Persistent itching nodules after the fourth dose of diphtheria-tetanus toxoid vaccines without evidence of delayed hypersensitivity to aluminium

Vaccine

Volumn 22, Issue 27-28, 2004, Pages 3698-3706

  Netterlid, E ^a   Bruze, M ^b   Hindsen M ^b   Isaksson, M ^b   Olin, P ^a  

^a SWEDISH INSTITUTE FOR INFECTIOUS DISEASE CONTROL   (Sweden)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Aluminium contact allergy; DT vaccine booster; Persistent local reactions

Indexed keywords

ALUMINUM; DIPHTHERIA TETANUS VACCINE; DITEBOOSTER; DUPLEX;

ARTICLE; CLINICAL TRIAL; CONTACT ALLERGY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; DIPHTHERIA; EXOSTOSIS; HUMAN; INJECTION SITE; MAJOR CLINICAL STUDY; PATCH TEST; PRIORITY JOURNAL; PRURITUS; RANDOMIZED CONTROLLED TRIAL; SCHOOL; SCHOOL CHILD; SKIN NODULE; STATISTICAL SIGNIFICANCE; SWEDEN; TETANUS; VACCINATION;

ADJUVANTS, IMMUNOLOGIC; ALUMINUM; CHILD; DIPHTHERIA-TETANUS-PERTUSSIS VACCINE; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYPERSENSITIVITY, DELAYED; IMMUNIZATION, SECONDARY; INFANT; MALE; PRODUCT SURVEILLANCE, POSTMARKETING; PRURITUS; QUESTIONNAIRES; SKIN; SKIN TESTS;

EID: 4143069191     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2004.03.036     Document Type: Article

References (19)

1. Bergfors E., Trollfors B., Inerot A. Unexpectedly high incidence of persistent itching nodules and delayed hypersensitivity to aluminium in children after the use of adsorbed vaccines from a single manufacturer. Vaccine. 22:2003;64-69
2. Frost L., Johansen P., Pedersen S., Veien N., Aabel Østergaard P., Nielsen M.H. Persistent subcutaneous nodules in children hyposensitized with aluminium-containing allergen extracts. Allergy. 40:1985;368-372
3. Böhler-Sommeregger K., Lindemayr H. Contact sensitivity to aluminium. Contact Dermat. 15:1986;278-281
4. Nielsen A.O., Kaaber K., Veien N.K. Aluminiumallergi forårsaget af Di-Te-Pol-vaccine. Ugeskr Læger. 154:1992;1900-1901
5. Blennow M., Granström M., Strandell A. Adverse reaction after diphtheria-tetanus booster in 10 year-old schoolchildren in relation to the type of vaccine given for the primary vaccination. Vaccine. 5:1994;427-430
6. Mark A., Granström M. The role of aluminium for adverse reactions and immunogenicity of diphtheria-tetanus booster vaccine. Acta Pædiatr. 82:1993;159-163
7. Trollfors B., Taranger J., Lagergard T., et al. A Placebo-controlled trial of a pertussis-toxoid vaccine. N Engl J Med. 333:1995;1045-1050
8. Wahlberg JE. Patch testing. In: Rycroft RJG, Menné T, Frosch PJ, Lepoittevin, J-P, editors. Textbook of contact dermatitis. 3rd ed. Berlin, Heidelberg, New York: Springer Verlag; 2001. p. 435-68.
9. Wilkinson D.S., Fregert S., Magnusson B., et al. Terminology of contact dermatitis. Acta Derm. Venereol. 50:1970;287-292
10. Hayes R.J., Bennett S. Simple sample size calculation for cluster-randomized trials. Int J Epid. 28:1999;319-326
11. Gherardi R.K., Coquet M., Cherin P., et al. Macrophagic myofasciitis: an emergin entity. Lancet. 352:1998;347-352
12. Gherardi R.K., Coquet M., Cherin P., et al. Macrophagic myofasciitis lesions assess long-term persistence of vaccine-derived aluminium hydroxide in muscle. Brain. 124:2001;1821-1831
13. Lacson A.G., D'Cruz C.A., Gilbert-Barness E., Sharere L., Jacinto S., Cuenca R. Aluminium phagocytosis in quadriceps muscle following vaccination in children: relationship to macrophagic myofasciitis. Pediatr Develop Pathol. 5:2002;151-158
14. Rennels M.B., Deloria M.A., Pichichero M.E., et al. Lack of consistent relationship between quantity of aluminium in diphtheria-tetanus-acellular pertussis vaccines and rates of extensive swelling reactions. Vaccine. 20:2002;S44-S47
15. Rønne T. Vaccination granulomas. Epi-News. 16:1999;1
16. Kaaber K., Otkjær Nielsen A., Veien N.K. Vaccination granulomas and aluminium allergy: course and prognostic factors. Contact Dermat. 26:1992;304-306
17. Hewlett EL. Preparation and composition of acellular pertussis vaccines. Considerations of potential effects on vaccine efficacy. In: Brown E, Greco D, Mastrantonio P, Salmaso S, editors. Pertussis vaccine trials, Basel. Dev Biol Stand 1997;89:143-51.
18. Duchén K., Granström M., Hedenskog S., Blennow M., Björkstén M. Immunoglobulin E and G responses to pertussis toxin in children immunised with adsorbed and non-adsorbed whole cell pertussis vaccines. Vaccine. 15:1997;1558-1561
19. Jefferson T., Rudin M., Di Pietrantonj C. Adverse events after immunisation with aluminium-containing DTP vaccines: systematic review of the evidence. Lancet Infect. Dis. 4:2004;84-90