Quantitation of angiogenesis and its correlation with vascular endothelial growth factor expression in astrocytic tumors

Analytical and Quantitative Cytology and Histology

Volumn 26, Issue 4, 2004, Pages 223-229

  Gupta, Kirti ^b   Radotra, Bishan D ^a   Banerjee, Ashru K ^b   Nijhawan, Raje ^b  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

^b Department of Histopathology ^*

Author keywords

Angiogenesis; Astrocytoma; Pathologic; Vascular endothelial growth factor

Indexed keywords

CD31 ANTIGEN; TUMOR MARKER; VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; ASTROCYTOMA; CANCER GRADING; CANCER GROWTH; CAPILLARY DENSITY; CONTROLLED STUDY; CORRELATION ANALYSIS; GLIOMA; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; INTRATUMORAL MICROVESSEL DENSITY; MICROVASCULATURE; PILOCYTIC ASTROCYTOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SCORING SYSTEM; TISSUE SECTION; TUMOR VASCULARIZATION; WORLD HEALTH ORGANIZATION;

ASTROCYTOMA; BRAIN NEOPLASMS; HUMANS; IMMUNOHISTOCHEMISTRY; MICROCIRCULATION; NEOVASCULARIZATION, PATHOLOGIC; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 4143052385     PISSN: 08846812     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Abdulrauf SI, Edvardsen K, Ho KL: Vascular endothelial growth factor expression and vascular density as prognositc markers of survival in patients with low grade astrocytoma. J Neurosurg 1998;88:513-520
2. Assimakopoulou M, Sotiropoulou BG, Maraziotis T, Papadakis N, Varakis I: Microvessel density in brain tumors. Anticancer Res 1997;17:4747-4753
3. Barbareschi, M, Gasparini G, Morelli L, Forti S, Dalla Palma P: Novel methods for the determination of the angiogenic activity of human tumors. Breast Cancer Res Treat 1995;36: 181-192
4. Bian XW, Du LL, Shi JQ, Cheng YS, Liu FX: Correlation of bFGF, FGFR-1 and VEGF expression with vascularity and malignancy of human astrocytomas. Analyt Quant Cytol Histol 2000;22:267-274
5. Chan AS, Leung SY, Wong MP, Yuen ST, Cheung N, Fan YW, Chung LP: Expression of vascular endothelial growth factor and its receptors in the anaplastic progression of astrocytoma, oligodendroglioma, and ependymoma. Am J Surg Pathol 1998;22:816-826
6. Daumas-Duport C, Scheithauer B, O'Fallon J, Kelly P: Grading of astrocytomas: A simple and reproducible method. Cancer 1988;62:2152-2165
7. Ferrara N, Houck KA, Jakeman LB, Winer J, Leung DW: The vascular endothelial growth factor family of polypeptides. J Cell Biochem 1991;47:211-218
8. Folkman J: Tumour angiogenesis: Therapeutic implications. N Engl J Med 1971;285:1182-1186
9. Folkman J, Klagsburn M: Angiogenic factors. Science 1987;235:442-447
10. Kleihues P, Burger PC, Scheithauer BW: The new WHO classification of brain tumors. Brain Pathol 1993;3:255-268
11. Korkolopoulou P, Patsouris E, Kavantzas N, Konstantinidou AE, Christodoulou P, Thomas-Tsagli E, Pananikolaou A, Eftychiadis C, Pavlopoulos PM, Angelidakis D, Rologis D, Davaris P: Prognostic implications of microvessel morphometry is diffuse astrocytic neoplasms. Neuropathol Appl Neurobiol 2002;28:57-66
12. Leon SP, Folkerth RD, Black PM: Microvessel density is a prognostic indicator for patients with astroglial brain tumors. Cancer 1996;77:362-372
13. Macchiarini P, Fontanini G, Hardin MJ, Squartini F, Angeletti CA: Relation of neovascularization to metastasis of non-small cell lung cancer. Lancet 1992;340:145-146
14. Pietsch T, Valter MM, Wolf HK, von Deimling A, Huang HJ, Cavenee WK, Wiestler OD: Expression and distribution of vascular endothelial growth factor protein in human brain tumors. Acta Neuropathol 1997;93:109-117
15. Plate KH, Breier G, Weich HA, Mennel HD, Risau W: Vascular endothelial growth factor and glioma angiogenesis. Int J Cancer 1994;59:520-529
16. Plate KH, Breier G, Weich HA, Risau W: Vascular endothelial growth factor is a potential tumor angiogenesis factor in human gliomas in vivo. Nature 1992;359:845-848
17. Robinson CJ, Stringer SE: The splice variants of VEGF and its receptors. J Cell Sci 2001;114:853-865
18. Takekawa Y, Sawada Y: Vascular endothelial growth factor and neovascularization in astrocytic tumors. Pathol Int 1998;48:109-114
19. Weidner N: Current pathologic methods for measuring intra-tumoral microvessel density within breast carcinoma and other solid tumors. Br Cancer Res Treat 1995;36:169-180
20. Weidner N, Folkman J, Pozza F, Bevilaequa P, Allred EN, Moore DH, Meli S, Gasparini G: Tumor angiogenesis: A new significant and independent prognostic indicator in early-stage breast carcinoma. J Natl Cancer Inst 1992;84:1875-1887
21. Wesseling P, van der Laak JA, Link M, Teepen HL, Ruiter DJ: Quantitative analysis of malignancy. Hum Pathol 1998;29: 352-358