Altered distribution of β-catenin and prognostic roles in colorectal carcinogenesis

Scandinavian Journal of Gastroenterology

Volumn 43, Issue 4, 2008, Pages 456-464

  Chen, Senqing ^a,b   Liu, Juying ^b   Li, Guimei ^c   Mo, Fugen ^b   Xu, Xinyu ^b   Zhang, Tong ^b   Zhang, Xiaomei ^b   Li, Jintian ^b   Han, Xiao ^a   Sun, Yujie ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b JIANGSU CANCER HOSPITAL   (China)

^c The 81st Hospital of PLA   (China)

Author keywords

catenin; Colorectal carcinogenesis; Cyclooxygenase 2; E cadherin; Prognosis

Indexed keywords

BETA CATENIN; CYCLOOXYGENASE 2; UVOMORULIN;

ADOLESCENT; ADULT; AGED; ARTICLE; CANCER PATIENT; CANCER SURVIVAL; CARCINOGENESIS; CELL MEMBRANE; CELL NUCLEUS; COLON CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; CORRELATION COEFFICIENT; CYTOPLASM; DENATURING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE SEVERITY; EXON; FEMALE; GENE; GENE MUTATION; GENETIC SCREENING; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KAPLAN MEIER METHOD; LOG RANK TEST; MALE; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SURVIVAL RATE; TUMOR DIFFERENTIATION;

ADULT; AGED; AGED, 80 AND OVER; BETA CATENIN; CADHERINS; CELL MEMBRANE; CELL NUCLEUS; COLORECTAL NEOPLASMS; CYCLOOXYGENASE 2; CYTOPLASM; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MUTATION; PROGNOSIS; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL;

EID: 41349106822     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.1080/00365520701785194     Document Type: Article

References (39)

1. Kinzler KW, Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996;87:159-70.
2. Kolligs FT, Bommer G, Goke B. Wnt/beta-catenin/tcf signaling: a critical pathway in gastrointestinal tumorigenesis. Digestion 2002;66:131-44.
3. Giles RH, van Es JH, Clevers H. Caught up in a Wnt storm: Wnt signaling in cancer. Biochim Biophys Acta 2003;1653:1-24.
4. BenZeev A, Geiger B. Differential molecular interactions of beta-catenin and plakoglobin in adhesion, signaling and cancer. Curr Opin Cell Biol 1998;10:629-39.
5. Tetsu O, McCormick F. catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999;398:422-6.
6. Wong SC, Lo SF, Cheung MT. Quantification of beta-catenin mRNA in colorectal cancer and adenoma patients. Clin Cancer Res 2004;10:1613-7.
7. Wu WX, Zhang XH. Significance of β-catenin and Wnt pathway-related genes in colorectal adenoma. Chin J Cancer 2001;20:1005-7.
8. Brembeck FH, Rosario M, Birchmeier W. Balancing cell adhesion and Wnt signaling, the key role of beta-catenin. Curr Opin Genet Dev 2006;16:51-9.
9. van de Wetering, Barker N, Harkes IC, van der Heyden M, Dijk NJ, Hollestelle A, et al. Mutant E-cadherin breast cancer cells do not display constitutive Wnt signaling. Cancer Res 2001;61:278-84.
10. Nelson WJ, Nusse R. Convergence of Wnt, beta-catenin, and cadherin pathways. Science 2004;303:1483-7.
11. Vane JR, Botting RM. Mechanism of action of nonsteroidal anti-inflammatory drugs. Am J Med 1998;104:2-8S.
12. Coussens LM, Werb Z. Inflammation and cancer. Nature 2002;420:860-7.
13. Eberhart C, Coffey R, Radhika A, Giardiello F, Ferrenbach S, Dubois R. Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology 1004;107:1183-8.
14. 2. J Biol Chem 2002;277:2614-9.
15. McEntee MF, Chiu CH, Whelan J. Relationship of beta-catenin and Bcl-2 expression to sulindac-induced regression of intestinal tumors in Min mice. Carcinogenesis 1999;20:635-40.
16. Castellone MD, Teramoto H, Williams BO, Druey KM, Gutkind JS. Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-β-catenin signaling axis. Science 2005;310:1504-10.
17. Shao J, Jung C, Liu C, Sheng H. Prostaglandin E2 Stimulates the beta-catenin/T cell factor-dependent transcription in colon cancer. J Biol Chem 2005;280:26565-72.
18. Masunaga R, Kohno H, Dhar DK, Ohno S, Shibakita M, Kinugasa S, et al. Cyclooxygenase-2 expression correlates with tumor neovascularization and prognosis in human colorectal carcinoma patients. Clin Cancer Res 2000;6:4064-8.
19. Lei SL, Zhao H, Feng DZ. Expression and significance of E-cadherin and CD44v6 in colorectal carcinoma. J Clin Exp Med (China) 2006;5:104-5.
20. Maruyama K, Ochiai A, Akimoto S, Nakamura S, Baba S, Moriya Y, et al. Cytoplasmic beta-catenin accumulation as a predictor of the hematogenous metastasis in human colorectal cancer. Oncology 2000;59:302-9.
21. Kawakami M, Kimura Y, Furuhata T, Zenbutsu H, Yanai Y, Mukaiya M, et al. beta-Catenin alteration in cancer of the ampulla of Vater. J Exp Clin Cancer Res 2002;21:23-7.
22. Miller JR, Hocking AM, Brown JD, Moon RT. Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2+ pathways. Oncogene 1999;18:7860-72.
23. Valizadeh A, Karayiannakis AJ, El-Hariry I, Kmiot W, Pignatelli M. Expression of E-cadherin-associated molecules, α-,β- and γ-catenins and p120 in colorectal polyps. Am J Pathol 1997;150:1977-84.
24. Wong S, Lo E, Lee K, Chan JK, Hsiao WL. Prognostic and diagnostic significance of β-catenin nuclear immunostaining in colorectal cancer. Clin Cancer Res 2004;10:1401-8.
25. Iwamoto M, Hoffenberg EJ, Carethers JM, Doctolero R, Tajima A, Sugano K, et al. Nuclear accumulation of beta-catenin occurs commonly in the epithelial cells of juvenile polyps. Pediatr Res 2005;57:4-9.
26. Han SA, Chun H, Park CM, Kang SJ, Kim SH, Sohn D, et al. Prognostic significance of beta-catenin in colorectal cancer with liver metastasis. Clin Oncol (R Coll Radiol) 2006;18:761-7.
27. Wong SC, Lo ES, Chan AK, Lee KC, Hsiao WL. Nuclear beta catenin as a potential prognostic and diagnostic marker in patients with colorectal cancer from Hong Kong. Mol Pathol 2003;56:347-52.
28. Miyamoto S, Endoh Y, Hasebe T, Ishii G, Kodama K, Goya M, et al. Nuclear beta-catenin accumulation as a prognostic factor in Dukes' D human colorectal cancers. Oncol Rep 2004;12:245-51.
29. Fuchs SY, Ougolkov AV, Spiegelman VS, Minamoto T. Oncogenic β-catenin signaling networks in colorectal cancer. Cell Cycle 2005;4:1522-39.
30. Zhang M, Chen Z, Wang H. Immunohistochemical investigation of tumorigenic pathways in small intestinal adenocarcinoma: a comparison with colorectal adenocarcinoma. Mod Pathol 2006;19:573-80.
31. Suh EK, Gumbiner BM. Translocation of beta-catenin into the nucleus independent of interactions with FG-rich nucleoporins. Exp Cell Res 2003;290:447-56.
32. Henderson BR. Nuclear cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover. Nat Cell Biol 2001;2:653-60.
33. Wang D, Wang H, Shi Q, Katkuri S, Walhi W, Desvergne B, et al. Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta. Cancer Cell 2004;6:285-95.
34. Zhou J, Chen S, Zhang X, Zhou X, Zhu M, Feng B, et al. A novel APC gene germline mutation in a familial adenomatous polyposis pedigree. Chin J Med Genet 2006;23:388-91.
35. Chen SP, Tsai ST, Jao SW, Huang YL, Chao YC, Chen YL, et al. Single nucleotide polymorphisms of the APC gene and colorectal cancer risk: a case-control study in Taiwan. BMC Cancer 2006;6:83.
36. Yao H, Guo XL, Zhang SR, Shi QL. Expressions of axin and β-catenin in human colorectal cancer. Chin Remedies Clin 2006;6:805-8.
37. Van Aken E, De Wever O, Correia da Rocha AS, Mareel M. Defective E-cadherin/catenin complexes in human cancer. Virchows Arch 2001;439:725-51.
38. Roca F, Mauro LV, Morandi A, Bonadeo F, Vaccaro C, Quintana GO, et al. Prognostic value of E-cadherin, betacatenin, MMPs (7 and 9), and TIMPs (1 and 2) in patients with colorectal carcinoma. J Surg Oncol 2006;93:151-60.
39. Delektorskaya VV, Perevoshchikov AG, Golovkov DA, Kushlinskii NE. Expression of E-cadherin, beta-catenin, and CD-44v6 cell adhesion molecules in primary tumors and metastases of colorectal adenocarcinoma. Bull Exp Biol Med 2005;139:706-10.