UV light increases vitamin C uptake by bovine lens epithelial cells

Molecular Vision

Volumn 10, Issue , 2004, Pages 533-536

  Corti, Alessandro ^a   Ferrari, Silvia Martina ^a   Lazzarotti, Alessandra ^a   Del Corso, Antonella ^a   Mura, Umberto ^a   Casini, Alessandro Francesco ^a   Paolicchi, Aldo ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; CARMUSTINE; CYSTEINE; DEHYDROASCORBIC ACID; GLUCOSE; GLUTATHIONE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; THIOREDOXIN REDUCTASE; ENZYME INHIBITOR;

ANALYSIS OF VARIANCE; ANIMAL CELL; ANTERIOR EYE SEGMENT; ANTIOXIDANT ACTIVITY; AQUEOUS HUMOR; ARTICLE; CATTLE; CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ACTIVITY; EPITHELIUM CELL; INCUBATION TIME; LENS EPITHELIUM; LINEAR REGRESSION ANALYSIS; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; ULTRAVIOLET C RADIATION; ANIMAL; CELL CULTURE; CYTOLOGY; LENS; METABOLISM; OXIDATION REDUCTION REACTION; RADIATION EXPOSURE; ULTRAVIOLET RADIATION;

ANIMALS; ASCORBIC ACID; CARMUSTINE; CATTLE; CELLS, CULTURED; DEHYDROASCORBIC ACID; ENZYME INHIBITORS; EPITHELIAL CELLS; GLUCOSE; GLUTATHIONE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; LENS, CRYSTALLINE; OXIDATION-REDUCTION; OXIDATIVE STRESS; ULTRAVIOLET RAYS;

EID: 4143074970     PISSN: 10900535     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Spector A. Oxidative stress-induced cataract: mechanism of action. FASEB J 1995; 9:1173-82.
2. Halliwell B, Gutteridge JMC. Free radicals in biology and medicine. 3rd ed. Oxford (UK): Clarendon Press; 1999.
3. McCarty CA, Taylor HR. A review of the epidemiologic evidence linking ultraviolet radiation and cataracts. Dev Ophthalmol 2002; 35:21-31.
4. Giblin FJ. Glutathione: a vital lens antioxidant. J Ocul Pharmacol Ther 2000; 16:121-35.
5. Varma SD, Bauer SA, Richards RD. Hexose monophosphate shunt in rat lens: stimulation by vitamin C. Invest Ophthalmol Vis Sci 1987; 28:1164-9.
6. Ringvold A. Aqueous humour and ultraviolet radiation. Acta Ophthalmol (Copenh) 1980; 58:69-82.
7. Blondin J, Baragi V, Schwartz E, Sadowski JA, Taylor A. Delay of UV-induced eye lens protein damage in guinea pigs by dietary ascorbate. J Free Radic Biol Med 1986; 2:275-81.
8. Koskela TK, Reiss GR, Brubaker RF, Ellefson RD. Is the high concentration of ascorbic acid in the eye an adaptation to intense solar irradiation? Invest Ophthalmol Vis Sci 1989; 30:2265-7.
9. Reddy VN, Giblin FJ, Lin LR, Chakrapani B. The effect of aqueous humor ascorbate on ultraviolet-B-induced DNA damage in lens epithelium. Invest Ophthalmol Vis Sci 1998; 39:344-50.
10. Winkler BS, Orselli SM, Rex TS. The redox couple between glutathione and ascorbic acid: a chemical and physiological perspective. Free Radic Biol Med 1994; 17:333-49.
11. Kern HL, Zolot SL. Transport of vitamin C in the lens. Curr Eye Res 1987; 6:885-96.
12. Sasaki H, Giblin FJ, Winkler BS, Chakrapani B, Leverenz V, Shu CC. A protective role for glutathione-dependent reduction of dehydroascorbic acid in lens epithelium. Invest Ophthalmol Vis Sci 1995; 36:1804-17.
13. Langham ME, Heald K. Factors affecting the concentration of ascorbic acid in the crystalline lens of cattle and rabbits. Biochem J 1956; 63:52-6.
14. Gloster J. Reaction between dehydroascorbic acid and dialysed lens extract in vitro. Br J Ophthalmol 1956; 40:536-44.
15. Rose C, Devamanoharan PS, Varma SD. Dehydroascorbate reductase activity in bovine lens. Int J Vitam Nutr Res 1995; 65:40-4.
16. Akatsuka I, Bando M, Obazawa H, Oka M, Takehana M, Kobayashi S. NADH-dependent dehydroascorbate reductase in the rabbit lens. Tokai J Exp Clin Med 2001; 26:25-32.
17. Riley MV. The chemistry of the aqueous humor. In: Anderson RE editor. Biochemistry of the eye. San Francisco (1833 Fillmore St., San Francisco 94115): Manuals Program, American Academy of Ophthalmology, 1983. p. 79-95.
18. Richer SP, Rose RC. Water soluble antioxidants in mammalian aqueous humor: interaction with UV B and hydrogen peroxide. Vision Res 1998; 38:2881-8.
19. Rumsey SC, Kwon O, Xu GW, Burant CF, Simpson I, Levine M. Glucose transporter isoforms GLUT1 and GLUT3 transport dehydroascorbic acid. J Biol Chem 1997; 272:18982-9.
20. Merriman-Smith BR, Krushinsky A, Kistler J, Donaldson PJ. Expression patterns for glucose transporters GLUT1 and GLUT3 in the normal rat lens and in models of diabetic cataract. Invest Ophthalmol Vis Sci 2003; 44:3458-66.
21. Rose RC, Bode AM. Ocular ascorbate transport and metabolism. Comp Biochem Physiol A 1991; 100:273-85.
22. Massey V, Williams CH Jr. On the reaction mechanism of yeast glutathione reductase. J Biol Chem 1965; 240:4470-80.
23. Habig WH, Pabst MJ, Jakoby WB. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J Biol Chem 1974; 249:7130-9.
24. Maellaro E, Del Bello B, Sugherini L, Santucci A, Comporti M, Casini AF. Purification and characterization of glutathione-dependent dehydroascorbate reductase from rat liver. Biochem J 1994; 301:471-6.
25. Rose RC, Bode AM. Analysis of water-soluble antioxidants by high-pressure liquid chromatography. Biochem J 1995; 306:101-5.
26. Tietze F. Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal Biochem 1969; 27:502-22.
27. Baker MA, Cerniglia GJ, Zaman A. Microtiter plate assay for the measurement of glutathione and glutathione disulfide in large numbers of biological samples. Anal Biochem 1990; 190:360-5.
28. Griffith OW. Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. Anal Biochem 1980; 106:207-12.
29. Frischer H, Ahmad T. Severe generalized glutathione reductase deficiency after antitumor chemotherapy with BCNU [1,3-bis(chloroethyl)-1-nitrosourea]. J Lab Clin Med 1977; 89:1080-91.
30. Fernando MR, Satake M, Monnier VM, Lou MF. Thioltranferase mediated ascorbate recycling in human lens epithelial cells. Invest Ophthalmol Vis Sci 2004; 45:230-7.
31. Ringvold A, Anderssen E, Kjonniksen I. Distribution of ascorbate in the anterior bovine eye. Invest fOphthalmol Vis Sci 2000; 41:20-3.