The soluble guanylyl cyclase inhibitor ODQ, 1H-[1,2,4]oxadiazolo[4,3-a] quinoxalin-1-one, dose-dependently reduces the threshold for isoflurane anesthesia in rats

Anesthesia and Analgesia

Volumn 99, Issue 3, 2004, Pages 752-757

  Cechova, Sylvia ^a   Pajewski, Thomas N ^a,b  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; GUANYLATE CYCLASE INHIBITOR; ISOFLURANE; METHYLENE BLUE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; ENZYME INHIBITION; HEMODYNAMIC MONITORING; INHALATION ANESTHESIA; INHIBITION KINETICS; MALE; MICRODIALYSIS; MINIMUM LUNG ALVEOLUS CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; STATISTICAL SIGNIFICANCE;

ANESTHETICS, INHALATION; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GUANYLATE CYCLASE; ISOFLURANE; MALE; N-METHYLASPARTATE; NITRIC OXIDE SYNTHASE; OXADIAZOLES; QUINOXALINES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 4143120192     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/01.ANE.0000132695.77191.F3     Document Type: Article

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