Poly(ADP-ribose) glycohydrolase as a target for neuroprotective intervention: Assessment of currently available pharmacological tools

European Journal of Pharmacology

Volumn 497, Issue 1, 2004, Pages 7-16

  Falsig, Jeppe ^a,b   Christiansen, Søren Hofman ^a   Feuerhahn, Sascha ^c   Bürkle, Alexander ^c   Oei, Shiao Li ^d   Keil, Claudia ^d   Leist, Marcel ^a  

^a H LUNDBECK A S   (Denmark)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c UNIVERSITY OF KONSTANZ   (Germany)

^d FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Astrocyte; Cell death; Gallotannin; GPI 16552; PARG; PARP

Indexed keywords

DNA; GLYCOSIDASE; GPI 16552; METHYLNITRONITROSOGUANIDINE; N BIS(3 PHENYLPROPYL) 9 OXOFLUORENE 2,7 DIAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; POLY(ADP RIBOSE)GLYCOHYDROLASE; SCAVENGER; TANNIN; TANNIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASSAY; ASTROCYTE; CELL DEATH; CELL PROTECTION; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DRUG ACTIVITY; DRUG EFFECT; DRUG SPECIFICITY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; INHIBITION KINETICS; MODEL; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN TARGETING; VALIDATION PROCESS;

ANIMALS; ANIMALS, NEWBORN; ANTIOXIDANTS; ASTROCYTES; BLOTTING, WESTERN; CATALYTIC DOMAIN; CELL DEATH; CELLS, CULTURED; DNA DAMAGE; FLUORENES; FREE RADICAL SCAVENGERS; GLYCOSIDE HYDROLASES; HUMANS; HYDROLYZABLE TANNINS; METHYLNITRONITROSOGUANIDINE; MICE; MICE, INBRED C57BL; NEUROPROTECTIVE AGENTS; NITRIC OXIDE; POLY(ADP-RIBOSE) POLYMERASES;

EID: 4143154152     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.06.042     Document Type: Article

References (34)

1. R. Alvarez-Gonzalez, and F.R. Althaus Poly(ADP-ribose) catabolism in mammalian cells exposed to DNA-damaging agents Mutat. Res. 218 1989 67 74
2. K. Aoki, K. Nishimura, H. Abe, H. Maruta, H. Sakagami, T. Hatano, T. Okuda, T. Yoshida, Y.J. Tsai, and F. Uchiumi Novel inhibitors of poly(ADP-ribose) glycohydrolase Biochim. Biophys. Acta 1158 1993 251 256
3. M. Banasik, H. Komura, M. Shimoyama, and K. Ueda Specific inhibitors of poly(ADP-ribose) synthetase and mono(ADP-ribosyl)transferase J. Biol. Chem. 267 1992 1569 1575
4. A. Bürkle, G. Chen, J.H. Küpper, K. Grube, and W.J. Zeller Increased poly(ADP-ribosyl)ation in intact cells by cisplatin treatment Carcinogenesis 14 4 1993 Apr 559 561
5. I. Chantret, A. Barbat, E. Dussaulx, M.G. Brattain, and A. Zweibaum Epithelial polarity, villin expression, and enterocytic differentiation of cultured human colon carcinoma cells: a survey of twenty cell lines Cancer Res. 48 1988 1936 1942
6. A. Chiarugi Poly(ADP-ribose) polymerase: killer or conspirator? The 'suicide hypothesis' revisited Trends Pharmacol. Sci. 23 2002 122 129
7. M. Chiesi, and R. Schwaller Inhibition of constitutive endothelial NO-synthase activity by tannin and quercetin Biochem. Pharmacol. 49 1995 495 501
8. L. Davidovic, M. Vodenicharov, E.B. Affar, and G.G. Poirier Importance of poly(ADP-ribose) glycohydrolase in the control of poly(ADP-ribose) metabolism Exp. Cell Res. 268 2001 7 13
9. G. de Murcia, A. Huletsky, and G.G. Poirier Modulation of chromatin structure by poly(ADP-ribosyl)ation Biochem. Cell. Biol. 66 1988 626 635
10. J. Falsig, M. Latta, and M. Leist Defined inflammatory states in astrocyte cultures: correlation with susceptibility towards CD95-driven apoptosis J. Neurochem. 88 2004 181 193
11. J. Griesenbeck, S.L. Oei, P. Mayer-Kuckuk, M. Ziegler, G. Buchlow, and M. Schweiger Proteinâ€"protein interaction of the human poly(ADP-ribosyl)transferase depends on the functional state of the enzyme Biochemistry 36 1997 7297 7304
12. H.C. Ha, L.D. Hester, and S.H. Snyder Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia Proc. Natl. Acad. Sci. U. S. A. 99 2002 3270 3275
13. S. Hanai, M. Kanai, S. Ohashi, K. Okamoto, M. Yamada, H. Takahashi, and M. Miwa Loss of poly(ADP-ribose) glycohydrolase causes progressive neurodegeneration in Drosophila melanogaster Proc. Natl. Acad. Sci. U. S. A. 101 2004 82 86
14. J.J. Hwang, S.Y. Choi, and J.Y. Koh The role of NADPH oxidase, neuronal nitric oxide synthase and poly(ADP ribose) polymerase in oxidative neuronal death induced in cortical cultures by brain-derived neurotrophic factor and neurotrophin-4/5 J. Neurochem. 82 2002 894 902
15. M. Kaneko, Y. Saito, H. Saito, T. Matsumoto, Y. Matsuda, J.L. Vaught, C.A. Dionne, T.S. Angeles, M.A. Glicksman, N.T. Neff, D.P. Rotella, J.C. Kauer, J.P. Mallamo, R.L. Hudkins, and C. Murakata Neurotrophic 3,9-bis[(alkylthio) methyl]-and-bis(alkoxymethyl)-K-252a derivatives J. Med. Chem. 40 1997 1863 1869
16. H. Kawamitsu, H. Hoshino, H. Okada, M. Miwa, H. Momoi, and T. Sugimura Monoclonal antibodies to poly(adenosine diphosphate ribose) recognize different structures Biochemistry 23 16 1984 Jul. 31 3771 3777
17. C. Keil, E. Petermann, and S.L. Oei Tannins elevate the level of poly(ADP-ribose) in HeLa cell extracts Arch. Biochem. Biophys. 425 2004 115 121
18. Y.H. Kim, and J.Y. Koh The role of NADPH oxidase and neuronal nitric oxide synthase in zinc-induced poly(ADP-ribose) polymerase activation and cell death in cortical culture Exp. Neurol. 177 2002 407 418
19. M. Labieniec, T. Gabryelak, and G. Falcioni Antioxidant and pro-oxidant effects of tannins in digestive cells of the freshwater mussel Unio tumidus Mutat. Res. 539 2003 19 28
20. J. Li, D.V. Ferraris, P.W. Kletzly, W. Li, E.Y. Wang, A.D. Xing, W. Xu, and J. Zhang Symmetrically disubstituted aromatic compounds and pharmaceutical compositions for inhibiting poly(ADP-ribose) glycohydrolase and methods for their use World Intellect. Prop. Org. 2002
21. G.K. Lopes, H.M. Schulman, and M. Hermes-Lima Polyphenol tannic acid inhibits hydroxyl radical formation from Fenton reaction by complexing ferrous ions Biochim. Biophys. Acta 1472 1999 142 152
22. X.C. Lu, E. Massuda, Q. Lin, W. Li, J.H. Li, and J. Zhang Post-treatment with a novel PARG inhibitor reduces infarct in cerebral ischemia in the rat Brain Res. 978 2003 99 103
23. M. Masutani, H. Nakagama, and T. Sugimura Poly(ADP-ribose) and carcinogenesis Genes, Chromosomes Cancer 38 2003 339 348
24. A.A. Pieper, A. Verma, J. Zhang, and S.H. Snyder Poly(ADP-ribose) polymerase, nitric oxide and cell death Trends Pharmacol. Sci. 20 1999 171 181
25. M.R. Purnell, and W.J. Whish Novel inhibitors of poly(ADP-ribose) synthetase Biochem. J. 185 1980 775 777
26. M.S. Satoh, G.G. Poirier, and T. Lindahl Dual function for poly(ADP-ribose) synthesis in response to DNA strand breakage Biochemistry 33 1994 7099 7106
27. G.M. Shah, D. Poirier, S. Desnoyers, S. Saint-Martin, J.C. Hoflack, P. Rong, M. ApSimon, J.B. Kirkland, and G.G. Poirier Complete inhibition of poly(ADP-ribose) polymerase activity prevents the recovery of C3H10T1/2 cells from oxidative stress Biochim. Biophys. Acta 1312 1996 1 7
28. C. Szabo, and V.L. Dawson Role of poly(ADP-ribose) synthetase in inflammation and ischaemiaâ€"reperfusion Trends Pharmacol. Sci. 19 1998 287 298
29. Y.J. Tsai, T. Aoki, H. Maruta, H. Abe, H. Sakagami, T. Hatano, T. Okuda, and S. Tanuma Mouse mammary tumor virus gene expression is suppressed by oligomeric ellagitannins, novel inhibitors of poly(ADP-ribose) glycohydrolase J. Biol. Chem. 267 1992 14436 14442
30. D.E. Weinstein Isolation and Purification of Primary Rodent Astrocytes. Current Protocols in Neuroscience, 3.5.1â€"3.5.9 1997 John Wiley and Sons Hoboken, NY, USA
31. W. Ying, and R.A. Swanson The poly(ADP-ribose) glycohydrolase inhibitor gallotannin blocks oxidative astrocyte death NeuroReport 11 2000 1385 1388
32. W. Ying, M.B. Sevigny, Y. Chen, and R.A. Swanson Poly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal death Proc. Natl. Acad. Sci. U. S. A. 98 2001 12227 12232
33. T. Yokozawa, C.P. Chen, E. Dong, T. Tanaka, G.I. Nonaka, and I. Nishioka Study on the inhibitory effect of tannins and flavonoids against the 1,1-diphenyl-2 picrylhydrazyl radical Biochem. Pharmacol. 56 1998 213 222
34. P. Zahradka, and K. Ebisuzaki A shuttle mechanism for DNA-protein interactions. The regulation of poly(ADP-ribose) polymerase Eur. J. Biochem. 127 1982 579 585