Prospective randomised controlled trial of an infection screening programme to reduce the rate of preterm delivery

British Medical Journal

Volumn 329, Issue 7462, 2004, Pages 371-374

  Kiss, Herbert ^a   Petricevic, Ljubomir ^a   Husslein, Peter ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CAREGIVER; CLINICAL TRIAL; COMPARATIVE STUDY; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DATA ANALYSIS; EVALUATION; FEMALE; FETUS WEIGHT; GRAM STAINING; HEALTH PROGRAM; HUMAN; INFECTION PREVENTION; INFECTION RATE; INTRAUTERINE INFECTION; MAJOR CLINICAL STUDY; MEDICAL SPECIALIST; MULTICENTER STUDY; PREGNANT WOMAN; PREMATURE LABOR; PRENATAL CARE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SAMPLE SIZE; SCREENING TEST; SECOND TRIMESTER PREGNANCY; SPONTANEOUS ABORTION; STATISTICAL ANALYSIS; VAGINA SMEAR; VAGINITIS;

EID: 4143092602     PISSN: 09598146     EISSN: None     Source Type: Journal    
DOI: 10.1136/bmj.38169.519653.eb     Document Type: Article

References (16)

1. St John EB, Nelson KG, Cliver SP, Bishnio RR, Goldenberg RL. Cost of neonatal care according to gestational age at birth and survival status. Am J Obstet Gynecol 2000;182:170-5.
2. Mercer BM, Goldenberg RL, Moawad AH, Meis PJ, Iams JD, Das AF, et al. The preterm prediction study: effect of gestational age and cause of preterm birth on subsequent obstetric outcome. Am J Obstet Gynecol 1999;181:1216-21.
3. Gibbs RS, Romero R, Hillier SL, Eschenbach DA, Sweet RL. A review of premature birth and subclinical infection. Am J Obstet Gynecol 1992;166:1515-28.
4. Hillier SL, Martius J, Krohn M, Kiviat N, Holmes KK, Eschenbach DA. A case-control study of chorioamnionic infection and histologic chorioamnionitis in prematurity. N Engl J Med 1988;319:972-8.
5. McGregor JA, French JI, Parker R, Draper D, Patterson E, Jones W, et al. Prevention of premature birth by screening and treatment for common genital tract infection: results of a prospective controlled evaluation. Am J Obstet Gynecol 1995;173:157-67.
6. Gravett MG, Nelson HP, DeRouen T, Critchlow C, Eschenbach DA, Holmes KK. Independent associations of bacterial vaginosis and chlamydia trachomatis infection with adverse pregnancy outcome. JAMA 1986;256:1899-903.
7. McGregor JA, French JI. Bacterial vaginosis in pregnancy. Obstet Gynecol Survey 2000;55(suppl):1-19.
8. Hay PE, Lamont RF, Taylor-Robinson D, Morgan DJ, Ison C, Pearson J. Abnormal bacterial colonisation of the genital tract and subsequent preterm delivery and late miscarriage. BMJ 1994;308:295-8.
9. Meis PJ, Goldenberg RL, Mercer B, Moawad A, Das A, McNellis D, et al. The preterm prediction study: significance of vaginal infections. Am J Obstet Gynecol 1995;173:1231-5.
10. Brocklehurst P, Hannah M, McDonald H. Interventions for treating bacterial vaginosis in pregnancy. Cochrane Database Syst Rev 2000;(2): CD000262.
11. Leitich H, Brunbauer M, Bodner-Adler B, Kaider A, Egarter C, Husslein P. Antibiotic treatment of bacterial vaginosis in pregnancy: a meta-analysis. Am J Obstet Gynecol 2003;188:752-8.
12. Carey JC, Klebanoff MA, Hauth JC, Hillier SL, Thom EA, Ernest JM, et al. Metronidazole to prevent preterm delivery in pregnant women with asymptomatic bacterial vaginosis. N Engl J Med 2000;342:534-40.
13. Cotch MF, Hillier SL, Gibbs RS, Eschenbach DA. Epidemiology and outcomes associated with moderate to heavy Candida colonization during pregnancy. Am J Obstet Gynecol 1998;178:374-80.
14. Nugent RP, Krohn MA, Hillier SL. Reliability of diagnosing bacterial vaginosis is improved by a standardized method of Gram stain interpretation. J Clin Microbiol 1991;29:297-301.
15. Ugwumadu A, Manyonda I, Ried F, Hay P. Effect of early oral clindamycin on late miscarriage and preterm delivery in asymptomatic women with abnormal vaginal flora and bacterial vaginosis: a randomised controlled trial. Lancet 2003;361:983-8.
16. Lamont RF, Dunchan SLB, Mandal D, Basset P. Intravaginal dindamycin to reduce preterm birth in women with abnormal genital tract flora. Obstet Gynecol 2003;101:516-22.