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Volumn 24, Issue 8, 2004, Pages 647-657

Stimulation by carnitine of branched-chain α-keto acid dehydrogenase in intact heart mitochondria of rats

Author keywords

Branched chain amino acid oxidation; Branched chain keto acid dehydrogenase; Carnitine; Carnitine acyl transferase II

Indexed keywords

2 BROMOPALMITIC ACID; 2 OXOISOVALERATE DEHYDROGENASE (LIPOAMIDE); 2 OXOISOVALERIC ACID; 4 PENTENOIC ACID; ACYL COENZYME A; ALPHA ISOBUTYRYL COENZYME A; CARBON 14; CARNITINE; CARNITINE ACYL TRANSFERASE II; CARNITINE ACYLTRANSFERASE; CARNITINE DERIVATIVE; COENZYME A; ESTER DERIVATIVE; OCTANOIC ACID; OCTANOYLCARNITINE; UNCLASSIFIED DRUG;

EID: 4143074916     PISSN: 02715317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nutres.2003.11.012     Document Type: Article
Times cited : (1)

References (41)
  • 1
    • 0018790832 scopus 로고
    • Leucine degradation in cell-free extracts of skeletal muscle
    • Odessey R.A., Goldberg L. Leucine degradation in cell-free extracts of skeletal muscle. Biochem J. 178:1979;475-489
    • (1979) Biochem J , vol.178 , pp. 475-489
    • Odessey, R.A.1    Goldberg, L.2
  • 2
    • 0018119866 scopus 로고
    • 2+ uptake coupled to electron transport in rat heart mitochondria
    • 2+ uptake coupled to electron transport in rat heart mitochondria. J Biol Chem. 253:1978;6379-6385
    • (1978) J Biol Chem , vol.253 , pp. 6379-6385
    • Vercesi, A.1    Reynafarje, B.2    Lehninger, A.L.3
  • 4
    • 0015524231 scopus 로고
    • Oxidation of branched-chain amino acids by isolated hearts and diaphragms of the rat
    • Buse M.G., Biggers J.F., Friderici K.H., Buse J.F. Oxidation of branched-chain amino acids by isolated hearts and diaphragms of the rat. J Biol Chem. 247:1972;8085-8096
    • (1972) J Biol Chem , vol.247 , pp. 8085-8096
    • Buse, M.G.1    Biggers, J.F.2    Friderici, K.H.3    Buse, J.F.4
  • 5
    • 0018578843 scopus 로고
    • Studies on the regulation of the branched-chain α-keto acid dehydrogenase in the perfused rat heart
    • Buffington C.K., Debuysere M.S., Olson M.S. Studies on the regulation of the branched-chain α-keto acid dehydrogenase in the perfused rat heart. J Biol Chem. 254:1979;10453-10458
    • (1979) J Biol Chem , vol.254 , pp. 10453-10458
    • Buffington, C.K.1    Debuysere, M.S.2    Olson, M.S.3
  • 6
    • 4143060985 scopus 로고
    • Catabolism of the carbon skeletons of amino acids
    • Los Altos, CA: Lange Medical Publications
    • Rodwell VW. Catabolism of the carbon skeletons of amino acids. In: Harper's review of biochemistry, 19th ed. Los Altos, CA: Lange Medical Publications, 1983. p. 283-306
    • (1983) Harper's Review of Biochemistry, 19th Ed. , pp. 283-306
    • Rodwell, V.W.1
  • 7
    • 0024956076 scopus 로고
    • Thoughts on the role of Branched chain keto alpha-keto acid dehydrogenase complex in nitrogen metabolism
    • Harper A.E. Thoughts on the role of Branched chain keto alpha-keto acid dehydrogenase complex in nitrogen metabolism. Ann NY Acad Sci. 573:1989;267-273
    • (1989) Ann NY Acad Sci , vol.573 , pp. 267-273
    • Harper, A.E.1
  • 8
    • 0029814960 scopus 로고    scopus 로고
    • Carnitine and physical exercise
    • Heinonen O.J. Carnitine and physical exercise. Sports Med. 22:1996;109-132
    • (1996) Sports Med , vol.22 , pp. 109-132
    • Heinonen, O.J.1
  • 9
    • 0021710439 scopus 로고
    • Urinary excretion of L-carnitine and acylcarnitines by patients with disorders of organic acid metabolism: Evidence for secondary insufficiency of L-carnitine
    • Chalmers R.A., Roe C.R., Stacey T.E., Hoppel C.L. Urinary excretion of L-carnitine and acylcarnitines by patients with disorders of organic acid metabolism evidence for secondary insufficiency of L-carnitine. Pediatr Res. 18:1984;1325-1328
    • (1984) Pediatr Res , vol.18 , pp. 1325-1328
    • Chalmers, R.A.1    Roe, C.R.2    Stacey, T.E.3    Hoppel, C.L.4
  • 10
    • 0018140016 scopus 로고
    • The effect of acylcarnitines on the oxidation of branched-chain α-keto acids in mitochondria
    • Bremer J., Davis E.J. The effect of acylcarnitines on the oxidation of branched-chain α-keto acids in mitochondria. Biochim Biophys Acta. 528:1978;269-275
    • (1978) Biochim Biophys Acta , vol.528 , pp. 269-275
    • Bremer, J.1    Davis, E.J.2
  • 11
    • 0018169004 scopus 로고
    • Effect of L-carnitine on the oxidation of leucine and valine by rat skeletal muscle
    • Van Hinsbergh V.W., Veerkamp J.H., Engelen P.J.M., Ghijsen W.J. Effect of L-carnitine on the oxidation of leucine and valine by rat skeletal muscle. Biochem Med. 20:1978;115-124
    • (1978) Biochem Med , vol.20 , pp. 115-124
    • Van Hinsbergh, V.W.1    Veerkamp, J.H.2    Engelen, P.J.M.3    Ghijsen, W.J.4
  • 12
    • 0019125735 scopus 로고
    • Mechanism of the stimulation of branched-chain oxoacid oxidation in liver by carnitine
    • May M.E., Aftring R.P., Buse M.G. Mechanism of the stimulation of branched-chain oxoacid oxidation in liver by carnitine. J Biol Chem. 255:1980;8394-8397
    • (1980) J Biol Chem , vol.255 , pp. 8394-8397
    • May, M.E.1    Aftring, R.P.2    Buse, M.G.3
  • 13
    • 0025372395 scopus 로고
    • The role of carnitine in intracellular metabolism
    • Bremer J. The role of carnitine in intracellular metabolism. J Clin Chem Clin Biochem. 28:1990;297-301
    • (1990) J Clin Chem Clin Biochem , vol.28 , pp. 297-301
    • Bremer, J.1
  • 14
    • 0021024932 scopus 로고
    • Carnitine - Metabolism and functions
    • Bremer J. Carnitine - metabolism and functions. Physiol Rev. 63:1983;1420-1480
    • (1983) Physiol Rev , vol.63 , pp. 1420-1480
    • Bremer, J.1
  • 15
    • 0017858583 scopus 로고
    • Role of carnitine in leucine oxidation by mitochondria of rat muscle
    • Van Hinsbergh V.W., Veerkamp J.H., Zuurveld P.J.G.E.M. Role of carnitine in leucine oxidation by mitochondria of rat muscle. FEBS lett. 92:1978;100-104
    • (1978) FEBS Lett , vol.92 , pp. 100-104
    • Van Hinsbergh, V.W.1    Veerkamp, J.H.2    Zuurveld, P.J.G.E.M.3
  • 16
    • 0020371958 scopus 로고
    • Possible functions of short-chain and medium-chain carnitine acyltransferases
    • Bieber L.L., Emaus R., Valkner Farrell K. Possible functions of short-chain and medium-chain carnitine acyltransferases. Fed Proc. 41:1982;2858-2862
    • (1982) Fed Proc , vol.41 , pp. 2858-2862
    • Bieber, L.L.1    Emaus, R.2    Valkner Farrell, K.3
  • 17
    • 0014961081 scopus 로고
    • Formation of branched chain acylcarntines in mitochondria
    • Solberg H.E., Bremer J. Formation of branched chain acylcarntines in mitochondria. Biochim Biophys Acta. 222:1970;372-380
    • (1970) Biochim Biophys Acta , vol.222 , pp. 372-380
    • Solberg, H.E.1    Bremer, J.2
  • 18
    • 0018249747 scopus 로고
    • Effect of carnitine on branched-chain amino acid oxidation by liver and skeletal muscle
    • Paul H.S., Adibi S.A. Effect of carnitine on branched-chain amino acid oxidation by liver and skeletal muscle. Am J Physiol. 234:1978;E494-499
    • (1978) Am J Physiol , vol.234 , pp. 494-499
    • Paul, H.S.1    Adibi, S.A.2
  • 19
    • 0022258493 scopus 로고
    • Interaction of short-chain and branched-chain fatty acids and their carnitine and CoA esters and of various metabolites and agents with branched-chain 2-oxo acid oxidation in rat muscle and liver and mitochondria
    • Veerkamp J.H., Van Moerkerk H.T.B., Wagenmakers A.J.M. Interaction of short-chain and branched-chain fatty acids and their carnitine and CoA esters and of various metabolites and agents with branched-chain 2-oxo acid oxidation in rat muscle and liver and mitochondria. Int J Biochem. 17:1985;967-974
    • (1985) Int J Biochem , vol.17 , pp. 967-974
    • Veerkamp, J.H.1    Van Moerkerk, H.T.B.2    Wagenmakers, A.J.M.3
  • 20
    • 0025776811 scopus 로고
    • Copper deficiency in a genetically hypertensive cardiomyopathic rat: Electrogram, functional and ultrastructural aspects
    • Medeiros D.M., Liao Z., Hamlin R.L. Copper deficiency in a genetically hypertensive cardiomyopathic rat electrogram, functional and ultrastructural aspects. J Nutr. 121:1991;1026-1034
    • (1991) J Nutr , vol.121 , pp. 1026-1034
    • Medeiros, D.M.1    Liao, Z.2    Hamlin, R.L.3
  • 21
    • 0018718909 scopus 로고
    • 4-Methyl-2-oxopentanoate oxidation by rat skeletal-muscle mitochondria
    • Van Hinsbergh V.W., Veerkamp J.H., Glatz J.F.C. 4-Methyl-2-oxopentanoate oxidation by rat skeletal-muscle mitochondria. Biochem J. 182:1979;353-360
    • (1979) Biochem J , vol.182 , pp. 353-360
    • Van Hinsbergh, V.W.1    Veerkamp, J.H.2    Glatz, J.F.C.3
  • 22
    • 0024230519 scopus 로고
    • Assay of total complex and activity state of branched chain α-keto acid dehydrogenase complex and of activator protein in mitochondria, cells and tissues
    • Patston P.A., Espinal J., Beggs M., Randle P.J. Assay of total complex and activity state of branched chain α-keto acid dehydrogenase complex and of activator protein in mitochondria, cells and tissues. Methods Enzymol. 166:1988;175-189
    • (1988) Methods Enzymol , vol.166 , pp. 175-189
    • Patston, P.A.1    Espinal, J.2    Beggs, M.3    Randle, P.J.4
  • 23
    • 0024269465 scopus 로고
    • Determination of activity and activity state of Branched chain α-keto acid dehydrogenase in rat tissues
    • Goodwin G.W., Zhang B., Paxton R., Harris R.A. Determination of activity and activity state of Branched chain α-keto acid dehydrogenase in rat tissues. Methods Enzymol. 166:1988;189-201
    • (1988) Methods Enzymol , vol.166 , pp. 189-201
    • Goodwin, G.W.1    Zhang, B.2    Paxton, R.3    Harris, R.A.4
  • 24
    • 0019751507 scopus 로고
    • Protein determination in membrane and lipoprotein samples: Manual and automated procedures
    • Markwell M.A.K., Haas S.M., Tolbert N.E., Bieber L.L. Protein determination in membrane and lipoprotein samples manual and automated procedures. Methods Enzymol. 72:1981;296-303
    • (1981) Methods Enzymol , vol.72 , pp. 296-303
    • Markwell, M.A.K.1    Haas, S.M.2    Tolbert, N.E.3    Bieber, L.L.4
  • 25
    • 0019643636 scopus 로고
    • Role of carnitine in branched chain keto acid metabolism
    • Role of carnitine in branched chain keto acid metabolism. Nutr Rev 1981;39:406-7
    • (1981) Nutr Rev , vol.39 , pp. 406-407
  • 26
    • 0016136469 scopus 로고
    • Studies with (+)-octanoylcarnitine in experimental diabetic ketoacidosis
    • McGarry J.D., Foster D.W. Studies with (+)-octanoylcarnitine in experimental diabetic ketoacidosis. Diabetes. 23:1974;485-493
    • (1974) Diabetes , vol.23 , pp. 485-493
    • McGarry, J.D.1    Foster, D.W.2
  • 27
    • 0014807629 scopus 로고
    • Control factors affecting gluconeogenesis in perfused rat liver
    • Williamson J.R., Rostand S.G., Peterson M.J. Control factors affecting gluconeogenesis in perfused rat liver. J Biol Chem. 245:1970;3242-3251
    • (1970) J Biol Chem , vol.245 , pp. 3242-3251
    • Williamson, J.R.1    Rostand, S.G.2    Peterson, M.J.3
  • 28
    • 0015807112 scopus 로고
    • Biochemical effects of the hypoglycemic compound pent-4-enoic acid and related nonhypoglycemic fatty acids. Effects of the free acids and their carnitine on coenzyme a dependent oxidations in rat liver mitochondria
    • Holland P.C., Sherratt H.S.A. Biochemical effects of the hypoglycemic compound pent-4-enoic acid and related nonhypoglycemic fatty acids. Effects of the free acids and their carnitine on coenzyme A dependent oxidations in rat liver mitochondria. Biochem J. 136:1973;157-171
    • (1973) Biochem J , vol.136 , pp. 157-171
    • Holland, P.C.1    Sherratt, H.S.A.2
  • 29
    • 0021163908 scopus 로고
    • Interaction of octanoate with branched chain 2-oxo acid oxidation in rat and human muscle in vitro
    • Wagenmakers A.J.M., Veerkamp J.H. Interaction of octanoate with branched chain 2-oxo acid oxidation in rat and human muscle in vitro. Int J Biochem. 16:1984;977-984
    • (1984) Int J Biochem , vol.16 , pp. 977-984
    • Wagenmakers, A.J.M.1    Veerkamp, J.H.2
  • 30
    • 0019157971 scopus 로고
    • Degradation of branched-chain amino acids and 2-oxo acids in human and rat muscle
    • Veerkamp J.H., Van Hinsbergh V.W.M., Cordewener J.H.G. Degradation of branched-chain amino acids and 2-oxo acids in human and rat muscle. Biochem Med. 24:1980;118-129
    • (1980) Biochem Med , vol.24 , pp. 118-129
    • Veerkamp, J.H.1    Van Hinsbergh, V.W.M.2    Cordewener, J.H.G.3
  • 31
    • 0019187791 scopus 로고
    • Effect of carnitine and branched-chain acylcarnitines on the 2-oxo acid dehydrogenase activity in intact mitochondria of rat muscle
    • Van Hinsbergh V.W.M., Veerkamp J.H., Cordewener J.H.G. Effect of carnitine and branched-chain acylcarnitines on the 2-oxo acid dehydrogenase activity in intact mitochondria of rat muscle. Int J Biochem. 12:1980;559-565
    • (1980) Int J Biochem , vol.12 , pp. 559-565
    • Van Hinsbergh, V.W.M.1    Veerkamp, J.H.2    Cordewener, J.H.G.3
  • 32
    • 0018956385 scopus 로고
    • Leucine metabolism in skeletal muscle of the tumor-bearing rat
    • Goodlad G.A.J., Clark C.M. Leucine metabolism in skeletal muscle of the tumor-bearing rat. Eur J Cancer. 16:1980;1153-1162
    • (1980) Eur J Cancer , vol.16 , pp. 1153-1162
    • Goodlad, G.A.J.1    Clark, C.M.2
  • 33
    • 0019447721 scopus 로고
    • Oxidation of branched-chain amino acids in skeletal muscle and liver of rat
    • Spydevold O., Hokland B. Oxidation of branched-chain amino acids in skeletal muscle and liver of rat. Biochim Biophys Acta. 676:1981;279-288
    • (1981) Biochim Biophys Acta , vol.676 , pp. 279-288
    • Spydevold, O.1    Hokland, B.2
  • 34
    • 0020637727 scopus 로고
    • Release of leucine and isoleucine metabolites by perfused skeletal muscle and liver of rat
    • Spydevold O., Hokland B. Release of leucine and isoleucine metabolites by perfused skeletal muscle and liver of rat. Int J Biochem. 15:1983;985-990
    • (1983) Int J Biochem , vol.15 , pp. 985-990
    • Spydevold, O.1    Hokland, B.2
  • 35
    • 0019131097 scopus 로고
    • Studies on the activation and inactivation of the branched-chain α-keto acid dehydrogenase in the perfused rat heart
    • Waymack P.P., DeBuysere M.S., Olson M.S. Studies on the activation and inactivation of the branched-chain α-keto acid dehydrogenase in the perfused rat heart. J Biol Chem. 255:1980;9773-9781
    • (1980) J Biol Chem , vol.255 , pp. 9773-9781
    • Waymack, P.P.1    Debuysere, M.S.2    Olson, M.S.3
  • 36
    • 0018595707 scopus 로고
    • Effects of branched chain α-keto acids on the metabolism of isolated rat liver cells: I. Regulation of branched chain α-keto acid metabolism
    • Williamson J.R., Rostand S.G., Peterson M.J. Effects of branched chain α-keto acids on the metabolism of isolated rat liver cells I. Regulation of branched chain α-keto acid metabolism. J Biol Chem. 254:1979;11511-11520
    • (1979) J Biol Chem , vol.254 , pp. 11511-11520
    • Williamson, J.R.1    Rostand, S.G.2    Peterson, M.J.3
  • 37
    • 0022261592 scopus 로고
    • The metabolic fate of branched-chain amino acids and 2-oxo acids in rat muscle homogenates and diaphragms
    • Wagenmakers A.J.M., Salden H.J.M., Veerkamp J.H. The metabolic fate of branched-chain amino acids and 2-oxo acids in rat muscle homogenates and diaphragms. Int J Biochem. 17:1985;957-965
    • (1985) Int J Biochem , vol.17 , pp. 957-965
    • Wagenmakers, A.J.M.1    Salden, H.J.M.2    Veerkamp, J.H.3
  • 38
    • 0022639126 scopus 로고
    • Amino acid catabolism by perfused rat hindquarter. the metabolic fates of valine
    • Lee S.-H.C., Davis E.J. Amino acid catabolism by perfused rat hindquarter. The metabolic fates of valine. Biochem J. 233:1986;621-630
    • (1986) Biochem J , vol.233 , pp. 621-630
    • Lee, S.-H.C.1    Davis, E.J.2
  • 39
    • 0025075729 scopus 로고
    • Oxidation of 2-oxoisocaproate and 2-oxoisovalerate by the perfused rat heart. Interactions with fatty acid oxidation
    • Letto J., Brosnan J.T., Brosnan M.E. Oxidation of 2-oxoisocaproate and 2-oxoisovalerate by the perfused rat heart. Interactions with fatty acid oxidation. Biochem Cell Biol. 68:1989;260-265
    • (1989) Biochem Cell Biol , vol.68 , pp. 260-265
    • Letto, J.1    Brosnan, J.T.2    Brosnan, M.E.3
  • 40
    • 0022464411 scopus 로고
    • Carnitine metabolism and function in humans
    • Rebouche C.J., Paulson D.J. Carnitine metabolism and function in humans. Annu Rev Nutr. 6:1986;41-66
    • (1986) Annu Rev Nutr , vol.6 , pp. 41-66
    • Rebouche, C.J.1    Paulson, D.J.2
  • 41
    • 0023204259 scopus 로고
    • 3-Hydroxy-3-methylglutaric aciduria: Response to carnitine therapy and fat and leucine restriction
    • Dasouki M., Buchanan D., Mercer N., Gibson K.M., Theone J. 3-Hydroxy-3-methylglutaric aciduria response to carnitine therapy and fat and leucine restriction. J Inher Metab Dis. 10:1987;142-146
    • (1987) J Inher Metab Dis , vol.10 , pp. 142-146
    • Dasouki, M.1    Buchanan, D.2    Mercer, N.3    Gibson, K.M.4    Theone, J.5


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