-
1
-
-
0002752364
-
Contribution to our knowledge of ketenes. First paper. Diphenylketene
-
Staudinger, H. Contribution to our Knowledge of Ketenes. First Paper. Diphenylketene. Liebigs Ann. Chem. 1908, 356, 51-123.
-
(1908)
Liebigs Ann. Chem.
, vol.356
, pp. 51-123
-
-
Staudinger, H.1
-
2
-
-
0004030277
-
-
Morin, R. B. Gorman, M., Eds.; Academic Press: New York
-
Chemistry and Biology of β-Lactam Antibiotics; Morin, R. B. Gorman, M., Eds.; Academic Press: New York, 1982; Vols. 1-3.
-
(1982)
Chemistry and Biology of β-Lactam Antibiotics
, vol.1-3
-
-
-
3
-
-
0027326783
-
Penicillins. A current review of their clinical pharmacology and therapeutic use
-
For a review on the use of penicillin, see: Nathwani, D.; Wood, M. J. Penicillins. A Current Review of their Clinical Pharmacology and Therapeutic Use. Drugs 1993, 45, 866-894.
-
(1993)
Drugs
, vol.45
, pp. 866-894
-
-
Nathwani, D.1
Wood, M.J.2
-
4
-
-
0003737979
-
-
Sutcliffe, J., Georgopapadakou, N. H., Eds.; Chapman and Hall: New York
-
Nehaus, F. C.; Georgapadaku, N. H. In Emerging Targets in Antibacterial and Antifungal Chemotherapy; Sutcliffe, J., Georgopapadakou, N. H., Eds.; Chapman and Hall: New York, 1992.
-
(1992)
Emerging Targets in Antibacterial and Antifungal Chemotherapy
-
-
Nehaus, F.C.1
Georgapadaku, N.H.2
-
6
-
-
17344377814
-
Potent beta-lactam inhibitors of human cytomegalovirus protease
-
(b) Yoakim, C.; Ogilvie, W.; Cameron, D.; Chabot, C.; Grande-Matre, C.; Guse, I.; Hache, B.; Naud, J.; Kawai, S.; O'Meara, J.; Plante, R.; Deziel, R. Potent Beta-Lactam Inhibitors of Human Cytomegalovirus Protease. Antiviral Chem. Chemother. 1998, 9, 379-387.
-
(1998)
Antiviral Chem. Chemother.
, vol.9
, pp. 379-387
-
-
Yoakim, C.1
Ogilvie, W.2
Cameron, D.3
Chabot, C.4
Grande-Matre, C.5
Guse, I.6
Hache, B.7
Naud, J.8
Kawai, S.9
O'Meara, J.10
Plante, R.11
Deziel, R.12
-
8
-
-
0033594922
-
Mechanistic insights into the inhibition of serine proteases by monocyclic lactams
-
Wilmouth, R. C.; Kassamally, S.; Westwood, N. J.; Sheppard, R. J.; Claridge, T. D.; Alpin, R. T.; Wright, P. A.; Pritchard, G. J.; Schofield, C. J. Mechanistic Insights into the Inhibition of Serine Proteases by Monocyclic Lactams. Biochemistry 1999, 38, 7989-7998.
-
(1999)
Biochemistry
, vol.38
, pp. 7989-7998
-
-
Wilmouth, R.C.1
Kassamally, S.2
Westwood, N.J.3
Sheppard, R.J.4
Claridge, T.D.5
Alpin, R.T.6
Wright, P.A.7
Pritchard, G.J.8
Schofield, C.J.9
-
9
-
-
0027535432
-
2 dipeptide replacements
-
2 Dipeptide Replacements. Bioorg Med. Chem. Lett. 1993, 3, 773-778.
-
(1993)
Bioorg Med. Chem. Lett.
, vol.3
, pp. 773-778
-
-
Skiles, J.W.1
Sorcek, R.2
Jacober, S.3
Miao, C.4
Mui, P.W.5
McNeil, D.6
Rosenthal, A.S.7
-
10
-
-
0032783662
-
Synthesis and antiviral activity of monobactams inhibiting the human cytomegalovirus protease
-
Ogilvie, W. W.; Yoakim, C.; Hache, F. D. B.; Lagace, L.; Naud, J.; O'Meara, J. A.; Deziel, R. Synthesis and Antiviral Activity of Monobactams Inhibiting the Human Cytomegalovirus Protease. Bioorg. Med. Chem. 1999, 7, 1521-1531.
-
(1999)
Bioorg. Med. Chem.
, vol.7
, pp. 1521-1531
-
-
Ogilvie, W.W.1
Yoakim, C.2
Hache, F.D.B.3
Lagace, L.4
Naud, J.5
O'Meara, J.A.6
Deziel, R.7
-
11
-
-
0029098953
-
Azetidin-2-one derivatives as inhibitors of thrombin
-
Han, W. T.; Trehan, A. K.; Wright, J. J. K.; Federici, M. E.; Seiler, S. M.; Meanwell, N. A. Azetidin-2-one Derivatives as Inhibitors of Thrombin. Bioorg. Med. Chem. 1995, 3, 1123-1143.
-
(1995)
Bioorg. Med. Chem.
, vol.3
, pp. 1123-1143
-
-
Han, W.T.1
Trehan, A.K.2
Wright, J.J.K.3
Federici, M.E.4
Seiler, S.M.5
Meanwell, N.A.6
-
12
-
-
0030860598
-
Design and synthesis of novel monocyclic β-lactam inhibitors of prostate specific antigen
-
Addington, R. M.; Baldwin, J. E.; Chen, B.; Cooper, S. L.; McCoull, W.; Pritchard, G. J.; Howe, T. J. Design and Synthesis of Novel Monocyclic β-Lactam Inhibitors of Prostate Specific Antigen. Bioorg. Med. Chem. Lett. 1997, 7, 1689-1694.
-
(1997)
Bioorg. Med. Chem. Lett.
, vol.7
, pp. 1689-1694
-
-
Addington, R.M.1
Baldwin, J.E.2
Chen, B.3
Cooper, S.L.4
McCoull, W.5
Pritchard, G.J.6
Howe, T.J.7
-
13
-
-
0029147178
-
Synthesis and β-lactamase inhibitory evaluation of novel 6α-halo-2β-chloramethyl-2α-methylpenam-3α-carboxylic acids and their sulfones and 6α-halo-2β-mercaptobeozothiazolyl- methyl-2α-methylpenam-3α-carboxylic acids
-
Danelon, G. O.; Mata, E. G.; Mascaretti, O. A.; Girardini, J.; Marro, M.; Roveri, O. A. Synthesis and β-Lactamase Inhibitory Evaluation of Novel 6α-Halo-2β-chloramethyl-2α-methylpenam-3α-carboxylic Acids and their sulfones and 6α-Halo-2β-mercaptobeozothiazolyl- methyl-2α-methylpenam-3α-carboxylic Acids. Biorg. Med. Chem. Lett. 1995, 5, 2037-2040.
-
(1995)
Biorg. Med. Chem. Lett.
, vol.5
, pp. 2037-2040
-
-
Danelon, G.O.1
Mata, E.G.2
Mascaretti, O.A.3
Girardini, J.4
Marro, M.5
Roveri, O.A.6
-
14
-
-
4143142813
-
-
Eur. Pat. Appl., 1989, 31pp
-
Tsuruoka, T.; Nakabayahi, S.; Fukuyasu, H.; Ishii, Y.; Tsuruoka, T.; Yamamoto, H.; Inouye, S.; Kondo, S. Eur. Pat. Appl., 1989, 31pp.
-
-
-
Tsuruoka, T.1
Nakabayahi, S.2
Fukuyasu, H.3
Ishii, Y.4
Tsuruoka, T.5
Yamamoto, H.6
Inouye, S.7
Kondo, S.8
-
15
-
-
0029975253
-
-
Dugar, S.; Yumibe, N.; Clader, J.; W.; Vizziano, M.; Huie, K.; van Heek, M.; Compton, D. S.; Davis, H. R., Jr. Bioorg. Med. Chem. Lett. 1996, 6, 1271-1274.
-
(1996)
Bioorg. Med. Chem. Lett.
, vol.6
, pp. 1271-1274
-
-
Dugar, S.1
Yumibe, N.2
Clader, J.3
Vizziano, M.4
Huie, K.5
Van Heek, M.6
Compton, D.S.7
Davis Jr., H.R.8
-
16
-
-
0004030275
-
-
Page, M. I., Ed.; Chapman Hall: New York
-
The Chemistry of β-Lactams; Page, M. I., Ed.; Chapman Hall: New York, 1992.
-
(1992)
The Chemistry of β-Lactams
-
-
-
17
-
-
0032707721
-
Asymmetric synthesis of β-lactams by staudinger ketene-imine cycloaddition reaction
-
Palomo, C.; Aizpurua, J. M.; Ganboa, I.; Oiarbide, M. Asymmetric Synthesis of β-Lactams by Staudinger Ketene-Imine Cycloaddition Reaction. Eur. J. Org. Chem. 1999, 3223-3235.
-
(1999)
Eur. J. Org. Chem.
, pp. 3223-3235
-
-
Palomo, C.1
Aizpurua, J.M.2
Ganboa, I.3
Oiarbide, M.4
-
18
-
-
33947443800
-
The reformatsky reaction with benzalaniline
-
(a) Gilman, H.; Speeter, M. The Reformatsky Reaction with Benzalaniline. J. Am. Chem. Soc. 1943, 65, 2255-2256,
-
(1943)
J. Am. Chem. Soc.
, vol.65
, pp. 2255-2256
-
-
Gilman, H.1
Speeter, M.2
-
19
-
-
33845183324
-
The ester enolate-imine condensation route to β-lactams
-
(b) Hart, D. J.; Ha, D.-C. The Ester Enolate-Imine Condensation Route to β-Lactams. Chem. Rev. 1989, 89, 1447-1465.
-
(1989)
Chem. Rev.
, vol.89
, pp. 1447-1465
-
-
Hart, D.J.1
Ha, D.-C.2
-
20
-
-
0034006463
-
The S-thioester enolate/imine condensation: A shortcut to β-lactams
-
(c) Benaglia, M.; Cinquini, M.; Cozzi, F. The S-Thioester Enolate/Imine Condensation: A Shortcut to β-Lactams. Eur. J. Org. Chem. 2000, 563-572.
-
(2000)
Eur. J. Org. Chem.
, pp. 563-572
-
-
Benaglia, M.1
Cinquini, M.2
Cozzi, F.3
-
21
-
-
0034607972
-
Enantioselective photocyclization of amides to β-lactam derivatives in inclusion crystals with an optically active host
-
Toda, F.; Miyamoto, H.; Inoue, M.; Yasaka, S.; Matijasic, I. Enantioselective Photocyclization of Amides to β-Lactam Derivatives in Inclusion Crystals with an Optically Active Host. J. Org. Chem. 2000, 65, 2728-2732.
-
(2000)
J. Org. Chem.
, vol.65
, pp. 2728-2732
-
-
Toda, F.1
Miyamoto, H.2
Inoue, M.3
Yasaka, S.4
Matijasic, I.5
-
22
-
-
0030026894
-
Asymmetric radical cyclization leading to β-lactams: Stereoselective synthesis of chiral key intermediates for carbapenem antibiotics PS-5 and thienamycin
-
Ishibashi, H.; Kameoka, C.; Kodama, K.; Ikeda, M. Asymmetric Radical Cyclization Leading to β-Lactams: Stereoselective Synthesis of Chiral Key Intermediates for Carbapenem Antibiotics PS-5 and Thienamycin. Tetrahedron 1996, 52, 489-502.
-
(1996)
Tetrahedron
, vol.52
, pp. 489-502
-
-
Ishibashi, H.1
Kameoka, C.2
Kodama, K.3
Ikeda, M.4
-
23
-
-
0021875983
-
The asymmetric synthesis of β-lactam antibiotics I. application of chiral oxazolidones in the staudinger reaction
-
(a) Evans, D. A.; Sjogren, E. B. The Asymmetric Synthesis of β-Lactam Antibiotics I. Application of Chiral Oxazolidones in the Staudinger Reaction. Tetrahedron Lett. 1985, 26, 3783-3786.
-
(1985)
Tetrahedron Lett.
, vol.26
, pp. 3783-3786
-
-
Evans, D.A.1
Sjogren, E.B.2
-
24
-
-
0026636760
-
Stereoregulated synthesis of β-lactams from schiff bases derived from threonine esters
-
(b) Bose, A. K.; Manhas, M. S.; van der Veen, J. M.; Bari, S. S.; Wagle, D. R. Stereoregulated Synthesis of β-lactams from Schiff Bases Derived from Threonine Esters. Tetrahedron 1992, 48, 4831-4844.
-
(1992)
Tetrahedron
, vol.48
, pp. 4831-4844
-
-
Bose, A.K.1
Manhas, M.S.2
Van Der Veen, J.M.3
Bari, S.S.4
Wagle, D.R.5
-
26
-
-
0000796770
-
Construction of β-lactams by highly selective intramolecular carbon-hydrogen insertion from rhodium(II) carboxylate catalyzed reactions of diazoacetamides
-
(a) Doyle, M. P.; Shanklin, M. S.; Oon, S.-M.; Pho, H. Q.; van der Heide, F. R.; Veal, W. R. Construction of β-lactams by Highly Selective Intramolecular Carbon-Hydrogen Insertion from Rhodium(II) Carboxylate Catalyzed Reactions of Diazoacetamides. J. Org. Chem. 1988, 53, 3384-3386.
-
(1988)
J. Org. Chem.
, vol.53
, pp. 3384-3386
-
-
Doyle, M.P.1
Shanklin, M.S.2
Oon, S.-M.3
Pho, H.Q.4
Van Der Heide, F.R.5
Veal, W.R.6
-
27
-
-
0001595444
-
Conformational and electronic preferences in rhodium-(II) carboxylate and rhodium(II) carboxamide catalyzed carbon-hydrogen insertion reactions of N,N-disubstituted diazoacetoacetamides
-
(b) Doyle, M. P.; Taunton, J.; Pho, H. Q. Conformational and Electronic Preferences in Rhodium-(II) Carboxylate and Rhodium(II) Carboxamide Catalyzed Carbon-Hydrogen Insertion Reactions of N,N-Disubstituted Diazoacetoacetamides. Tetrahedron Lett. 1989, 30, 5397-5400.
-
(1989)
Tetrahedron Lett.
, vol.30
, pp. 5397-5400
-
-
Doyle, M.P.1
Taunton, J.2
Pho, H.Q.3
-
28
-
-
33751500380
-
Synthesis of nitrogen-containing polycycles via rhodium(II)-induced cyclization-cycloaddition and insertion reactions of N-(diazoacetoacetyl)amides. Conformational control of reaction selectivity
-
(c) Doyle, M. P.; Pieters, R. J.; Taunton, J.; Pho, H.; Padwa, A.; Hertzog, D. L.; Precedo, L. Synthesis of Nitrogen-Containing Polycycles Via Rhodium(II)-Induced Cyclization-Cycloaddition and Insertion Reactions of N-(Diazoacetoacetyl)amides. Conformational Control of Reaction Selectivity. J. Org. Chem. 1991, 56, 820-829.
-
(1991)
J. Org. Chem.
, vol.56
, pp. 820-829
-
-
Doyle, M.P.1
Pieters, R.J.2
Taunton, J.3
Pho, H.4
Padwa, A.5
Hertzog, D.L.6
Precedo, L.7
-
30
-
-
0019495121
-
A novel synthesis of β-lactams
-
(a) Alper, H.; Perera, C. P.; Ahmed, F. R. A Novel Synthesis of β-Lactams. J. Am. Chem. Sac 1981, 103, 1289-1291.
-
(1981)
J. Am. Chem. Soc.
, vol.103
, pp. 1289-1291
-
-
Alper, H.1
Perera, C.P.2
Ahmed, F.R.3
-
31
-
-
0024546617
-
Enantiospecific and stereospecific rhodium-(I)-catalyzed carbonylation and ring expansion of aziridines. Asymmetric synthesis of β-lactams and the kinetic resolution of aziridines
-
(b) Calet, S.; Urso, F.; Alper, H. Enantiospecific and Stereospecific Rhodium-(I)-Catalyzed Carbonylation and Ring Expansion of Aziridines. Asymmetric Synthesis of β-Lactams and the Kinetic Resolution of Aziridines. J. Am. Chem. Soc. 1989, 111, 931-934.
-
(1989)
J. Am. Chem. Soc.
, vol.111
, pp. 931-934
-
-
Calet, S.1
Urso, F.2
Alper, H.3
-
32
-
-
0033593414
-
Carbonylation of silylated hydroxymethyl aziridines to β-lactams
-
(c) Davoli, P.; Moretti, I.; Prati, F.; Alper, H. Carbonylation of Silylated Hydroxymethyl Aziridines to β-Lactams. J. Org. Chem. 1999, 64, 518-521.
-
(1999)
J. Org. Chem.
, vol.64
, pp. 518-521
-
-
Davoli, P.1
Moretti, I.2
Prati, F.3
Alper, H.4
-
33
-
-
0030928524
-
A ternary complex reagent for an asymmetric reaction of lithium ester enolates with imines
-
(a) Fujieda, H.; Kanai, M.; Kambara, T.; Iida, A.; Tomioka, K. A Ternary Complex Reagent for an Asymmetric Reaction of Lithium Ester Enolates with Imines. J. Am. Chem. Soc. 1997, 119, 2060-2061.
-
(1997)
J. Am. Chem. Soc.
, vol.119
, pp. 2060-2061
-
-
Fujieda, H.1
Kanai, M.2
Kambara, T.3
Iida, A.4
Tomioka, K.5
-
34
-
-
0033591004
-
Catalytic asymmetric reaction of lithium ester enolates with imines
-
(b) Tomioka, K.; Fujieda, H.; Hayashi, S.; Hussein, M. A.; Kambara, T.; Nomura, Y.; Kanai, M.; Koga, K. Catalytic Asymmetric Reaction of Lithium Ester Enolates with Imines. Chem. Commun. 1999, 715-716.
-
(1999)
Chem. Commun.
, pp. 715-716
-
-
Tomioka, K.1
Fujieda, H.2
Hayashi, S.3
Hussein, M.A.4
Kambara, T.5
Nomura, Y.6
Kanai, M.7
Koga, K.8
-
35
-
-
0029089453
-
Copper-catalyzed reaction of terminal alkynes with nitrones. Selective synthesis of 1-aza-1-buten-3-yne and 2-azetidinone derivatives
-
Miura, M.; Enna, M.; Okuro, K.; Nomura, M. Copper-Catalyzed Reaction of Terminal Alkynes with Nitrones. Selective Synthesis of 1-Aza-1-buten-3-yne and 2-Azetidinone Derivatives. J. Org. Chem. 1995, 60, 4999-5004.
-
(1995)
J. Org. Chem.
, vol.60
, pp. 4999-5004
-
-
Miura, M.1
Enna, M.2
Okuro, K.3
Nomura, M.4
-
36
-
-
0037181062
-
Enantioselective staudinger synthesis of β-lactams catalyzed by a planar-chiral nucleophile
-
Hodous, B. L.; Fu, G. C. Enantioselective Staudinger Synthesis of β-Lactams Catalyzed by a Planar-Chiral Nucleophile. J. Am. Chem. Soc. 2002, 124, 1578-1579.
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 1578-1579
-
-
Hodous, B.L.1
Fu, G.C.2
-
37
-
-
0036570894
-
Cu(I)/bis(azaferrocene)-catalyzed enantioselective synthesis of β-lactams via couplings of alkynes with nitrones
-
(a) Lo, M. M.-C.; Fu, G. C. Cu(I)/Bis(azaferrocene)-Catalyzed Enantioselective Synthesis of β-Lactams via Couplings of Alkynes with Nitrones. J. Am. Chem., Soc. 2002, 124, 4572-4573.
-
(2002)
J. Am. Chem., Soc.
, vol.124
, pp. 4572-4573
-
-
Lo, M.M.-C.1
Fu, G.C.2
-
38
-
-
0141788715
-
Catalytic enantioselective synthesis of β-lactams: Intramolecular kinugasa reactions and interception of an intermediate in the reaction cascade
-
(b) Shintani, R.; Fu, G. C. Catalytic Enantioselective Synthesis of β-Lactams: Intramolecular Kinugasa Reactions and Interception of an Intermediate in the Reaction Cascade. Angew. Chem., Int. Ed. 2003, 42, 4082-4085.
-
(2003)
Angew. Chem., Int. Ed.
, vol.42
, pp. 4082-4085
-
-
Shintani, R.1
Fu, G.C.2
-
39
-
-
0001388951
-
Stereochemical studies of thermal intermolecular and intramolecular N-sulfonylimine ene reactions
-
We chose N-tosyl imino esters for our initial experiments. These were first popularized in work by: Tschaen, D. H.; Turos, E.; Weinreb, S. M. Stereochemical Studies of Thermal Intermolecular and Intramolecular N-Sulfonylimine Ene Reactions. J. Org. Chem. 1984, 49, 5058-5064.
-
(1984)
J. Org. Chem.
, vol.49
, pp. 5058-5064
-
-
Tschaen, D.H.1
Turos, E.2
Weinreb, S.M.3
-
40
-
-
0037244819
-
α-imino esters: Versatile substrates for the catalytic, asymmetric synthesis of α- and β-amino acids and β-lactams
-
Taggi, A. E.; Hafez, A. M.; Lectka, T. α-Imino Esters: Versatile Substrates for the Catalytic, Asymmetric Synthesis of α- and β-Amino Acids and β-Lactams. Acc. Chem. Res. 2003, 36, 10-19.
-
(2003)
Acc. Chem. Res.
, vol.36
, pp. 10-19
-
-
Taggi, A.E.1
Hafez, A.M.2
Lectka, T.3
-
41
-
-
0000475490
-
-
For previous examples of the use of ammonium enolates derived from cinchona alkaloids, see: (a) Pracejus, H.; Maetje, H. J. Prakt. Chem. 1964, 24, 195-205.
-
(1964)
J. Prakt. Chem.
, vol.24
, pp. 195-205
-
-
Pracejus, H.1
Maetje, H.2
-
42
-
-
0001119728
-
Asymmetric synthesis of (S)- and (R)-malic acid from ketene and chloral
-
(b) Wynberg, H.; Staring, E. G. Asymmetric Synthesis of (S)- and (R)-Malic Acid from Ketene and Chloral. J. Am. Chem. Soc. 1982, 104, 166-168.
-
(1982)
J. Am. Chem. Soc.
, vol.104
, pp. 166-168
-
-
Wynberg, H.1
Staring, E.G.2
-
43
-
-
0033576424
-
Nucleophilic metal complexes as acylation catalysts: Solvent-dependent "switch" mechanisms leading to the first catalyzed staudinger reaction
-
Wack, H.; Drury, W. J., III; Taggi, A. E.; Ferraris, D.; Lectka, T. Nucleophilic Metal Complexes as Acylation Catalysts: Solvent-Dependent "Switch" Mechanisms Leading to the First Catalyzed Staudinger Reaction. Org. Lett. 1999, 1, 1985-1988.
-
(1999)
Org. Lett.
, vol.1
, pp. 1985-1988
-
-
Wack, H.1
Drury III, W.J.2
Taggi, A.E.3
Ferraris, D.4
Lectka, T.5
-
44
-
-
84948256942
-
Rate enhancement effects in the DABCO-catalyzed synthesis of hydroxyalkenoate esters
-
Hydrogen bond contacts have been postulated to play similar roles in the Baylis-Hillman reaction: Ameer, F.; Drewes, S. E.; Freese, S.; Kaye, P. T. Rate Enhancement Effects in the DABCO-Catalyzed Synthesis of Hydroxyalkenoate Esters. Synth Commun. 1988, 18, 495-500.
-
(1988)
Synth. Commun.
, vol.18
, pp. 495-500
-
-
Ameer, F.1
Drewes, S.E.2
Freese, S.3
Kaye, P.T.4
-
45
-
-
0041878745
-
Nucleophilic chiral amines as catalysts in asymmetric synthesis
-
and references therein
-
France, S.; Guerin, D. J.; Miller, S. J.; Lectka, T. Nucleophilic Chiral Amines as Catalysts in Asymmetric Synthesis. Chem. Rev. 2003, 103, 2985-3012 and references therein.
-
(2003)
Chem. Rev.
, vol.103
, pp. 2985-3012
-
-
France, S.1
Guerin, D.J.2
Miller, S.J.3
Lectka, T.4
-
46
-
-
0034674972
-
Catalytic, asymmetric synthesis of β-lactams
-
Taggi, A. E.; Hafez, A. M.; Wack, H.; Young, B.; Drury, W. J., III; Lectka, T. Catalytic, Asymmetric Synthesis of β-Lactams. J. Am. Chem. Soc. 2000, 122, 7831-7832.
-
(2000)
J. Am. Chem. Soc.
, vol.122
, pp. 7831-7832
-
-
Taggi, A.E.1
Hafez, A.M.2
Wack, H.3
Young, B.4
Drury III, W.J.5
Lectka, T.6
-
47
-
-
4143131867
-
-
note
-
As previously shown, many of the pharmaceutically relevant β-lactams are monosubstituted in the α-position of the amide. One could foresee this moiety arising from the reaction of monasubstituted ketenes with imines.
-
-
-
-
48
-
-
0037067063
-
The development of the first catalyzed reaction of ketenes and imines: Catalytic, asymmetric synthesis of β-lactams
-
Taggi, A. E.; Hafez, A. M.; Wack, H.; Young, B.; Ferraris, D.; Lectka, T. The Development of the First Catalyzed Reaction of Ketenes and Imines: Catalytic, Asymmetric Synthesis of β-Lactams. J. Am. Chem. Soc. 2002, 124, 6626-6635.
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 6626-6635
-
-
Taggi, A.E.1
Hafez, A.M.2
Wack, H.3
Young, B.4
Ferraris, D.5
Lectka, T.6
-
49
-
-
0142059741
-
Bicarbonate salts as cost-effective bases for the synthesis of ketenes and their synthetic equivalents applied to the asymmetric synthesis of β-lactams
-
Shah, M. H.; France, S.; Lectka, T. Bicarbonate Salts as Cost-Effective Bases for the Synthesis of Ketenes and Their Synthetic Equivalents Applied to the Asymmetric Synthesis of β-Lactams. Synlett 2003, 12, 1937-1939.
-
(2003)
Synlett
, vol.12
, pp. 1937-1939
-
-
Shah, M.H.1
France, S.2
Lectka, T.3
-
50
-
-
0037037845
-
Molecular mechanics calculations as predictors of enantioselectivity for chiral nucleophile catalyzed reactions
-
Taggi, A. E.; Hafez, A. M.; Dudding, T.; Lectka, T. Molecular Mechanics Calculations as Predictors of Enantioselectivity for Chiral Nucleophile Catalyzed Reactions. Tetrahedron 2002, 58, 8351-8356.
-
(2002)
Tetrahedron
, vol.58
, pp. 8351-8356
-
-
Taggi, A.E.1
Hafez, A.M.2
Dudding, T.3
Lectka, T.4
-
51
-
-
0001209391
-
Catalytic, enantioselective alkylation of α-imino esters using late transition metal phosphine complexes as catalysts
-
(a) Ferraris, D.; Young, B.; Dudding, T.; Lectka, T. Catalytic, Enantioselective Alkylation of α-Imino Esters Using Late Transition Metal Phosphine Complexes as Catalysts. J. Am. Chem. Soc. 1998, 120, 4548-4540.
-
(1998)
J. Am. Chem. Soc.
, vol.120
, pp. 4548-4540
-
-
Ferraris, D.1
Young, B.2
Dudding, T.3
Lectka, T.4
-
52
-
-
0000603617
-
2
-
2. J. Org. Chem. 1998, 63, 6090-6091.
-
(1998)
J. Org. Chem.
, vol.63
, pp. 6090-6091
-
-
Ferraris, D.1
Young, B.2
Cox, C.3
Drury III, W.J.4
Dudding, T.5
Lectka, T.6
-
53
-
-
0032576117
-
Novel synthesis of α-amino acid derivatives through catalytic enantioselective ene reactions of α-imino esters
-
(c) Drury, W. J., III; Ferraris, D.; Cox, C.; Young, B.; Lectka, T. Novel Synthesis of α-Amino Acid Derivatives through Catalytic Enantioselective Ene Reactions of α-Imino Esters. J. Am. Chem. Soc. 1998, 120, 11006-11007.
-
(1998)
J. Am. Chem. Soc.
, vol.120
, pp. 11006-11007
-
-
Drury III, W.J.1
Ferraris, D.2
Cox, C.3
Young, B.4
Lectka, T.5
-
54
-
-
0033515594
-
Catalytic, enantioselective alkylations of N,O-acetals
-
(d) Ferraris, D.; Dudding, T.; Young, B.; Drury, W. J., III; Lectka, T. Catalytic, Enantioselective Alkylations of N,O-Acetals. J. Org. Chem. 1999, 64, 2168-2169.
-
(1999)
J. Org. Chem.
, vol.64
, pp. 2168-2169
-
-
Ferraris, D.1
Dudding, T.2
Young, B.3
Drury III, W.J.4
Lectka, T.5
-
55
-
-
0037045227
-
Catalytic, enantioselective alkylation of α-imino esters: The synthesis of nonnatural α-amino acid derivatives
-
(e) Ferraris, D.; Young, B.; Cox, C.; Dudding, T.; Drury, W. J. III; Ryzhkov, L.; Taggi, A. E.; Lectka, T. Catalytic, Enantioselective Alkylation of α-Imino Esters: The Synthesis of Nonnatural α-Amino Acid Derivatives. J. Am. Chem. Soc. 2002, 124, 67-77.
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 67-77
-
-
Ferraris, D.1
Young, B.2
Cox, C.3
Dudding, T.4
Drury III, W.J.5
Ryzhkov, L.6
Taggi, A.E.7
Lectka, T.8
-
56
-
-
0000516236
-
Metal- and ligand accelerated catalysis of the Baylis-Hillman reaction
-
Aggarwal, V. K.; Mereu, A.; Tarver, G. J.; McCague, R. Metal- and Ligand Accelerated Catalysis of the Baylis-Hillman Reaction. J. Org. Chem. 1998, 63, 7183-7189.
-
(1998)
J. Org. Chem.
, vol.63
, pp. 7183-7189
-
-
Aggarwal, V.K.1
Mereu, A.2
Tarver, G.J.3
McCague, R.4
-
57
-
-
0037007754
-
Bifunctional asymmetric catalysis: A tandem nucleophile/lewis acid promoted synthesis of β-lactams
-
France, S.; Wack, H.; Hafez, A. M.; Taggi, A. E.; Witsil, D. R.; Lectka, T. Bifunctional Asymmetric Catalysis: A Tandem Nucleophile/ Lewis Acid Promoted Synthesis of β-Lactams. Org. Lett. 2002, 4, 1603-1605.
-
(2002)
Org. Lett.
, vol.4
, pp. 1603-1605
-
-
France, S.1
Wack, H.2
Hafez, A.M.3
Taggi, A.E.4
Witsil, D.R.5
Lectka, T.6
-
58
-
-
4143053272
-
-
note
-
We have obtained IR evidence that supports metal chelation to the zwitterionic enolate intermediate formed by BQ and ketenes.
-
-
-
-
59
-
-
0035925178
-
Catalytic, asymmetric α-halogenation
-
(a) Wack, H.; Taggi, A. E.; Hafez, A. M.; Drury, W. J., III; Lectka, T. Catalytic, Asymmetric α-Halogenation J. Am. Chem. Soc. 2001, 123, 1531-1532.
-
(2001)
J. Am. Chem. Soc.
, vol.123
, pp. 1531-1532
-
-
Wack, H.1
Taggi, A.E.2
Hafez, A.M.3
Drury III, W.J.4
Lectka, T.5
-
60
-
-
1842555125
-
Catalytic, asymmetric α-chlorination of acid halides
-
in press
-
(b) France, S.; Wack, H.; Taggi, A. E.; Hafez, A. M.; Wagerle, T. R.; Shah, M. H.; Dusich, C. L.; Lectka, T. Catalytic, Asymmetric α-Chlorination of Acid Halides. J. Am. Chem. Soc., in press.
-
J. Am. Chem. Soc.
-
-
France, S.1
Wack, H.2
Taggi, A.E.3
Hafez, A.M.4
Wagerle, T.R.5
Shah, M.H.6
Dusich, C.L.7
Lectka, T.8
-
61
-
-
4143068856
-
-
submitted for publication
-
(a) Wack, H.; France, S.; Hafez, A. M.; Drury, W. J., III; Lectka, T. J. Org. Chem., submitted for publication.
-
J. Org. Chem.
-
-
Wack, H.1
France, S.2
Hafez, A.M.3
Drury III, W.J.4
Lectka, T.5
-
62
-
-
4143082337
-
-
Ph.D. Thesis, Johns Hopkins University, Baltimore, MD
-
(b) Wack, H. Ph.D. Thesis, Johns Hopkins University, Baltimore, MD, 2001.
-
(2001)
-
-
Wack, H.1
-
63
-
-
0016607472
-
Potential inhibitors of L-asparagine biosynthesis. 2. Chemistry and biological activity of β-hydoxyaspartic acid and its derivatives
-
(a) Mokotoff, M.; Bagaglio, J. F.; Parikh, B. S. Potential Inhibitors of L-Asparagine Biosynthesis. 2. Chemistry and Biological Activity of β-Hydoxyaspartic Acid and its Derivatives. J. Med. Chem. 1975, 18, 354-358.
-
(1975)
J. Med. Chem.
, vol.18
, pp. 354-358
-
-
Mokotoff, M.1
Bagaglio, J.F.2
Parikh, B.S.3
-
64
-
-
0034613643
-
Synthesis of optically-pure β-hydroxyaspartate derivatives as glutamate transport blockers
-
(b) Shimamoto, K.; Shigeri, Y.; Yasuda-Kamatani, Y.; Lebrun, B.; Yumoto, N.; Nakajima, T. Synthesis of Optically-Pure β-Hydroxyaspartate Derivatives as Glutamate Transport Blockers. Bioorg. Med. Chem. Lett. 2000, 10, 2407-2410.
-
(2000)
Bioorg. Med. Chem. Lett.
, vol.10
, pp. 2407-2410
-
-
Shimamoto, K.1
Shigeri, Y.2
Yasuda-Kamatani, Y.3
Lebrun, B.4
Yumoto, N.5
Nakajima, T.6
-
65
-
-
0037034309
-
A catalyst that plays multiple roles asymmetric synthesis of β-substituted aspartic acid derivatives through a four-stage, one-pot procedure
-
Dudding, T.; Hafez, A. M.; Taggi, A. E.; Wagerle, T. R.; Lectka, T. A Catalyst that Plays Multiple Roles: Asymmetric Synthesis of β-Substituted Aspartic Acid Derivatives through a Four-Stage, One-Pot Procedure. Org. Lett. 2002, 4, 387-390.
-
(2002)
Org. Lett.
, vol.4
, pp. 387-390
-
-
Dudding, T.1
Hafez, A.M.2
Taggi, A.E.3
Wagerle, T.R.4
Lectka, T.5
-
66
-
-
0037697025
-
A multistage one-pot procedure mediated by a single catalyst: A new approach to the catalytic asymmetric synthesis of β-amino acids
-
Hafez, A. M.; Dudding, T.; Wagerle, T. R.; Shah, M. H.; Taggi, A. E.; Lectka, T. A Multistage, One-Pot Procedure Mediated by a Single Catalyst: A New Approach to the Catalytic Asymmetric Synthesis of β-Amino Acids. J. Org. Chem. 2003, 68, 5819-5825.
-
(2003)
J. Org. Chem.
, vol.68
, pp. 5819-5825
-
-
Hafez, A.M.1
Dudding, T.2
Wagerle, T.R.3
Shah, M.H.4
Taggi, A.E.5
Lectka, T.6
-
67
-
-
0034649719
-
Column asymmetric catalysis for β-lactam synthesis
-
(a) Hafez, A. M.; Taggi, A. E.; Wack, H.; Drury, W. J., III; Lectka, T. Column Asymmetric Catalysis for β-Lactam Synthesis. Org. Lett. 2000, 2, 3963-3965.
-
(2000)
Org. Lett.
, vol.2
, pp. 3963-3965
-
-
Hafez, A.M.1
Taggi, A.E.2
Wack, H.3
Drury III, W.J.4
Lectka, T.5
-
68
-
-
0035823834
-
Asymmetric catalysis of sequentially-linked columns
-
(b) Hafez, A. M.; Taggi, A. E.; Dudding, T.; Lectka, T. Asymmetric Catalysis of Sequentially-Linked Columns. J. Am. Chem. Soc. 2001, 123, 10853-10859.
-
(2001)
J. Am. Chem. Soc.
, vol.123
, pp. 10853-10859
-
-
Hafez, A.M.1
Taggi, A.E.2
Dudding, T.3
Lectka, T.4
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