Kennedy's disease: A lower motor neuron model to identify upper motor neuron physiology in ALS

Clinical Neurophysiology

Volumn 119, Issue 5, 2008, Pages 971-972

  Eisen, Andrew ^a  

^a VANCOUVER GENERAL HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE;

AMYOTROPHIC LATERAL SCLEROSIS; AUTOPSY; EDITORIAL; EVOKED MUSCLE RESPONSE; GRAY MATTER; HISTOGRAM; HUMAN; KENNEDY DISEASE; MOTONEURON; MOTOR NEURON DISEASE; NERVE DEGENERATION; NEUROPATHIC JOINT DISEASE; NEUROPATHOLOGY; NEUROPHYSIOLOGY; NONHUMAN; POLIOMYELITIS; PRIORITY JOURNAL; TRANSCRANIAL MAGNETIC STIMULATION;

AMYOTROPHIC LATERAL SCLEROSIS; ANTERIOR HORN CELLS; CEREBRAL CORTEX; HUMANS; MOTOR NEURONS; MUSCULAR ATROPHY, SPINAL; NERVE DEGENERATION;

EID: 41449085781     PISSN: 13882457     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinph.2008.01.012     Document Type: Editorial

References (12)

1. Browne S.E., Yang L., DiMauro J.P., Fuller S.W., Licata S.C., and Beal M.F. Bioenergetic abnormalities in discrete cerebral motor pathways presage spinal cord pathology in the G93A SOD1 mouse model of ALS. Neurobiol Dis 22 (2006) 599-610
2. Charcot J.J.A. Deux cas d'astrophie musculaire progressive avec lesions de la substance grise et des faisceaux antero lateraux de la moelle epiniere. Arch Physiol Neurol Pathol 2 (1869) 744-754
3. Eisen A., and Weber M. The motor cortex and amyotrophic lateral sclerosis. Muscle Nerve 24 (2001) 564-573
4. Karitzky J., Block W., Mellies J.K., Traber F., Sperfeld A., Schild H.H., et al. Proton magnetic resonance spectroscopy in Kennedy syndrome. Arch Neurol 56 (1999) 1465-1471
5. Kennedy W.R., Alter M., and Sung J.H. Progressive proximal spinal and bulbar muscular atrophy of late onset. A sex-linked recessive trait. Neurology 18 (1968) 671-680
6. Lule D, Ludolph AC, Ludolph AG. Neurodevelopmental and neurodegenerative diseases - is there a pathophysiological link? Attention-deficit/hyperactivity disorder and amyotrophic lateral sclerosis as examples. Med Hypothesis, in press.
7. Oliveri M., Brighina V., La Bua D., Buffa A., Aloisio A., and Fierro B. Reorganization in cortical motor area in prior polio patients. Clin Neurophysiol 110 (1999) 806-812
8. Pachatz C., Terracciano C., Desiato M.T., Orlacchio A., Mori F., Rocchi C., et al. Upper motor neuron involvement in X-linked recessive bulbospinal muscular atrophy. Clin Neurophysiol 118 (2007) 262-268
9. Shaw P.J., Thagesen H., Tomkins J., Slade Y., Usher P., Jackson A., et al. Kennedy's disease: unusual molecular pathologic and clinical features. Neurology 51 (1998) 252-255
10. Vucic S., and Kiernan M.C. Novel threshold tracking techniques suggest that cortical hyperexcitability is an early feature of motor neuron disease. Brain 129 (2006) 2436-2446
11. Vucic O., and Kiernan M.C. Cortical excitability testing distinguishes Kennedy's disease from amyotrophic lateral sclerosis. Clin Neurophysiol 119 (2008) 1088-1096
12. Weber M., and Eisen A. Assessment of upper and lower motor neurons in Kennedy's disease: implications for corticomotoneuronal PSTH studies. Muscle Nerve 22 (1999) 299-306