101-1107
7. Yndestad A., Damås J.K., Eiken H.G., et al. Increased gene expression of tumor necrosis factor superfamily ligands in peripheral blood mononuclear cells during chronic heart failure. Cardiovasc Res 54 (2002) 175-182
8. Ueland T., Yndestad A., Øie E., et al. Dysregulated osteoprotegerin/RANK ligand/RANK axis in clinical and experimental heart failure. Circulation 111 (2005) 2461-2468
9. Granger S.W., and Rickert S. LIGHT-HVEM signaling and the regulation of T cell-mediated immunity. Cytokine Growth Factor Rev 14 (2003) 289-296
10. Ware C.F. Network communications: lymphotoxins, LIGHT, and TNF. Annu Rev Immunol 23 (2005) 787-819
11. Wang J., Anders R.A., Wang Y., et al. The critical role of LIGHT in promoting intestinal inflammation and Crohn's disease. J Immunol 174 (2005) 8173-8182
12. Scholz H., Sandberg W., Damås J.K., et al. Enhanced plasma levels of LIGHT in unstable angina: possible pathogenic role in foam cell formation and thrombosis. Circulation 112 (2005) 2121-2129
13. Lee W.H., Kim S.H., Lee Y., et al. Tumor necrosis factor receptor superfamily 14 is involved in atherogenesis by inducing proinflammatory cytokines and matrix metalloproteinases. Arterioscler Thromb Vasc Biol 21 (2001) 2004-2010
14. Lo J.C., Wang Y., Tumanov A.V., et al. Lymphotoxin beta receptor-dependent control of lipid homeostasis. Science 316 (2007) 285-288
15. Øie E., Vinge L.E., Tønnessen T., et al. Transient, isopeptide-specific induction of myocardial endothelin-1 mRNA in congestive heart failure in rats. Am J Physiol Heart Circ Physiol 273 (1997) H1727-H1736
16. Otterdal K., Smith C., Øie E., et al. Platelet-derived LIGHT induces inflammatory responses in endothelial cells and monocytes. Blood 108 (2006) 928-935
17. Yndestad A., Holm A.M., Müller F., et al. Enhanced expression of inflammatory cytokines and activation markers in T-cells from patients with chronic heart failure. Cardiovasc Res 60 (2003) 141-146
18. Halvorsen B., Staff A.C., Ligaarden S., Prydz K., and Kolset S.O. Lithocholic acid and sulphated lithocholic acid differ in the ability to promote matrix metalloproteinase secretion in the human colon cancer cell line CaCo-2. Biochem J 349 (2000) 189-193
19. Waehre T., Damås J.K., Gullestad L., et al. Hydroxymethylglutaryl coenzyme a reductase inhibitors down-regulate chemokines and chemokine receptors in patients with coronary artery disease. J Am Coll Cardiol 41 (2003) 1460-1467
20. Hilfiker-Kleiner D., Landmesser U., and Drexler H. Molecular mechanisms in heart failure focus on cardiac hypertrophy, inflammation, angiogenesis, and apoptosis. J Am Coll Cardiol 48 (2006) A56-A66
21. Kwon B.S., Tan K.B., Ni J., et al. A newly identified member of the tumor necrosis factor receptor superfamily with a wide tissue distribution and involvement in lymphocyte activation. J Biol Chem 272 (1997) 14272-14276
22. Heo S.K., Ju S.A., Lee S.C., et al. LIGHT enhances the bactericidal activity of human monocytes and neutrophils via HVEM. J Leukoc Biol 79 (2006) 330-338