The very-long-chain fatty acid synthase is inhibited by chloroacetamides

Zeitschrift fur Naturforschung - Section C Journal of Biosciences

Volumn 59, Issue 7-8, 2004, Pages 549-553

  Götz, Thomas ^a   Böger, Peter ^a  

^a UNIVERSITY OF KONSTANZ   (Germany)

Author keywords

Fatty Acid Elongation; Recombinant VLCFA Synthase; Tight Inhibitor Binding

Indexed keywords

EID: 4143140858     PISSN: 09395075     EISSN: None     Source Type: Journal    
DOI: 10.1515/znc-2004-7-818     Document Type: Article

References (11)

1. Böger P. (2003), Mode of action of chloroacetamides and functionally related compounds. J. Pestic. Sci. (Japan) 28, 324-329.
2. Böger P., Matthes B., and Schmalfuß J. (2000), Towards the primary target of chloroacetamides: new findings pave the way. Pest Manag. Sci. 56, 497-508.
3. Couderchet M., Brozio B., and Böger P. (1994), Effect and metabolism of the chloroacetamide herbicide metazachlor: comparison of plant cell suspension cultures and seedlings. J. Pestic. Sci. 19, 127-135.
4. Couderchet M., Bocion P. F., Chollet R., Seckinger K., and Böger P. (1997), Biological activity of two stereoisomers of the N-thienyl chloroacetamide herbicide dimethenamid. Pestic. Sci. 50, 221-227.
5. Fuerst E. P., Lamoureux G. L., and Ahrens W. H. (1991), Mode of action of the dichloroacetamide antidote BAS 145-138 in corn. I. Growth responses and fate of metazachlor. Pestic. Biochem. Physiol. 19, 127-135.
6. Ghanevati M. and Jaworski J. G. (2002), Engineering and mechanistic studies of the Arabidopsis FAE1 β-ketoacyl synthase FAE1 KCS. Eur. J. Biochem. 269, 3531-3539.
7. Matthes B. and Böger P. (2002), Chloroacetamides affect the plasma membrane. Z. Naturforsch. 57c, 843-852.
8. Matthes B., Schmalfuß J., and Böger P. (1998), Chloroacetamide mode of action, II: Inhibition of very-long-chain fatty acid synthesis in higher plants. Z. Naturforsch. 53c, 1004-1011.
9. Millar A. A. and Kunst L. (1997), Very-long-chain fatty acid biosynthesis is controlled through the expression and specificity of the condensing enzyme. Plant J. 12, 121-131.
10. Schmalfuß J., Matthes B., Knuth K., and Böger P. (2000), Inhibition of acyl-CoA elongation by chloroacetamide herbicides in microsomes from leek seedlings. Pestic. Biochem. Physiol. 67, 25-35.
11. Tomlin C. D. S. (ed.) (2000), The Pesticide Manual, 12th edition. British Crop Protection Council, Farnham, Surrey, UK.