A role for topical insulin in the management problematic surgical wounds

Annals of the Royal College of Surgeons of England

Volumn 90, Issue 2, 2008, Pages 160-

  Wilson, J M ^a   Baines, R ^a   Babu, E D ^a   Kelley, C J ^a  

^a HILLINGDON HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; NEUTRAL INSULIN; SODIUM CHLORIDE;

AGED; ARTICLE; CASE REPORT; DOSE RESPONSE; FEMALE; HUMAN; HYPERGLYCEMIA; LAPAROTOMY; NONHUMAN; SURGICAL WOUND; WOUND; WOUND DRESSING; WOUND HEALING IMPAIRMENT; WOUND IRRIGATION;

ADMINISTRATION, TOPICAL; AGED, 80 AND OVER; ANIMALS; FEMALE; HUMANS; INSULIN; LAPAROTOMY; SURGICAL WOUND DEHISCENCE;

EID: 41349108041     PISSN: 00358843     EISSN: None     Source Type: Journal    
DOI: 10.1308/003588408X261816     Document Type: Article

References (7)

1. Hanam SR, Singleton CE, Rudek W. The effect of topical insulin on infected cutaneous ulcerations in diabetic and nondiabetic mice. J Foot Surg 1983; 22: 298-301.
2. Zhang XJ, Chinkes DL, Irtun O, Wolfe RR. Anabolic action of insulin on skin wound protein is augmented by exogenous amino acids. Am J Physiol 2002; 282: E1308-15.
3. Liu Y, Zhang X, Zhang Z, Fang PY, Xu WS. [Effects of topical application of insulin on the wound healing in scalded rats]. Zhonghua Shao Shang Za Zhi 2004; 20: 98-101.
4. Liu Y, Zhang X, Zhang Z, Xu WS. [The influence of topical application of insulin on the formation of basement membrane in scalded rats]. Zhonghua Shao Shang Za Zhi 2005; 21: 445-7.
5. Zhang XJ, Chinkes DL, Sadagopa Ramanujam VM, Wolfe RR. Local injection of insulin-zinc stimulates DNA synthesis in skin donor site wound. Wound Repair Regen 2007; 15: 258-65.
6. Zhang XJ, Wu X, Wolf SE, Hawkins HK, Chinkes DL, Wolfe RR. Local insulin-zinc injection accelerates skin donor site wound healing. J Surg Res 2007; 142: 90-6.
7. Greenway SE, Filler LE, Greenway FL. Topical insulin in wound healing: a randomised, double blind, placebo controlled trial. J Wound Care 1999; 8: 526-8.